Comparison of breast cancer molecular features and survival by African and European ancestry in The Cancer Genome Atlas D Huo, H Hu, SK Rhie, ER Gamazon, AD Cherniack, J Liu, TF Yoshimatsu, ... JAMA oncology 3 (12), 1654-1662, 2017 | 258 | 2017 |
Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis SP Pitroda, NN Khodarev, L Huang, A Uppal, SC Wightman, S Ganai, ... Nature communications 9 (1), 1793, 2018 | 243 | 2018 |
The 8q24 gene desert: an oasis of non-coding transcriptional activity K Huppi, JJ Pitt, BM Wahlberg, NJ Caplen Frontiers in genetics 3, 69, 2012 | 175 | 2012 |
Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA M Mackiewicz, K Huppi, JJ Pitt, TH Dorsey, S Ambs, NJ Caplen Breast cancer research and treatment 130, 663-679, 2011 | 148 | 2011 |
Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer J Camps, JJ Pitt, G Emons, AB Hummon, CM Case, M Grade, TL Jones, ... Cancer research 73 (6), 2003-2013, 2013 | 118 | 2013 |
Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features JJ Pitt, M Riester, Y Zheng, TF Yoshimatsu, A Sanni, O Oluwasola, ... Nature communications 9 (1), 4181, 2018 | 105 | 2018 |
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors J Cheng, J Demeulemeester, DC Wedge, HKM Vollan, JJ Pitt, ... Nature Communications 8 (1), 1221, 2017 | 101 | 2017 |
Inducing apoptosis in chemotherapy‐resistant B‐lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti‐apoptotic unfolded protein … FM Uckun, S Qazi, Z Ozer, AL Garner, J Pitt, H Ma, KD Janda British journal of haematology 153 (6), 741-752, 2011 | 98 | 2011 |
Immune pathway upregulation and lower genomic instability distinguish EBV-positive nodal T/NK-cell lymphoma from ENKTL and PTCL-NOS CMM Wai, S Chen, T Phyu, S Fan, SM Leong, W Zheng, LCY Low, ... Haematologica 107 (8), 1864, 2022 | 54 | 2022 |
Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the … AB Hummon, JJ Pitt, J Camps, G Emons, SB Skube, K Huppi, TL Jones, ... Molecular cancer 11, 1-22, 2012 | 40 | 2012 |
Pan-cancer pervasive upregulation of 3′ UTR splicing drives tumourigenesis JJ Chan, B Zhang, XH Chew, A Salhi, ZH Kwok, CY Lim, N Desi, ... Nature Cell Biology 24 (6), 928-939, 2022 | 38 | 2022 |
Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer MM Hoppe, P Jaynes, JD Wardyn, SS Upadhyayula, TZ Tan, S Lie, ... EMBO molecular medicine 13 (5), e13366, 2021 | 37 | 2021 |
Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening SV Garimella, K Gehlhaus, JL Dine, JJ Pitt, M Grandin, S Chakka, ... Breast Cancer Research 16, 1-21, 2014 | 36 | 2014 |
Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes N Ansari-Pour, Y Zheng, TF Yoshimatsu, A Sanni, M Ajani, JB Reynier, ... Nature communications 12 (1), 6946, 2021 | 34 | 2021 |
Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity O Ou, K Huppi, S Chakka, K Gehlhaus, W Dubois, J Patel, J Chen, ... Cancer letters 354 (2), 336-347, 2014 | 28 | 2014 |
Profiling and predicting application performance on the cloud M Baughman, R Chard, L Ward, J Pitt, K Chard, I Foster 11th IEEE/ACM International Conference on Utility and Cloud Computing (UCC), 2018 | 26 | 2018 |
Germline variants and somatic mutation signatures of breast cancer across populations of African and European ancestry in the US and Nigeria S Wang, JJ Pitt, Y Zheng, TF Yoshimatsu, G Gao, A Sanni, O Oluwasola, ... International journal of cancer 145 (12), 3321-3333, 2019 | 23 | 2019 |
JAK3 pathway is constitutively active in B-lineage acute lymphoblastic leukemia FM Uckun, J Pitt, S Qazi Expert review of anticancer therapy 11 (1), 37-48, 2011 | 20 | 2011 |
Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation N Padmanabhan, HK Kyon, A Boot, K Lim, S Srivastava, S Chen, Z Wu, ... Genome biology 22, 1-29, 2021 | 19 | 2021 |
Genomic instability and mouse microRNAs K Huppi, J Pitt, B Wahlberg, NJ Caplen Toxicology mechanisms and methods 21 (4), 325-333, 2011 | 16 | 2011 |