| Engineering and characterization of a superfolder green fluorescent protein JD Pédelacq, S Cabantous, TH Tran, TC Terwilliger, GS Waldo Nature biotechnology 24 (1), 79-88, 2006 | 2610 | 2006 |
| Multivalent small-molecule pan-RAS inhibitors ME Welsch, A Kaplan, JM Chambers, ME Stokes, PH Bos, A Zask, ... Cell 168 (5), 878-889. e29, 2017 | 277 | 2017 |
| Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ S Dharmaiah, L Bindu, TH Tran, WK Gillette, PH Frank, R Ghirlando, ... Proceedings of the National Academy of Sciences 113 (44), E6766-E6775, 2016 | 183 | 2016 |
| Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer GA Hobbs, NM Baker, AM Miermont, RD Thurman, M Pierobon, TH Tran, ... Cancer discovery 10 (1), 104-123, 2020 | 168 | 2020 |
| KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation TH Tran, AH Chan, LC Young, L Bindu, C Neale, S Messing, ... Nature communications 12 (1), 1176, 2021 | 159 | 2021 |
| Toxic waste disposal in Escherichia coli RB Helling, BK Janes, H Kimball, TH Tran, M Bundesmann, P Check, ... Journal of bacteriology 184 (13), 3699-3703, 2002 | 109 | 2002 |
| KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis D Rabara, TH Tran, S Dharmaiah, RM Stephens, F McCormick, ... Proceedings of the National Academy of Sciences 116 (44), 22122-22131, 2019 | 106 | 2019 |
| Discovery of new classes of compounds that reactivate acetylcholinesterase inhibited by organophosphates FS Katz, S Pecic, TH Tran, I Trakht, L Schneider, Z Zhu, L Ton‐That, ... ChemBioChem 16 (15), 2205-2215, 2015 | 83 | 2015 |
| Structural evidence of amyloid fibril formation in the putative aggregation domain of TDP-43 M Mompeán, R Hervás, Y Xu, TH Tran, C Guarnaccia, E Buratti, F Baralle, ... The journal of physical chemistry letters 6 (13), 2608-2615, 2015 | 80 | 2015 |
| Machine learning–driven multiscale modeling reveals lipid-dependent dynamics of RAS signaling proteins HI Ingólfsson, C Neale, TS Carpenter, R Shrestha, CA López, TH Tran, ... Proceedings of the National Academy of Sciences 119 (1), e2113297119, 2022 | 68 | 2022 |
| Structures of N-terminally processed KRAS provide insight into the role of N-acetylation S Dharmaiah, TH Tran, S Messing, C Agamasu, WK Gillette, W Yan, ... Scientific reports 9 (1), 10512, 2019 | 60 | 2019 |
| The small molecule BI-2852 induces a nonfunctional dimer of KRAS TH Tran, P Alexander, S Dharmaiah, C Agamasu, DV Nissley, ... Proceedings of the National Academy of Sciences 117 (7), 3363-3364, 2020 | 57 | 2020 |
| KRAS prenylation is required for bivalent binding with calmodulin in a nucleotide-independent manner C Agamasu, R Ghirlando, T Taylor, S Messing, TH Tran, L Bindu, ... Biophysical journal 116 (6), 1049-1063, 2019 | 51 | 2019 |
| Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane QN Van, CA López, M Tonelli, T Taylor, B Niu, CB Stanley, D Bhowmik, ... Proceedings of the National Academy of Sciences 117 (39), 24258-24268, 2020 | 42 | 2020 |
| LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition Q Ming, DP Celias, C Wu, AR Cole, S Singh, C Mason, S Dong, TH Tran, ... Nature immunology 23 (7), 1031-1041, 2022 | 41 | 2022 |
| Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase TH Tran, YS Hsiao, J Jo, CY Chou, LEP Dietrich, T Walz, L Tong Nature 518 (7537), 120-124, 2015 | 38 | 2015 |
| NMR signal quenching from bound biradical affinity reagents in DNP samples R Rogawski, IV Sergeyev, Y Zhang, TH Tran, Y Li, L Tong, AE McDermott The Journal of Physical Chemistry B 121 (48), 10770-10781, 2017 | 34 | 2017 |
| A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes TH Tran, K Krishnamoorthy, TP Begley, SE Ealick Acta Crystallographica Section D: Biological Crystallography 67 (10), 831-838, 2011 | 30 | 2011 |
| Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations DS Froese, F Forouhar, TH Tran, M Vollmar, YS Kim, S Lew, H Neely, ... Structure 21 (7), 1182-1192, 2013 | 20 | 2013 |
| The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases TH Tran, S Christoffersen, PW Allan, WB Parker, J Piskur, I Serra, ... Biochemistry 50 (30), 6549-6558, 2011 | 19 | 2011 |
