| Crystal structure of a bacterial chitinase at 2.3 Å resolution A Perrakis, I Tews, Z Dauter, AB Oppenheim, I Chet, KS Wilson, ... Structure 2 (12), 1169-1180, 1994 | 525 | 1994 |
| Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay–Sachs disease I Tews, A Perrakis, A Oppenheim, Z Dauter, KS Wilson, CE Vorgias Nature structural biology 3 (7), 638-648, 1996 | 453 | 1996 |
| Substrate-assisted catalysis unifies two families of chitinolytic enzymes I Tews, AC Terwisscha van Scheltinga, A Perrakis, KS Wilson, BW Dijkstra Journal of the American Chemical Society 119 (34), 7954-7959, 1997 | 371 | 1997 |
| Two independent routes of de novo vitamin B6 biosynthesis: not that different after all TB Fitzpatrick, N Amrhein, B Kappes, P Macheroux, I Tews, T Raschle Biochemical Journal 407 (1), 1-13, 2007 | 231 | 2007 |
| The molecular chaperone Hsp90 delivers precursor proteins to the chloroplast import receptor Toc64 S Qbadou, T Becker, O Mirus, I Tews, J Soll, E Schleiff The EMBO journal 25 (9), 1836-1847, 2006 | 206 | 2006 |
| Specificity Determinants of Recruitment Peptides Bound to Phospho-CDK2/Cyclin A, ED Lowe, I Tews, KY Cheng, NR Brown, S Gul, MEM Noble, SJ Gamblin, ... Biochemistry 41 (52), 15625-15634, 2002 | 206 | 2002 |
| Cell surface counter receptors are essential components of the unconventional export machinery of galectin-1 C Seelenmeyer, S Wegehingel, I Tews, M Künzler, M Aebi, W Nickel The Journal of cell biology 171 (2), 373-381, 2005 | 148 | 2005 |
| The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme I Tews, F Findeisen, I Sinning, A Schultz, JE Schultz, JU Linder Science 308 (5724), 1020-1023, 2005 | 142 | 2005 |
| Structure of a bacterial pyridoxal 5′-phosphate synthase complex M Strohmeier, T Raschle, J Mazurkiewicz, K Rippe, I Sinning, ... Proceedings of the National Academy of Sciences 103 (51), 19284-19289, 2006 | 139 | 2006 |
| A direct role for phosphatidylinositol‐4, 5‐bisphosphate in unconventional secretion of fibroblast growth factor 2 K Temmerman, AD Ebert, HM Müller, I Sinning, I Tews, W Nickel Traffic 9 (7), 1204-1217, 2008 | 137 | 2008 |
| OX40: Structure and function–What questions remain? J Willoughby, J Griffiths, I Tews, MS Cragg Molecular immunology 83, 13-22, 2017 | 132 | 2017 |
| The CCP4 suite: integrative software for macromolecular crystallography J Agirre, M Atanasova, H Bagdonas, CB Ballard, A Baslé, ... Acta Crystallographica Section D: Structural Biology 79 (6), 449-461, 2023 | 126 | 2023 |
| Pyridoxal phosphate: biosynthesis and catabolism T Mukherjee, J Hanes, I Tews, SE Ealick, TP Begley Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1814 (11), 1585-1596, 2011 | 110 | 2011 |
| Complex interplay between epitope specificity and isotype dictates the biological activity of anti-human CD40 antibodies X Yu, HTC Chan, CM Orr, O Dadas, SG Booth, LN Dahal, CA Penfold, ... Cancer cell 33 (4), 664-675. e4, 2018 | 97 | 2018 |
| Solubilization of aggregated proteins by ClpB/DnaK relies on the continuous extraction of unfolded polypeptides C Schlieker, I Tews, B Bukau, A Mogk FEBS letters 578 (3), 351-356, 2004 | 96 | 2004 |
| The N‐terminal cysteine pair of yeast sulfhydryl oxidase Erv1p is essential for in vivo activity and interacts with the primary redox centre G Hofhaus, JE Lee, I Tews, B Rosenberg, T Lisowsky European journal of biochemistry 270 (7), 1528-1535, 2003 | 95 | 2003 |
| Vitamin B6 biosynthesis by the malaria parasite Plasmodium falciparum: biochemical and structural insights M Gengenbacher, TB Fitzpatrick, T Raschle, K Flicker, I Sinning, S Muller, ... Journal of Biological Chemistry 281 (6), 3633-3641, 2006 | 94 | 2006 |
| N-Acetylglucosaminidase (chitobiase) from Serratia marcescens: gene sequence, and protein production and purification in Escherichia coli I Tews, R Vincentelli, CE Vorgias Gene 170 (1), 63-67, 1996 | 89 | 1996 |
| Functional analysis of PDX2 from Arabidopsis, a glutaminase involved in vitamin B6 biosynthesis M Tambasco-Studart, I Tews, N Amrhein, TB Fitzpatrick Plant physiology 144 (2), 915-925, 2007 | 84 | 2007 |
| Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator CW Phippen, H Mikolajek, HG Schlaefli, CW Keevil, JS Webb, I Tews FEBS letters 588 (24), 4631-4636, 2014 | 72 | 2014 |
Anastassis PerrakisDivision of Biochemistry, Netherlands Cancer Institute and Oncode Institute, Prof Utrecht UVerified email at nki.nl
