Bridget K. Wagner
Title
Cited by
Cited by
Year
Target identification and mechanism of action in chemical biology and drug discovery
M Schenone, V Dančík, BK Wagner, PA Clemons
Nature chemical biology 9 (4), 232-240, 2013
7452013
A single-cell transcriptomic map of the human and mouse pancreas reveals inter-and intra-cell population structure
M Baron, A Veres, SL Wolock, AL Faust, R Gaujoux, A Vetere, JH Ryu, ...
Cell systems 3 (4), 346-360. e4, 2016
5902016
Correlating chemical sensitivity and basal gene expression reveals mechanism of action
MG Rees, B Seashore-Ludlow, JH Cheah, DJ Adams, EV Price, S Gill, ...
Nature chemical biology 12 (2), 109-116, 2016
3762016
Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles
PA Clemons, NE Bodycombe, HA Carrinski, JA Wilson, AF Shamji, ...
Proceedings of the National Academy of Sciences 107 (44), 18787-18792, 2010
2712010
Targeting the pancreatic β-cell to treat diabetes
A Vetere, A Choudhary, SM Burns, BK Wagner
Nature reviews Drug discovery 13 (4), 278-289, 2014
2492014
Large-scale chemical dissection of mitochondrial function
BK Wagner, T Kitami, TJ Gilbert, D Peck, A Ramanathan, SL Schreiber, ...
Nature biotechnology 26 (3), 343-351, 2008
2102008
Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs
DJ Adams, M Dai, G Pellegrino, BK Wagner, AM Stern, AF Shamji, ...
Proceedings of the National Academy of Sciences 109 (38), 15115-15120, 2012
1822012
A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma
Y Yuan, Q Wang, J Paulk, S Kubicek, MM Kemp, DJ Adams, AF Shamji, ...
ACS chemical biology 7 (7), 1152-1157, 2012
1332012
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis
Y Zou, MJ Palte, AA Deik, H Li, JK Eaton, W Wang, YY Tseng, R Deasy, ...
Nature communications 10 (1), 1-13, 2019
1322019
A one-bead, one-stock solution approach to chemical genetics: part 2
PA Clemons, AN Koehler, BK Wagner, TG Sprigings, DR Spring, RW King, ...
Chemistry & biology 8 (12), 1183-1195, 2001
1292001
Inhibition of DYRK1A stimulates human β-cell proliferation
E Dirice, D Walpita, A Vetere, BC Meier, S Kahraman, J Hu, V Dančík, ...
Diabetes 65 (6), 1660-1671, 2016
1052016
Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms
V Rusu, E Hoch, JM Mercader, DE Tenen, M Gymrek, CR Hartigan, ...
Cell 170 (1), 199-212. e20, 2017
1012017
Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation
Z Arany, BK Wagner, Y Ma, J Chinsomboon, D Laznik, BM Spiegelman
Proceedings of the National Academy of Sciences 105 (12), 4721-4726, 2008
922008
Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis
DHC Chou, EB Holson, FF Wagner, AJ Tang, RL Maglathlin, TA Lewis, ...
Chemistry & biology 19 (6), 669-673, 2012
802012
Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections
PA Clemons, JA Wilson, V Dančík, S Muller, HA Carrinski, BK Wagner, ...
Proceedings of the National Academy of Sciences 108 (17), 6817-6822, 2011
792011
Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections
PA Clemons, JA Wilson, V Dančík, S Muller, HA Carrinski, BK Wagner, ...
Proceedings of the National Academy of Sciences 108 (17), 6817-6822, 2011
792011
The power of sophisticated phenotypic screening and modern mechanism-of-action methods
BK Wagner, SL Schreiber
Cell chemical biology 23 (1), 3-9, 2016
742016
A high-throughput platform to identify small-molecule inhibitors of CRISPR-Cas9
B Maji, SA Gangopadhyay, M Lee, M Shi, P Wu, R Heler, B Mok, D Lim, ...
Cell 177 (4), 1067-1079. e19, 2019
732019
Small-molecule inducers of insulin expression in pancreatic α-cells
D Fomina-Yadlin, S Kubicek, D Walpita, V Dančik, J Hecksher-Sřrensen, ...
Proceedings of the National Academy of Sciences 107 (34), 15099-15104, 2010
702010
Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells
Y Yuan, AJ Tang, AB Castoreno, SY Kuo, Q Wang, P Kuballa, R Xavier, ...
Cell death & disease 4 (6), e690-e690, 2013
682013
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