Osteoblastic cells regulate the haematopoietic stem cell niche LM Calvi, GB Adams, KW Weibrecht, JM Weber, DP Olson, MC Knight, ... Nature 425 (6960), 841-846, 2003 | 4437 | 2003 |
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche S Méndez-Ferrer, TV Michurina, F Ferraro, AR Mazloom, BD MacArthur, ... nature 466 (7308), 829-834, 2010 | 3936 | 2010 |
The bone marrow niche for haematopoietic stem cells SJ Morrison, DT Scadden Nature 505 (7483), 327-334, 2014 | 2600 | 2014 |
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer CG Willett, Y Boucher, E Di Tomaso, DG Duda, LL Munn, RT Tong, ... Nature medicine 10 (2), 145-147, 2004 | 2506 | 2004 |
The stem-cell niche as an entity of action DT Scadden nature 441 (7097), 1075-1079, 2006 | 2444 | 2006 |
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells M Lewin, N Carlesso, CH Tung, XW Tang, D Cory, DT Scadden, ... Nature biotechnology 18 (4), 410-414, 2000 | 2359 | 2000 |
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients TT Batchelor, AG Sorensen, E di Tomaso, WT Zhang, DG Duda, ... Cancer cell 11 (1), 83-95, 2007 | 2108 | 2007 |
Hematopoietic stem cell quiescence maintained by p21cip1/waf1 T Cheng, N Rodrigues, H Shen, Y Yang, D Dombkowski, M Sykes, ... Science 287 (5459), 1804-1808, 2000 | 1648 | 2000 |
Biology of hematopoietic stem cells and progenitors: implications for clinical application M Kondo, AJ Wagers, MG Manz, SS Prohaska, DC Scherer, GF Beilhack, ... Annual review of immunology 21 (1), 759-806, 2003 | 1419 | 2003 |
Bayesian approach to single-cell differential expression analysis PV Kharchenko, L Silberstein, DT Scadden Nature methods 11 (7), 740-742, 2014 | 1415 | 2014 |
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a V Janzen, R Forkert, HE Fleming, Y Saito, MT Waring, DM Dombkowski, ... Nature 443 (7110), 421-426, 2006 | 1305 | 2006 |
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia MHGP Raaijmakers, S Mukherjee, S Guo, S Zhang, T Kobayashi, ... Nature 464 (7290), 852-857, 2010 | 1296 | 2010 |
Direct measurement of local oxygen concentration in the bone marrow of live animals JA Spencer, F Ferraro, E Roussakis, A Klein, J Wu, JM Runnels, W Zaher, ... Nature 508 (7495), 269-273, 2014 | 1230 | 2014 |
In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment DA Sipkins, X Wei, JW Wu, JM Runnels, D Côté, TK Means, AD Luster, ... Nature 435 (7044), 969-973, 2005 | 1079 | 2005 |
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation KW Orford, DT Scadden Nature Reviews Genetics 9 (2), 115-128, 2008 | 1074 | 2008 |
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche C Lo Celso, HE Fleming, JW Wu, CX Zhao, S Miake-Lye, J Fujisaki, ... Nature 457 (7225), 92-96, 2009 | 1068 | 2009 |
Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis M Demers, DS Krause, D Schatzberg, K Martinod, JR Voorhees, TA Fuchs, ... Proceedings of the National Academy of Sciences 109 (32), 13076-13081, 2012 | 978 | 2012 |
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor GB Adams, KT Chabner, IR Alley, DP Olson, ZM Szczepiorkowski, ... Nature 439 (7076), 599-603, 2006 | 941 | 2006 |
A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection LM Albritton, L Tseng, D Scadden, JM Cunningham Cell 57 (4), 659-666, 1989 | 936 | 1989 |
Oocyte generation in adult mammalian ovaries by putative germ cells in bone marrow and peripheral blood J Johnson, J Bagley, M Skaznik-Wikiel, HJ Lee, GB Adams, Y Niikura, ... Cell 122 (2), 303-315, 2005 | 913 | 2005 |