| Catalytic topoisomerase II inhibitors in cancer therapy AK Larsen, AE Escargueil, A Skladanowski Pharmacology & therapeutics 99 (2), 167-181, 2003 | 532 | 2003 |
| Resistance mechanisms associated with altered intracellular distribution of anticancer agents AK Larsen, AE Escargueil, A Skladanowski Pharmacology & therapeutics 85 (3), 217-229, 2000 | 517 | 2000 |
| The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane A Garrigues, AE Escargueil, S Orlowski Proceedings of the National Academy of Sciences 99 (16), 10347-10352, 2002 | 279 | 2002 |
| Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743 DG Soares, AE Escargueil, V Poindessous, A Sarasin, A de Gramont, ... Proceedings of the National Academy of Sciences 104 (32), 13062-13067, 2007 | 198 | 2007 |
| PARPs and the DNA damage response FG Sousa, R Matuo, DG Soares, AE Escargueil, JAP Henriques, ... Carcinogenesis 33 (8), 1433-1440, 2012 | 183 | 2012 |
| Modeling the effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors A Lorz, T Lorenzi, J Clairambault, A Escargueil, B Perthame Bulletin of mathematical biology 77, 1-22, 2015 | 137 | 2015 |
| P-glycoprotein and ‘lipid rafts’: some ambiguous mutual relationships (floating on them, building them or meeting them by chance?) S Orlowski, S Martin, A Escargueil Cellular and Molecular Life Sciences CMLS 63, 1038-1059, 2006 | 137 | 2006 |
| Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, nongenetic instability, and stress-induced adaptation RH Chisholm, T Lorenzi, A Lorz, AK Larsen, LN Almeida, A Escargueil, ... Cancer research 75 (6), 930-939, 2015 | 136 | 2015 |
| What histone code for DNA repair? AE Escargueil, DG Soares, M Salvador, AK Larsen, JAP Henriques Mutation Research/Reviews in Mutation Research 658 (3), 259-270, 2008 | 133 | 2008 |
| Mitotic phosphorylation of DNA topoisomerase II α by protein kinase CK2 creates the MPM-2 phosphoepitope on Ser-1469 AE Escargueil, SY Plisov, O Filhol, C Cochet, AK Larsen Journal of Biological Chemistry 275 (44), 34710-34718, 2000 | 99 | 2000 |
| Intrinsic bevacizumab resistance is associated with prolonged activation of autocrine VEGF signaling and hypoxia tolerance in colorectal cancer cells and can be overcome by … P Mésange, V Poindessous, M Sabbah, AE Escargueil, A de Gramont, ... Oncotarget 5 (13), 4709, 2014 | 86 | 2014 |
| Trabectedin and its C subunit modified analogue PM01183 attenuate nucleotide excision repair and show activity toward platinum-resistant cells DG Soares, MS Machado, CJ Rocca, V Poindessous, D Ouaret, A Sarasin, ... Molecular cancer therapeutics 10 (8), 1481-1489, 2011 | 86 | 2011 |
| 5‐Fluorouracil and its active metabolite FdUMP cause DNA damage in human SW620 colon adenocarcinoma cell line R Matuo, FG Sousa, AE Escargueil, I Grivicich, D Garcia‐Santos, ... Journal of Applied Toxicology 29 (4), 308-316, 2009 | 83 | 2009 |
| Molecular cross-talk between the transcription, translation, and nonsense-mediated decay machineries FJ Iborra, AE Escargueil, KY Kwek, A Akoulitchev, PR Cook Journal of cell science 117 (6), 899-906, 2004 | 80 | 2004 |
| Saccharomyces cerevisiae as a model system to study the response to anticancer agents R Matuo, FG Sousa, DG Soares, D Bonatto, J Saffi, AE Escargueil, ... Cancer chemotherapy and pharmacology 70, 491-502, 2012 | 78 | 2012 |
| From DNA damage to G~ 2 arrest: the many roles of topoisomerase II AK Larsen, AE Escargueil, A Skladanowski PROGRESS IN CELL CYCLE RESEARCH. 5, 295-300, 2003 | 72 | 2003 |
| EGFR-and VEGF (R)-targeted small molecules show synergistic activity in colorectal cancer models refractory to combinations of monoclonal antibodies V Poindessous, D Ouaret, K El Ouadrani, A Battistella, VF Mégalophonos, ... Clinical Cancer Research 17 (20), 6522-6530, 2011 | 61 | 2011 |
| DNA alkylation damage and autophagy induction DL Bordin, M Lima, G Lenz, J Saffi, LB Meira, P Mesange, DG Soares, ... Mutation Research/Reviews in Mutation Research 753 (2), 91-99, 2013 | 49 | 2013 |
| Acquired irinotecan resistance is accompanied by stable modifications of cell cycle dynamics independent of MSI status A Petitprez, V Poindessous, D Ouaret, M Regairaz, G Bastian, E Guérin, ... International journal of oncology 42 (5), 1644-1653, 2013 | 43 | 2013 |
| DNA repair pathways involved in repair of lesions induced by 5-fluorouracil and its active metabolite FdUMP R Matuo, FG Sousa, AE Escargueil, DG Soares, I Grivicich, J Saffi, ... Biochemical pharmacology 79 (2), 147-153, 2010 | 41 | 2010 |
