Opposing activities protect against age-onset proteotoxicity E Cohen, J Bieschke, RM Perciavalle, JW Kelly, A Dillin Science 313 (5793), 1604-1610, 2006 | 987 | 2006 |
Reduced IGF-1 signaling delays age-associated proteotoxicity in mice E Cohen, JF Paulsson, P Blinder, T Burstyn-Cohen, D Du, G Estepa, ... Cell 139 (6), 1157-1169, 2009 | 552 | 2009 |
The insulin paradox: aging, proteotoxicity and neurodegeneration E Cohen, A Dillin Nature Reviews Neuroscience 9 (10), 759, 2008 | 348 | 2008 |
Scrapie‐like prion protein accumulates in aggresomes of cyclosporin A‐treated cells E Cohen, A Taraboulos The EMBO journal 22 (3), 404-417, 2003 | 113 | 2003 |
Temporal requirements of insulin/IGF‐1 signaling for proteotoxicity protection E Cohen, D Du, D Joyce, EA Kapernick, Y Volovik, JW Kelly, A Dillin Aging cell 9 (2), 126-134, 2010 | 97 | 2010 |
Protein quality control in health and disease T Dubnikov, T Ben-Gedalya, E Cohen Cold Spring Harbor perspectives in biology 9 (3), a023523, 2017 | 85 | 2017 |
Ageing and protein aggregation-mediated disorders: from invertebrates to mammals A Dillin, E Cohen Philosophical Transactions of the Royal Society B: Biological Sciences 366 …, 2011 | 80 | 2011 |
A novel inhibitor of the insulin/IGF signaling pathway protects from age‐onset, neurodegeneration‐linked proteotoxicity T El‐Ami, L Moll, F Carvalhal Marques, Y Volovik, H Reuveni, E Cohen Aging Cell 13 (1), 165-174, 2014 | 72 | 2014 |
Temporal requirements of heat shock factor‐1 for longevity assurance Y Volovik, M Maman, T Dubnikov, M Bejerano‐Sagie, D Joyce, ... Aging cell 11 (3), 491-499, 2012 | 66 | 2012 |
A neuronal GPCR is critical for the induction of the heat shock response in the nematode C. elegans M Maman, FC Marques, Y Volovik, T Dubnikov, M Bejerano-Sagie, ... Journal of Neuroscience 33 (14), 6102-6111, 2013 | 58 | 2013 |
Differential regulation of the heat shock factor 1 and DAF-16 by neuronal nhl-1 in the nematode C. elegans Y Volovik, L Moll, FC Marques, M Maman, M Bejerano-Sagie, E Cohen Cell reports 9 (6), 2192-2205, 2014 | 48 | 2014 |
A multi-animal tracker for studying complex behaviors E Itskovits, A Levine, E Cohen, A Zaslaver BMC biology 15 (1), 29, 2017 | 47 | 2017 |
A kinetic aggregation assay allowing selective and sensitive amyloid-β quantification in cells and tissues D Du, AN Murray, E Cohen, HE Kim, R Simkovsky, A Dillin, JW Kelly Biochemistry 50 (10), 1607-1617, 2011 | 46 | 2011 |
A kinetic assessment of the C. elegans amyloid disaggregation activity enables uncoupling of disassembly and proteolysis J Bieschke, E Cohen, A Murray, A Dillin, JW Kelly Protein Science 18 (11), 2231-2241, 2009 | 39 | 2009 |
Organismal protein homeostasis mechanisms T Hoppe, E Cohen Genetics 215 (4), 889-901, 2020 | 38 | 2020 |
The roles of cellular and organismal aging in the development of late-onset maladies F Carvalhal Marques, Y Volovik, E Cohen Annual Review of Pathology: Mechanisms of Disease 10, 1-23, 2015 | 38 | 2015 |
Cyclosporin-A-induced prion protein aggresomes are dynamic quality-control cellular compartments T Ben-Gedalya, R Lyakhovetsky, Y Yedidia, M Bejerano-Sagie, ... J Cell Sci 124 (11), 1891-1902, 2011 | 38 | 2011 |
The nematode Caenorhabditis elegans: a versatile model for the study of proteotoxicity and aging Y Volovik, FC Marques, E Cohen Methods 68 (3), 458-464, 2014 | 36 | 2014 |
Quality control compartments coming of age T Ben‐Gedalya, E Cohen Traffic 13 (5), 635-642, 2012 | 36 | 2012 |
Alzheimer's disease‐causing proline substitutions lead to presenilin 1 aggregation and malfunction T Ben‐Gedalya, L Moll, M Bejerano‐Sagie, S Frere, WA Cabral, ... The EMBO journal 34 (22), 2820-2839, 2015 | 35 | 2015 |