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Alex Drohat
Alex Drohat
Professor of Biochemistry and Molecular Biology, University of Maryland School of Medicine
Verified email at som.umaryland.edu - Homepage
Title
Cited by
Cited by
Year
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine potential implications for active demethylation of CpG sites
A Maiti, AC Drohat
Journal of Biological Chemistry 286 (41), 35334-35338, 2011
9992011
Replication-dependent unhooking of DNA interstrand cross-links by the NEIL3 glycosylase
DR Semlow, J Zhang, M Budzowska, AC Drohat, JC Walter
Cell 167 (2), 498-511. e14, 2016
2162016
Solution structure of calcium-bound rat S100B (ββ) as determined by nuclear magnetic resonance spectroscopy
AC Drohat, DM Baldisseri, RR Rustandi, DJ Weber
Biochemistry 37 (9), 2729-2740, 1998
2031998
Specificity of human thymine DNA glycosylase depends on N-glycosidic bond stability
MT Bennett, MT Rodgers, AS Hebert, LE Ruslander, L Eisele, AC Drohat
Journal of the American Chemical Society 128 (38), 12510-12519, 2006
1892006
The Ca2+-dependent interaction of S100B (ββ) with a peptide derived from p53
RR Rustandi, AC Drohat, DM Baldisseri, PT Wilder, DJ Weber
Biochemistry 37 (7), 1951-1960, 1998
1701998
Solution structure of rat apo-S100B (ββ) as determined by NMR spectroscopy
AC Drohat, JC Amburgey, F Abildgaard, MR Starich, D Baldisseri, ...
Biochemistry 35 (36), 11577-11588, 1996
1591996
Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited
G Xiao, M Tordova, J Jagadeesh, AC Drohat, JT Stivers, GL Gilliland
Proteins: Structure, Function, and Bioinformatics 35 (1), 13-24, 1999
1381999
Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition
A Maiti, MT Morgan, E Pozharski, AC Drohat
Proceedings of the National Academy of Sciences 105 (26), 8890-8895, 2008
1342008
Role of electrophilic and general base catalysis in the mechanism of Escherichia coli uracil DNA glycosylase
AC Drohat, J Jagadeesh, E Ferguson, JT Stivers
Biochemistry 38 (37), 11866-11875, 1999
1311999
The use of dipolar couplings for determining the solution structure of rat apo‐S100B (ββ)
AC Drohat, N Tjandra, DM Baldisseri, DJ Weber
Protein Science 8 (4), 800-809, 1999
1221999
S100B (ββ) inhibits the protein kinase C‐dependent phosphorylation of a peptide derived from p53 in a Ca2+‐dependent manner
PT Wilder, RR Rustandi, AC Drohat, DJ Weber
Protein science 7 (3), 794-798, 1998
1181998
Excision of 5-Halogenated Uracils by Human Thymine DNA Glycosylase ROBUST ACTIVITY FOR DNA CONTEXTS OTHER THAN CpG
MT Morgan, MT Bennett, AC Drohat
Journal of Biological Chemistry 282 (38), 27578-27586, 2007
1162007
Coordinating the initial steps of base excision repair apurinic/apyrimidinic endonuclease 1 actively stimulates thymine DNA glycosylase by disrupting the product complex
ME Fitzgerald, AC Drohat
Journal of Biological Chemistry 283 (47), 32680-32690, 2008
1092008
Role of base excision repair in maintaining the genetic and epigenetic integrity of CpG sites
A Bellacosa, AC Drohat
DNA repair 32, 33-42, 2015
1072015
NMR Evidence for an Unusually Low N1 p K a for Uracil Bound to Uracil DNA Glycosylase: Implications for Catalysis
AC Drohat, JT Stivers
Journal of the American Chemical Society 122 (8), 1840-1841, 2000
1002000
Role of Base Excision “Repair” Enzymes in Erasing Epigenetic Marks from DNA
AC Drohat, CT Coey
Chemical reviews 116 (20), 12711-12729, 2016
992016
Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral …
AC Drohat, G Xiao, M Tordova, J Jagadeesh, KW Pankiewicz, ...
Biochemistry 38 (37), 11876-11886, 1999
951999
Divergent mechanisms for enzymatic excision of 5-formylcytosine and 5-carboxylcytosine from DNA
A Maiti, AZ Michelson, CJ Armwood, JK Lee, AC Drohat
Journal of the American Chemical Society 135 (42), 15813-15822, 2013
872013
Escherichia coli uracil DNA glycosylase: NMR characterization of the short hydrogen bond from His187 to uracil O2
AC Drohat, JT Stivers
Biochemistry 39 (39), 11865-11875, 2000
872000
The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase
X Guan, A Madabushi, DY Chang, ME Fitzgerald, G Shi, AC Drohat, AL Lu
Nucleic acids research 35 (18), 6207-6218, 2007
832007
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