| The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells M Van De Wetering, E Sancho, C Verweij, W De Lau, I Oving, A Hurlstone, ... Cell 111 (2), 241-250, 2002 | 2258 | 2002 |
| AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27 kip1 RH Medema, GJPL Kops, JL Bos, BMT Burgering Nature 404 (6779), 782-787, 2000 | 1661 | 2000 |
| Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress GJPL Kops, TB Dansen, PE Polderman, I Saarloos, KWA Wirtz, PJ Coffer, ... Nature 419 (6904), 316-321, 2002 | 1554 | 2002 |
| Cell death by mitotic catastrophe: a molecular definition M Castedo, JL Perfettini, T Roumier, K Andreau, R Medema, G Kroemer Oncogene 23 (16), 2825-2837, 2004 | 1419 | 2004 |
| Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1 PF Dijkers, RH Medema, JWJ Lammers, L Koenderman, PJ Coffer Current Biology 10 (19), 1201-1204, 2000 | 1182 | 2000 |
| FoxM1 is required for execution of the mitotic programme and chromosome stability J Laoukili, MRH Kooistra, A Brás, J Kauw, RM Kerkhoven, A Morrison, ... Nature cell biology 7 (2), 126-136, 2005 | 731 | 2005 |
| Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27KIP1 PF Dijkers, RH Medema, C Pals, L Banerji, NSB Thomas, EWF Lam, ... Molecular and cellular biology 20 (24), 9138-9148, 2000 | 724 | 2000 |
| The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2 M Stahl, PF Dijkers, GJPL Kops, SMA Lens, PJ Coffer, BMT Burgering, ... The Journal of Immunology 168 (10), 5024-5031, 2002 | 675 | 2002 |
| Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery L Macůrek, A Lindqvist, D Lim, MA Lampson, R Klompmaker, R Freire, ... Nature 455 (7209), 119-123, 2008 | 633 | 2008 |
| FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2SIRT1 A van der Horst, LGJ Tertoolen, LMM de Vries-Smits, RA Frye, ... Journal of Biological Chemistry 279 (28), 28873-28879, 2004 | 590 | 2004 |
| The decision to enter mitosis: feedback and redundancy in the mitotic entry network A Lindqvist, V Rodríguez-Bravo, RH Medema Journal of Cell Biology 185 (2), 193-202, 2009 | 568 | 2009 |
| Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D M Schmidt, SF de Mattos, A van der Horst, R Klompmaker, GJPL Kops, ... Molecular and cellular biology 22 (22), 7842-7852, 2002 | 567 | 2002 |
| Polo-like kinase-1 is a target of the DNA damage checkpoint VAJ Smits, R Klompmaker, L Arnaud, G Rijksen, EA Nigg, RH Medema Nature cell biology 2 (9), 672-676, 2000 | 551 | 2000 |
| Shared and separate functions of polo-like kinases and aurora kinases in cancer SMA Lens, EE Voest, RH Medema Nature Reviews Cancer 10 (12), 825-841, 2010 | 546 | 2010 |
| FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines A Sunters, SF de Mattos, M Stahl, JJ Brosens, G Zoumpoulidou, ... Journal of Biological Chemistry 278 (50), 49795-49805, 2003 | 545 | 2003 |
| Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty BMT Burgering, RH Medema Journal of leukocyte biology 73 (6), 689-701, 2003 | 526 | 2003 |
| Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors GJPL Kops, RH Medema, J Glassford, MAG Essers, PF Dijkers, PJ Coffer, ... Molecular and cellular biology 22 (7), 2025-2036, 2002 | 521 | 2002 |
| Growth suppression by p16ink4 requires functional retinoblastoma protein RH Medema, RE Herrera, F Lam, RA Weinberg Proceedings of the National Academy of Sciences 92 (14), 6289-6293, 1995 | 513 | 1995 |
| Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations A Janssen, M van der Burg, K Szuhai, GJPL Kops, RH Medema Science 333 (6051), 1895-1898, 2011 | 497 | 2011 |
| Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts. EJ van Corven, PL Hordijk, RH Medema, JL Bos, WH Moolenaar Proceedings of the National Academy of Sciences 90 (4), 1257-1261, 1993 | 461 | 1993 |
