Marc Hafner
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Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs
M Hafner, M Niepel, M Chung, PK Sorger
Nature methods 13 (6), 521-527, 2016
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations
AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ...
Cell systems 6 (1), 13-24, 2018
LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures
Q Duan, C Flynn, M Niepel, M Hafner, JL Muhlich, NF Fernandez, ...
Nucleic acids research 42 (W1), W449-W460, 2014
L1000CDS2: LINCS L1000 characteristic direction signatures search engine
Q Duan, SP Reid, NR Clark, Z Wang, NF Fernandez, AD Rouillard, ...
NPJ Systems Biology and Applications 2, 16015, 2016
Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity
M Hafner, CE Mills, K Subramanian, C Chen, M Chung, SA Boswell, ...
Cell Chemical Biology, 2019
Fractional killing arises from cell‐to‐cell variability in overcoming a caspase activity threshold
J Roux, M Hafner, S Bandara, JJ Sims, H Hudson, D Chai, PK Sorger
Molecular systems biology 11 (5), 803, 2015
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility
J Guan, W Zhou, M Hafner, RA Blake, C Chalouni, IP Chen, T De Bruyn, ...
Cell 178 (4), 949-963. e18, 2019
A quantitative approach to screen for nephrotoxic compounds in vitro
M Adler, S Ramm, M Hafner, JL Muhlich, EM Gottwald, E Weber, A Jaklic, ...
Journal of the American Society of Nephrology 27 (4), 1015-1028, 2016
A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines
M Niepel, M Hafner, CE Mills, K Subramanian, EH Williams, M Chung, ...
Cell Systems, 2019
Few-shot learning creates predictive models of drug response that translate from high-throughput screens to individual patients
J Ma, SH Fong, Y Luo, CJ Bakkenist, JP Shen, S Mourragui, LFA Wessels, ...
Nature Cancer 2 (2), 233-244, 2021
Efficient characterization of high-dimensional parameter spaces for systems biology
E Zamora-Sillero, M Hafner, A Ibig, J Stelling, A Wagner
BMC systems biology 5 (1), 1-22, 2011
Profiles of Basal and Stimulated Receptor Signaling Networks Predict Drug Response in Breast Cancer Lines
M Niepel, M Hafner, EA Pace, M Chung, DH Chai, L Zhou, B Schoeberl, ...
Science Signaling 6 (294), ra84, 2013
‘Glocal’ robustness analysis and model discrimination for circadian oscillators
M Hafner, H Koeppl, M Hasler, A Wagner
PLoS computational biology 5 (10), e1000534, 2009
Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling
M Niepel, M Hafner, Q Duan, Z Wang, EO Paull, M Chung, X Lu, JM Stuart, ...
Nature Communications 8 (1), 1186, 2017
Effect of network architecture on synchronization and entrainment properties of the circadian oscillations in the suprachiasmatic nucleus
M Hafner, H Koeppl, D Gonze
PLoS computational biology 8 (3), e1002419, 2012
GRcalculator: an online tool for calculating and mining dose–response data
NA Clark, M Hafner, M Kouril, EH Williams, JL Muhlich, M Pilarczyk, ...
BMC Cancer 17 (1), 698, 2017
Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics
M Hafner, M Niepel, PK Sorger
Nature Biotechnology 35 (6), 500-502, 2017
Cheminformatics tools for analyzing and designing optimized Small-Molecule collections and libraries
N Moret, NA Clark, M Hafner, Y Wang, E Lounkine, M Medvedovic, ...
Cell chemical biology 26 (5), 765-777. e3, 2019
Analysis of growth factor signaling in genetically diverse breast cancer lines
M Niepel, M Hafner, EA Pace, M Chung, DH Chai, L Zhou, JL Muhlich, ...
BMC biology 12 (1), 1-13, 2014
Modular design of artificial tissue homeostasis: robust control through synthetic cellular heterogeneity
M Miller, M Hafner, E Sontag, N Davidsohn, S Subramanian, PEM Purnick, ...
PLoS computational biology 8 (7), e1002579, 2012
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