Kilo-Scale Electrochemical Oxidation of a Thioether to a Sulfone: A Workflow for Scaling up Electrosynthesis C Bottecchia, D Lehnherr, F Lévesque, M Reibarkh, Y Ji, VL Rodrigues, ... Organic Process Research & Development 26 (8), 2423-2437, 2022 | 28 | 2022 |
Electrochemical Recycling of Adenosine Triphosphate in Biocatalytic Reaction Cascades S Ruccolo, G Brito, M Christensen, T Itoh, K Mattern, K Stone, ... Journal of the American Chemical Society 144 (49), 22582-22588, 2022 | 20 | 2022 |
Automated End-to-End Workflow for Volumetric Mass-Transfer Coefficient (kLa) Characterization in Small-Molecule Pharmaceutical Development K Mattern, ST Grosser Organic Process Research & Development, 2023 | 5 | 2023 |
Discovery and development of an unusual organocatalyst for the Conversion of thymidine to furanoid glycal PE Maligres, CK Chung, ZEX Dance, KA Mattern, EM Phillips, M Poirier, ... Organic Process Research & Development 26 (3), 730-744, 2021 | 4 | 2021 |
Portable capillary LC for in‐line UV monitoring and MS detection: Comparable sensitivity and much lower solvent consumption MB Hicks, K Mattern, J Fine, S Grosser, D Patel, L Weisel, P Aggarwal Journal of Separation Science, 2300300, 2023 | 1 | 2023 |
Considerations for Biocatalytic Oxidation Development of a Key Intermediate for a Drug Candidate M Zheng, S Badir, A Vikram, M Whittington, Y Qin, YJ Chen, KA Mattern, ... 2023 AIChE Annual Meeting, 2023 | | 2023 |
Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir MH Shaw, A Fryszkowska, O Alvizo, I Attadgie, M Borra-Garske, ... | | 2023 |
Development and Demonstration of a Co-feed Process to Address Form and Physical Attribute Control of the Gefapixant (MK-7264) Citrate Active Pharmaceutical Ingredient Organic Process Research and Development 25 (3), 541-551, 2021 | | 2021 |
Islatravir Penultimate Step Crystallization: Purification of an API in the Presence of High Protein Loading from an Enzymatic Cascade E Margelefsky, SA Robaire, ST Grosser, T Kwok, M Miller, J Heltzel, K Sirk, ... 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
Chemical Engineers in the Pharmaceutical Industry M Diwan, KA Mattern, K Springer, J Lott 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
Automated Platform for Experimental Execution and Model Regression of Volumetric Mass Transfer Coefficient and Vessel Characterization KA Mattern, ST Grosser 2019 AIChE Annual Meeting, 2019 | | 2019 |
Data-Rich Development of a Novel Biocatalytic Aerobic Oxidation across Scales ST Grosser, SA Robaire, JH Forstater, A Fryszkowska, KA Mattern, ... 2019 AIChE Annual Meeting, 2019 | | 2019 |
Solid-Phase Extractive Polymerization As a New Method for Polyanhydride Synthesis to Limit Oxidation during Polymerization and Improve Purity for Controlled Drug Delivery AE Craven, J Titman, IJ O'Keefe, KA Mattern, BM Vogel 2019 AIChE Annual Meeting, 2019 | | 2019 |
On the Synthesis of Pyrrolidone Containing Polyanhydrides WE Heidel, KA Mattern, AE Craven, IJ O'Keefe, SL Paradise, BM Vogel 2018 AIChE Annual Meeting, 2018 | | 2018 |
Synthesis of Pyrrolidone Containing Polyanhydrides for Controlled Drug Delivery KA Mattern | | 2016 |