Arnim Pause, M.Sc., Ph.D.
Arnim Pause, M.Sc., Ph.D.
Professor, Department of Biochemistry, Goodman Cencer Research Centre, McGill University
Verified email at
Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function.
A Pause, G Belsham, AC Gingras, O Donze, TA Lin, JC Lawrence, ...
Nature 371 (6500), 762-767, 1994
The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4γ and the translational repressors 4E-binding proteins
S Mader, H Lee, A Pause, N Sonenberg
Molecular and cellular biology, 1995
PHAS-I as a link between mitogen-activated protein kinase and translation initiation
TA Lin, X Kong, TAJ Haystead, A Pause, G Belsham, N Sonenberg, ...
Science 266 (5185), 653-656, 1994
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation
M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ...
Cell metabolism 18 (5), 698-711, 2013
Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF‐4A.
A Pause, N Sonenberg
The EMBO journal 11 (7), 2643-2654, 1992
Repression of cap‐dependent translation by 4E‐binding protein 1: competition with p220 for binding to eukaryotic initiation factor‐4E.
A Haghighat, S Mader, A Pause, N Sonenberg
The EMBO journal 14 (22), 5701-5709, 1995
Inhibition of transcription elongation by the VHL tumor suppressor protein
DR Duan, A Pause, WH Burgess, T Aso, DYT Chen, KP Garrett, ...
Science 269 (5229), 1402-1406, 1995
The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins
A Pause, S Lee, RA Worrell, DYT Chen, WH Burgess, WM Linehan, ...
Proceedings of the National Academy of Sciences 94 (6), 2156-2161, 1997
Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex
K Iwai, K Yamanaka, T Kamura, N Minato, RC Conaway, JW Conaway, ...
Proceedings of the National Academy of Sciences 96 (22), 12436-12441, 1999
The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5'secondary structure.
YV Svitkin, A Pause, A Haghighat, S Pyronnet, G Witherell, GJ Belsham, ...
Rna 7 (3), 382-394, 2001
Dominant negative mutants of mammalian translation initiation factor eIF‐4A define a critical role for eIF‐4F in cap‐dependent and cap‐independent initiation of translation.
A Pause, N Methot, Y Svitkin, WC Merrick, N Sonenberg
The EMBO journal 13 (5), 1205-1215, 1994
AMPK maintains cellular metabolic homeostasis through regulation of mitochondrial reactive oxygen species
RC Rabinovitch, B Samborska, B Faubert, EH Ma, SP Gravel, ...
Cell reports 21 (1), 1-9, 2017
The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis
A Pause, N Méthot, N Sonenberg
Molecular and cellular biology 13 (11), 6789-6798, 1993
An oxygen-regulated switch in the protein synthesis machinery
J Uniacke, CE Holterman, G Lachance, A Franovic, MD Jacob, MR Fabian, ...
Nature 486 (7401), 126-129, 2012
Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.
AC Gingras, Y Svitkin, GJ Belsham, A Pause, N Sonenberg
Proceedings of the National Academy of Sciences 93 (11), 5578-5583, 1996
Hepatitis C therapeutics: current status and emerging strategies
SL Tan, A Pause, Y Shi, N Sonenberg
Nature Reviews Drug Discovery 1 (11), 867-881, 2002
The von Hippel–Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal
A Pause, S Lee, KM Lonergan, RD Klausner
Proceedings of the National Academy of Sciences 95 (3), 993-998, 1998
The eIF4E-binding proteins 1 and 2 are negative regulators of cell growth
D Rousseau, AC Gingras, A Pause, N Sonenberg
Oncogene 13 (11), 2415-2420, 1996
mTOR pathways in cancer and autophagy
M Paquette, L El-Houjeiri, A Pause
Cancers 10 (1), 18, 2018
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