Jennifer Doudna
Jennifer Doudna
Professor of Molecular and Cell Biology and Chemistry, UC Berkeley
Verified email at
Cited by
Cited by
A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity
M Jinek, K Chylinski, I Fonfara, M Hauer, JA Doudna, E Charpentier
science 337 (6096), 816-821, 2012
The new frontier of genome engineering with CRISPR-Cas9
JA Doudna, E Charpentier
Science 346 (6213), 1258096, 2014
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
LS Qi, MH Larson, LA Gilbert, JA Doudna, JS Weissman, AP Arkin, ...
Cell 152 (5), 1173-1183, 2013
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
LA Gilbert, MH Larson, L Morsut, Z Liu, GA Brar, SE Torres, ...
Cell 154 (2), 442-451, 2013
CRISPR/Cas, the immune system of bacteria and archaea
P Horvath, R Barrangou
Science 327 (5962), 167-170, 2010
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
JS Chen, E Ma, LB Harrington, M Da Costa, X Tian, JM Palefsky, ...
Science 360 (6387), 436-439, 2018
RNA-programmed genome editing in human cells
M Jinek, A East, A Cheng, S Lin, E Ma, J Doudna
elife 2, e00471, 2013
RNA-guided genetic silencing systems in bacteria and archaea
B Wiedenheft, SH Sternberg, JA Doudna
Nature 482 (7385), 331-338, 2012
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
SH Sternberg, S Redding, M Jinek, EC Greene, JA Doudna
Biophysical Journal 106 (2), 695a, 2014
CRISPR–Cas9 structures and mechanisms
F Jiang, JA Doudna
Annual review of biophysics 46, 505-529, 2017
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
V Pattanayak, S Lin, JP Guilinger, E Ma, JA Doudna, DR Liu
Nature biotechnology 31 (9), 839-843, 2013
Crystal structure of a group I ribozyme domain: principles of RNA packing
JH Cate, AR Gooding, E Podell, K Zhou, BL Golden, CE Kundrot, ...
Science 273 (5282), 1678-1685, 1996
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
M Jinek, F Jiang, DW Taylor, SH Sternberg, E Kaya, E Ma, C Anders, ...
Science 343 (6176), 1247997, 2014
Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
S Lin, BT Staahl, RK Alla, JA Doudna
elife 3, e04766, 2014
Structural basis for double-stranded RNA processing by Dicer
IJ MacRae, K Zhou, F Li, A Repic, AN Brooks, WZ Cande, PD Adams, ...
Science 311 (5758), 195-198, 2006
Molecular mechanisms of RNA interference
RC Wilson, JA Doudna
Annual review of biophysics 42, 217-239, 2013
CRISPR-Cas guides the future of genetic engineering
GJ Knott, JA Doudna
Science 361 (6405), 866-869, 2018
Biology and applications of CRISPR systems: harnessing nature’s toolbox for genome engineering
AV Wright, JK Nuņez, JA Doudna
Cell 164 (1), 29-44, 2016
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
JS Chen, YS Dagdas, BP Kleinstiver, MM Welch, AA Sousa, ...
Nature 550 (7676), 407-410, 2017
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
A East-Seletsky, MR O’Connell, SC Knight, D Burstein, JHD Cate, R Tjian, ...
Nature 538 (7624), 270-273, 2016
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