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Keith Mattern
Keith Mattern
Associate Principal Scientist, Merck & Co. Inc
Verified email at merck.com - Homepage
Title
Cited by
Cited by
Year
Kilo-Scale Electrochemical Oxidation of a Thioether to a Sulfone: A Workflow for Scaling up Electrosynthesis
C Bottecchia, D Lehnherr, F Lévesque, M Reibarkh, Y Ji, VL Rodrigues, ...
Organic Process Research & Development 26 (8), 2423-2437, 2022
282022
Electrochemical Recycling of Adenosine Triphosphate in Biocatalytic Reaction Cascades
S Ruccolo, G Brito, M Christensen, T Itoh, K Mattern, K Stone, ...
Journal of the American Chemical Society 144 (49), 22582-22588, 2022
202022
Automated End-to-End Workflow for Volumetric Mass-Transfer Coefficient (kLa) Characterization in Small-Molecule Pharmaceutical Development
K Mattern, ST Grosser
Organic Process Research & Development, 2023
52023
Discovery and development of an unusual organocatalyst for the Conversion of thymidine to furanoid glycal
PE Maligres, CK Chung, ZEX Dance, KA Mattern, EM Phillips, M Poirier, ...
Organic Process Research & Development 26 (3), 730-744, 2021
42021
Portable capillary LC for in‐line UV monitoring and MS detection: Comparable sensitivity and much lower solvent consumption
MB Hicks, K Mattern, J Fine, S Grosser, D Patel, L Weisel, P Aggarwal
Journal of Separation Science, 2300300, 2023
12023
Considerations for Biocatalytic Oxidation Development of a Key Intermediate for a Drug Candidate
M Zheng, S Badir, A Vikram, M Whittington, Y Qin, YJ Chen, KA Mattern, ...
2023 AIChE Annual Meeting, 2023
2023
Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir
MH Shaw, A Fryszkowska, O Alvizo, I Attadgie, M Borra-Garske, ...
2023
Development and Demonstration of a Co-feed Process to Address Form and Physical Attribute Control of the Gefapixant (MK-7264) Citrate Active Pharmaceutical Ingredient
Organic Process Research and Development 25 (3), 541-551, 2021
2021
Islatravir Penultimate Step Crystallization: Purification of an API in the Presence of High Protein Loading from an Enzymatic Cascade
E Margelefsky, SA Robaire, ST Grosser, T Kwok, M Miller, J Heltzel, K Sirk, ...
2020 Virtual AIChE Annual Meeting, 2020
2020
Chemical Engineers in the Pharmaceutical Industry
M Diwan, KA Mattern, K Springer, J Lott
2020 Virtual AIChE Annual Meeting, 2020
2020
Automated Platform for Experimental Execution and Model Regression of Volumetric Mass Transfer Coefficient and Vessel Characterization
KA Mattern, ST Grosser
2019 AIChE Annual Meeting, 2019
2019
Data-Rich Development of a Novel Biocatalytic Aerobic Oxidation across Scales
ST Grosser, SA Robaire, JH Forstater, A Fryszkowska, KA Mattern, ...
2019 AIChE Annual Meeting, 2019
2019
Solid-Phase Extractive Polymerization As a New Method for Polyanhydride Synthesis to Limit Oxidation during Polymerization and Improve Purity for Controlled Drug Delivery
AE Craven, J Titman, IJ O'Keefe, KA Mattern, BM Vogel
2019 AIChE Annual Meeting, 2019
2019
On the Synthesis of Pyrrolidone Containing Polyanhydrides
WE Heidel, KA Mattern, AE Craven, IJ O'Keefe, SL Paradise, BM Vogel
2018 AIChE Annual Meeting, 2018
2018
Synthesis of Pyrrolidone Containing Polyanhydrides for Controlled Drug Delivery
KA Mattern
2016
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