Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences I Coin, M Beyermann, M Bienert Nature protocols 2 (12), 3247-3256, 2007 | 795 | 2007 |
Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR I Coin, V Katritch, T Sun, Z Xiang, FY Siu, M Beyermann, RC Stevens, ... Cell 155 (6), 1258-1269, 2013 | 184 | 2013 |
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity Z Xiang, H Ren, YS Hu, I Coin, J Wei, H Cang, L Wang Nature methods 10 (9), 885-888, 2013 | 158 | 2013 |
Depsipeptide methodology for solid-phase peptide synthesis: circumventing side reactions and development of an automated technique via depsidipeptide units I Coin, R Dölling, E Krause, M Bienert, M Beyermann, CD Sferdean, ... The Journal of organic chemistry 71 (16), 6171-6177, 2006 | 142 | 2006 |
In vivo expression of a light-activatable potassium channel using unnatural amino acids JY Kang, D Kawaguchi, I Coin, Z Xiang, DDM O’Leary, PA Slesinger, ... Neuron 80 (2), 358-370, 2013 | 136 | 2013 |
Expanding the Genetic Code of Caenorhabditis elegans Using Bacterial Aminoacyl-tRNA Synthetase/tRNA Pairs AR Parrish, X She, Z Xiang, I Coin, Z Shen, SP Briggs, A Dillin, L Wang ACS chemical biology 7 (7), 1292-1302, 2012 | 128 | 2012 |
Designer tRNAs for efficient incorporation of non-canonical amino acids by the pyrrolysine system in mammalian cells R Serfling, C Lorenz, M Etzel, G Schicht, T Böttke, M Mörl, I Coin Nucleic acids research 46 (1), 1-10, 2018 | 122 | 2018 |
Photo‐cross‐linkers incorporated into G‐protein‐coupled receptors in mammalian cells: a ligand comparison I Coin, MH Perrin, WW Vale, L Wang Angewandte Chemie International Edition 50 (35), 8077-8081, 2011 | 73 | 2011 |
Application of non-canonical crosslinking amino acids to study protein–protein interactions in live cells I Coin Current opinion in chemical biology 46, 156-163, 2018 | 69 | 2018 |
The depsipeptide method for solid‐phase synthesis of difficult peptides I Coin Journal of Peptide Science 16 (5), 223-230, 2010 | 62 | 2010 |
Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells L Seidel, B Zarzycka, SA Zaidi, V Katritch, I Coin eLife 6, 2017 | 54 | 2017 |
Total synthesis in solution of alamethicin F50/5 by an easily tunable segment condensation approach C Peggion, I Coin, C Toniolo Peptide Science 76 (6), 485-493, 2004 | 49 | 2004 |
Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation LJ Clark, J Krieger, AD White, V Bondarenko, S Lei, F Fang, JY Lee, ... Nature chemical biology 16 (10), 1096-1104, 2020 | 47 | 2020 |
Quantitative single-residue bioorthogonal labeling of G protein-coupled receptors in live cells R Serfling, L Seidel, A Bock, MJ Lohse, P Annibale, I Coin ACS chemical biology 14 (6), 1141-1149, 2019 | 42 | 2019 |
Alamethicin interaction with lipid membranes: a spectroscopic study on synthetic analogues L Stella, M Burattini, C Mazzuca, A Palleschi, M Venanzi, I Coin, ... Chemistry & Biodiversity 4 (6), 1299-1312, 2007 | 42 | 2007 |
Exploring GPCR‐arrestin interfaces with genetically encoded crosslinkers T Böttke, S Ernicke, R Serfling, C Ihling, E Burda, VV Gurevich, A Sinz, ... EMBO reports 21 (11), e50437, 2020 | 41 | 2020 |
Solid-phase synthesis of a cyclodepsipeptide: cotransin. I Coin, M Beerbaum, P Schmieder, M Bienert, M Beyermann Organic letters 10 (17), 3857, 2008 | 37 | 2008 |
Capturing peptide–GPCR interactions and their dynamics A Kaiser, I Coin Molecules 25 (20), 4724, 2020 | 32 | 2020 |
Structural details of a Class B GPCR-arrestin complex revealed by genetically encoded crosslinkers in living cells Y Aydin, T Böttke, JH Lam, S Ernicke, A Fortmann, M Tretbar, B Zarzycka, ... Nature Communications 14 (1), 1151, 2023 | 30 | 2023 |
Incorporation of unnatural amino acids into proteins expressed in mammalian cells R Serfling, I Coin Methods in enzymology 580, 89-107, 2016 | 28 | 2016 |