The hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic cardiomyopathy SN Chen, P Gurha, R Lombardi, A Ruggiero, JT Willerson, AJ Marian Circulation research 114 (3), 454-468, 2014 | 291 | 2014 |
Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction P Gurha, C Abreu-Goodger, T Wang, MO Ramirez, AL Drumond, ... Circulation 125 (22), 2751-2761, 2012 | 195 | 2012 |
Small noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder P Szafranski, AV Dharmadhikari, E Brosens, P Gurha, KE Kołodziejska, ... Genome research 23 (1), 23-33, 2013 | 139 | 2013 |
DNA damage response/TP53 pathway is activated and contributes to the pathogenesis of dilated cardiomyopathy associated with LMNA (Lamin A/C) mutations SN Chen, R Lombardi, J Karmouch, JY Tsai, G Czernuszewicz, ... Circulation research 124 (6), 856-873, 2019 | 123 | 2019 |
The Mef2 transcription network is disrupted in myotonic dystrophy heart tissue, dramatically altering miRNA and mRNA expression A Kalsotra, RK Singh, P Gurha, AJ Ward, CJ Creighton, TA Cooper Cell reports 6 (2), 336-345, 2014 | 121 | 2014 |
Classification and experimental identification of plant long non-coding RNAs MI Rai, M Alam, DA Lightfoot, P Gurha, AJ Afzal Genomics 111 (5), 997-1005, 2019 | 107 | 2019 |
Two reactions of Haloferax volcanii RNA splicing enzymes: joining of exons and circularization of introns SR Salgia, SK Singh, P Gurha, R Gupta Rna 9 (3), 319-330, 2003 | 102 | 2003 |
Cardiac fibro-adipocyte progenitors express desmosome proteins and preferentially differentiate to adipocytes upon deletion of the desmoplakin gene R Lombardi, SN Chen, A Ruggiero, P Gurha, GZ Czernuszewicz, ... Circulation research 119 (1), 41-54, 2016 | 99 | 2016 |
microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription P Gurha, T Wang, AH Larimore, Y Sassi, C Abreu-Goodger, MO Ramirez, ... PLoS One 8 (9), e75882, 2013 | 99 | 2013 |
Sequential 2′-O-methylation of archaeal pre-tRNATrp nucleotides is guided by the intron-encoded but trans-acting box C/D ribonucleoprotein of pre-tRNA SK Singh, P Gurha, EJ Tran, ES Maxwell, R Gupta Journal of Biological Chemistry 279 (46), 47661-47671, 2004 | 99 | 2004 |
Genomic reorganization of lamin-associated domains in cardiac myocytes is associated with differential gene expression and DNA methylation in human dilated cardiomyopathy SM Cheedipudi, SJ Matkovich, C Coarfa, X Hu, MJ Robertson, M Sweet, ... Circulation research 124 (8), 1198-1213, 2019 | 98 | 2019 |
MicroRNAs in cardiovascular disease P Gurha Current opinion in cardiology 31 (3), 249-254, 2016 | 95 | 2016 |
Suppression of activated FOXO transcription factors in the heart prolongs survival in a mouse model of laminopathies G Auguste, P Gurha, R Lombardi, C Coarfa, JT Willerson, AJ Marian Circulation research 122 (5), 678-692, 2018 | 67 | 2018 |
Knockdown of plakophilin 2 downregulates miR-184 through CpG hypermethylation and suppression of the E2F1 pathway and leads to enhanced adipogenesis in vitro P Gurha, X Chen, R Lombardi, JT Willerson, AJ Marian Circulation research 119 (6), 731-750, 2016 | 58 | 2016 |
Archaeal Pus10 proteins can produce both pseudouridine 54 and 55 in tRNA P Gurha, R Gupta Rna 14 (12), 2521-2527, 2008 | 56 | 2008 |
Exercise restores dysregulated gene expression in a mouse model of arrhythmogenic cardiomyopathy SM Cheedipudi, J Hu, S Fan, P Yuan, J Karmouch, G Czernuszewicz, ... Cardiovascular Research 116 (6), 1199-1213, 2020 | 54 | 2020 |
BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A/C–deficient mice G Auguste, L Rouhi, SJ Matkovich, C Coarfa, MJ Robertson, ... The Journal of clinical investigation 130 (9), 4740-4758, 2020 | 49 | 2020 |
Differential roles of archaeal box H/ACA proteins in guide RNA-dependent and independent pseudouridine formation P Gurha, A Joardar, P Chaurasia, R Gupta RNA biology 4 (2), 101-109, 2007 | 40 | 2007 |
The “guiding” principles of noncoding RNA function M Deogharia, P Gurha Wiley Interdisciplinary Reviews: RNA 13 (4), e1704, 2022 | 35 | 2022 |
Noncoding RNAs in cardiovascular diseases P Gurha Current opinion in cardiology 34 (3), 241-245, 2019 | 35 | 2019 |