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Madeline R. Luth, Ph.D.
Madeline R. Luth, Ph.D.
Unknown affiliation
Verified email at ucsd.edu
Title
Cited by
Cited by
Year
Biochar characteristics relate to its utility as an alternative soil inoculum carrier to peat and vermiculite
L Hale, M Luth, D Crowley
Soil Biology and Biochemistry 81, 228-235, 2015
1702015
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials
Y Antonova-Koch, S Meister, M Abraham, MR Luth, S Ottilie, AK Lukens, ...
Science 362 (6419), eaat9446, 2018
1102018
Evaluation of pinewood biochar as a carrier of bacterial strain Enterobacter cloacae UW5 for soil inoculation
L Hale, M Luth, R Kenney, D Crowley
Applied Soil Ecology 84, 192-199, 2014
1032014
Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery
MR Luth, P Gupta, S Ottilie, EA Winzeler
ACS infectious diseases 4 (3), 301-314, 2018
702018
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial …
BH Stokes, E Yoo, JM Murithi, MR Luth, P Afanasyev, PCA da Fonseca, ...
PLoS pathogens 15 (6), e1007722, 2019
612019
Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome
SC Xie, DL Gillett, NJ Spillman, C Tsu, MR Luth, S Ottilie, S Duffy, ...
Journal of medicinal chemistry 61 (22), 10053-10066, 2018
612018
CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM)
A Debnath, CM Calvet, G Jennings, W Zhou, A Aksenov, MR Luth, ...
PLoS neglected tropical diseases 11 (12), e0006104, 2017
522017
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention
RL Summers, CFA Pasaje, JP Pisco, J Striepen, MR Luth, K Kumpornsin, ...
Cell chemical biology 29 (2), 191-201. e8, 2022
392022
Evolution of resistance in vitro reveals mechanisms of artemisinin activity in Toxoplasma gondii
A Rosenberg, MR Luth, EA Winzeler, M Behnke, LD Sibley
Proceedings of the National Academy of Sciences 116 (52), 26881-26891, 2019
392019
In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model
REK Mandt, MJ Lafuente-Monasterio, T Sakata-Kato, MR Luth, D Segura, ...
Science translational medicine 11 (521), eaav1636, 2019
332019
Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway
GM LaMonte, F Rocamora, DS Marapana, NF Gnädig, S Ottilie, MR Luth, ...
Nature communications 11 (1), 1780, 2020
302020
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy
SC Xie, RD Metcalfe, E Dunn, CJ Morton, SC Huang, T Puhalovich, Y Du, ...
Science 376 (6597), 1074-1079, 2022
262022
Probing the open global health chemical diversity library for multistage-active starting points for next-generation antimalarials
M Abraham, K Gagaring, ML Martino, M Vanaerschot, DM Plouffe, J Calla, ...
ACS Infectious Diseases 6 (4), 613-628, 2020
262020
Efficacy of post-harvest rinsing and bleach disinfection of E. coli O157: H7 on spinach leaf surfaces
NM Kinsinger, HM Mayton, MR Luth, SL Walker
Food microbiology 62, 212-220, 2017
202017
PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum
F Rocamora, P Gupta, ES Istvan, MR Luth, EF Carpenter, K Kümpornsin, ...
ACS Infectious Diseases 7 (4), 811-825, 2021
132021
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages
LB Arendse, JM Murithi, T Qahash, CFA Pasaje, LC Godoy, S Dey, ...
Science translational medicine 14 (667), eabo7219, 2022
112022
Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance
MA Tye, NC Payne, C Johansson, K Singh, SA Santos, L Fagbami, A Pant, ...
Nature Communications 13 (1), 4976, 2022
102022
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target
ES Istvan, F Guerra, M Abraham, KS Huang, F Rocamora, H Zhao, L Xu, ...
Science translational medicine 15 (686), eadc9249, 2023
72023
Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance
S Ottilie, MR Luth, E Hellemann, GM Goldgof, E Vigil, P Kumar, ...
Communications Biology 5 (1), 128, 2022
72022
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials. Science 362: eaat9446
Y Antonova-Koch, S Meister, M Abraham, MR Luth, S Ottilie, AK Lukens, ...
72018
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