עקוב אחר
Georg Wuitschik
Georg Wuitschik
Senior Scientist, Roche
כתובת אימייל מאומתת בדומיין roche.com
כותרת
צוטט על ידי
צוטט על ידי
שנה
Oxetanes as versatile elements in drug discovery and synthesis
JA Burkhard, G Wuitschik, M Rogers‐Evans, K Müller, EM Carreira
Angewandte Chemie International Edition 49 (48), 9052-9067, 2010
4102010
Oxetanes in drug discovery: structural and synthetic insights
G Wuitschik, EM Carreira, B Wagner, H Fischer, I Parrilla, F Schuler, ...
Journal of medicinal chemistry 53 (8), 3227-3246, 2010
3812010
Oxetanes as promising modules in drug discovery
G Wuitschik, M Rogers‐Evans, K Müller, H Fischer, B Wagner, F Schuler, ...
Angewandte Chemie International Edition 45 (46), 7736-7739, 2006
2572006
Spirocyclic oxetanes: synthesis and properties
G Wuitschik, M Rogers-Evans, A Buckl, M Bernasconi, M Marki, T Godel, ...
Angewandte Chemie 120 (24), 4588, 2008
2192008
Piperazic acid-containing natural products: isolation, biological relevance and total synthesis
AJ Oelke, DJ France, T Hofmann, G Wuitschik, SV Ley
Natural Product Reports 28 (8), 1445-1471, 2011
902011
Synthesis and stability of oxetane analogs of thalidomide and lenalidomide
JA Burkhard, G Wuitschik, JM Plancher, M Rogers-Evans, EM Carreira
Organic letters 15 (17), 4312-4315, 2013
862013
Oxetane als vielseitige Bausteine in der Wirkstoff‐Forschung und Synthese
JA Burkhard, G Wuitschik, M Rogers‐Evans, K Müller, EM Carreira
Angewandte Chemie 122 (48), 9236-9251, 2010
852010
A Ru-Catalyzed Tandem Alkyne−Enone Coupling/Michael Addition:  Synthesis of 4-Methylene-2,6-cis-tetrahydropyrans
BM Trost, H Yang, G Wuitschik
Organic Letters 7 (21), 4761-4764, 2005
702005
Total synthesis of chloptosin
AJ Oelke, DJ France, T Hofmann, G Wuitschik, SV Ley
Angewandte Chemie International Edition 49 (35), 6139-6142, 2010
572010
Total synthesis of chloptosin: A dimeric cyclohexapeptide
AJ Oelke, F Antonietti, L Bertone, PB Cranwell, DJ France, RJM Goss, ...
Chemistry–A European Journal 17 (15), 4183-4194, 2011
512011
What can reaction databases teach us about Buchwald–Hartwig cross-couplings?
M Fitzner, G Wuitschik, RJ Koller, JM Adam, T Schindler, JL Reymond
Chemical science 11 (48), 13085-13093, 2020
452020
A Robust, Recyclable Resin for Decagram Scale Resolution of (±)‐Mefloquine and Other Chiral N‐Heterocycles
I Kreituss, KY Chen, SH Eitel, JM Adam, G Wuitschik, A Fettes, JW Bode
Angewandte Chemie International Edition 55 (4), 1553-1556, 2016
242016
Using data analysis to evaluate and compare chemical syntheses
D Kaiser, J Yang, G Wuitschik
Organic Process Research & Development 22 (9), 1222-1235, 2018
232018
The search for tricyanomethane (cyanoform)
D Šišak, LB McCusker, A Buckl, G Wuitschik, YL Wu, WB Schweizer, ...
Chemistry–A European Journal 16 (24), 7224-7230, 2010
222010
Machine Learning C–N Couplings: Obstacles for a General-Purpose Reaction Yield Prediction
M Fitzner, G Wuitschik, R Koller, JM Adam, T Schindler
ACS omega 8 (3), 3017-3025, 2023
152023
Oxetanes in drug discovery
G Wuitschik
ETH Zurich, 2008
152008
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning
DF Nippa, K Atz, R Hohler, AT Müller, A Marx, C Bartelmus, G Wuitschik, ...
Nature Chemistry 16 (2), 239-248, 2024
142024
Tricyanomethane and its salts with nitrogen bases: A correction of sixteen reports
K Banert, M Hagedorn
Synlett 30 (12), 1427-1430, 2019
142019
Accounting for different reactivities of sulfinate and thiosulfate salts in regioselective azetidine coupling via C–H sulfenylation of indoles
MAE Al-Saedy, ACMA Nassoy, JPA Harrity
Synlett 29 (03), 349-353, 2018
72018
Oxetan‐3‐one: Chemistry and Synthesis
G Wuitschik, EM Carreira, M Rogers‐Evans, K Muller
ChemInform 40 (13), no-no, 2009
72009
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מאמרים 1–20