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James Seckler
James Seckler
Research Scientist in Biomedical Engineering, Case Western Reserve University
Verified email at case.edu
Title
Cited by
Cited by
Year
Allosteric suppression of HIV-1 reverse transcriptase structural dynamics upon inhibitor binding
JM Seckler, MD Barkley, PL Wintrode
Biophysical journal 100 (1), 144-153, 2011
482011
Advances in D-amino acids in neurological research
JM Seckler, SJ Lewis
International journal of molecular sciences 21 (19), 7325, 2020
382020
Solution structural dynamics of HIV-1 reverse transcriptase heterodimer
JM Seckler, KJ Howard, MD Barkley, PL Wintrode
Biochemistry 48 (32), 7646-7655, 2009
372009
Voltage-gated potassium channel proteins and stereoselective S-nitroso-l-cysteine signaling
B Gaston, L Smith, J Bosch, J Seckler, D Kunze, J Kiselar, N Marozkina, ...
JCI insight 5 (18), 2020
252020
Glutathione ethyl ester reverses the deleterious effects of fentanyl on ventilation and arterial blood-gas chemistry while prolonging fentanyl-induced analgesia
MW Jenkins, F Khalid, SM Baby, WJ May, AP Young, JN Bates, F Cheng, ...
Scientific reports 11 (1), 6985, 2021
232021
d-Cystine di(m)ethyl ester reverses the deleterious effects of morphine on ventilation and arterial blood gas chemistry while promoting antinociception
B Gaston, SM Baby, WJ May, AP Young, A Grossfield, JN Bates, ...
Scientific reports 11 (1), 10038, 2021
222021
The interplay of structure and dynamics: Insights from a survey of HIV‐1 reverse transcriptase crystal structures
JM Seckler, N Leioatts, H Miao, A Grossfield
Proteins: Structure, Function, and Bioinformatics 81 (10), 1792-1801, 2013
222013
Detection of trace concentrations of S-nitrosothiols by means of a capacitive sensor
JM Seckler, NM Meyer, ST Burton, JN Bates, B Gaston, SJ Lewis
PLoS One 12 (10), e0187149, 2017
202017
Systemic administration of tempol attenuates the cardiorespiratory depressant effects of fentanyl
S Baby, R Gruber, J Discala, V Puskovic, N Jose, F Cheng, M Jenkins, ...
Frontiers in Pharmacology 12, 690407, 2021
182021
Possible roles of permafrost melting, atmospheric transport, and solar irradiance in the development of major coronavirus and influenza pandemics
AM Hofmeister, JM Seckler, GM Criss
International Journal of Environmental Research and Public Health 18 (6), 3055, 2021
182021
Nitrosyl factors play a vital role in the ventilatory depressant effects of fentanyl in unanesthetized rats
JM Seckler, A Grossfield, WJ May, PM Getsy, SJ Lewis
Biomedicine & Pharmacotherapy 146, 112571, 2022
172022
NADPH diaphorase detects S-nitrosylated proteins in aldehyde-treated biological tissues
JM Seckler, J Shen, THJ Lewis, MA Abdulameer, K Zaman, LA Palmer, ...
Scientific reports 10 (1), 21088, 2020
172020
S-nitroso-L-cysteine stereoselectively blunts the adverse effects of morphine on breathing and arterial blood gas chemistry while promoting analgesia
PM Getsy, AP Young, JN Bates, SM Baby, JM Seckler, A Grossfield, ...
Biomedicine & Pharmacotherapy 153, 113436, 2022
112022
D-cysteine ethyl ester and D-cystine dimethyl ester reverse the deleterious effects of morphine on arterial blood-gas chemistry and Alveolar-arterial gradient in anesthetized rats
PM Getsy, AP Young, A Grossfield, JM Seckler, CG Wilson, B Gaston, ...
Respiratory physiology & neurobiology 302, 103912, 2022
112022
S-Nitroso-L-Cysteine stereoselectively blunts the deleterious effects of fentanyl on breathing while augmenting antinociception in freely-moving rats
PM Getsy, SM Baby, RB Gruber, B Gaston, THJ Lewis, A Grossfield, ...
Frontiers in Pharmacology 13, 892307, 2022
92022
The ventilatory depressant actions but not the antinociceptive effects of morphine are blunted in rats receiving intravenous infusion of L-cysteine ethyl ester
THJ Lewis, WJ May, AP Young, JN Bates, SM Baby, PM Getsy, RM Ryan, ...
Biomedicine & Pharmacotherapy 156, 113939, 2022
62022
Cyclic compression increases F508 Del CFTR expression in ciliated human airway epithelium
N Marozkina, J Bosch, C Cotton, L Smith, J Seckler, K Zaman, S Rehman, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 317 (2 …, 2019
62019
Compositions and methods for stimulating ventilatory and/or respiratory drive
SJ Lewis, MW Jenkins, JM Seckler
US Patent App. 17/696,204, 2023
12023
Hypoxia releases S-nitrosocysteine from carotid body glomus cells—relevance to expression of the hypoxic ventilatory response
JM Seckler, PM Getsy, WJ May, B Gaston, SM Baby, THJ Lewis, JN Bates, ...
Frontiers in Pharmacology 14, 1250154, 2023
12023
A Novel Capacitive Biosensor for the Detection of Small Molecule S-Nitrosothiols
NM Meyer, S Burton, JN Bates, B Gaston, SJ Lewis, JM Seckler
Biophysical Journal 112 (3), 457a, 2017
12017
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