| Shedding light on the dark and weakly fluorescent states of green fluorescent proteins W Weber, V Helms, JA McCammon, PW Langhoff Proceedings of the National Academy of Sciences 96 (11), 6177-6182, 1999 | 398 | 1999 |
| The mechanism of proton exclusion in the aquaporin-1 water channel BL De Groot, T Frigato, V Helms, H Grubmüller Journal of molecular biology 333 (2), 279-293, 2003 | 308 | 2003 |
| Protein translocation across the ER membrane R Zimmermann, S Eyrisch, M Ahmad, V Helms Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (3), 912-924, 2011 | 254 | 2011 |
| Transient pockets on protein surfaces involved in protein− protein interaction S Eyrisch, V Helms Journal of medicinal chemistry 50 (15), 3457-3464, 2007 | 250 | 2007 |
| NWChem E Apra, EJ Bylaska, WA de Jong, N Govind, K Kowalski, TP Straatsma, ... American Institute of Physics, 2020 | 216 | 2020 |
| Proton shuttle in green fluorescent protein studied by dynamic simulations MA Lill, V Helms Proceedings of the National Academy of Sciences 99 (5), 2778-2781, 2002 | 159 | 2002 |
| BiP‐mediated closing of the Sec61 channel limits Ca2+ leakage from the ER N Schäuble, S Lang, M Jung, S Cappel, S Schorr, Ö Ulucan, J Linxweiler, ... The EMBO journal 31 (15), 3282-3296, 2012 | 143 | 2012 |
| Diffusional encounter of barnase and barstar A Spaar, C Dammer, RR Gabdoulline, RC Wade, V Helms Biophysical journal 90 (6), 1913-1924, 2006 | 141 | 2006 |
| Adhesive water networks facilitate binding of protein interfaces M Ahmad, W Gu, T Geyer, V Helms Nature communications 2 (1), 1-7, 2011 | 138 | 2011 |
| Atomistic simulation of water percolation and proton hopping in Nafion fuel cell membrane R Devanathan, A Venkatnathan, R Rousseau, M Dupuis, T Frigato, W Gu, ... The Journal of Physical Chemistry B 114 (43), 13681-13690, 2010 | 119 | 2010 |
| Protein dynamics tightly connected to the dynamics of surrounding and internal water molecules V Helms ChemPhysChem 8 (1), 23-33, 2007 | 116 | 2007 |
| Thermodynamics of water mediating protein-ligand interactions in cytochrome P450cam: a molecular dynamics study V Helms, RC Wade Biophysical journal 69 (3), 810-824, 1995 | 110 | 1995 |
| Dynamic water networks in cytochrome c oxidase from Paracoccus denitrificans investigated by molecular dynamics simulations E Olkhova, MC Hutter, MA Lill, V Helms, H Michel Biophysical journal 86 (4), 1873-1889, 2004 | 107 | 2004 |
| Determinants of ligand binding to cAMP-dependent protein kinase PH Hünenberger, V Helms, N Narayana, SS Taylor, JA McCammon Biochemistry 38 (8), 2358-2366, 1999 | 103 | 1999 |
| Computational alchemy to calculate absolute protein− ligand binding free energy V Helms, RC Wade Journal of the American Chemical Society 120 (12), 2710-2713, 1998 | 102 | 1998 |
| Interfering with bacterial quorum sensing K Reuter, A Steinbach, V Helms Perspectives in Medicinal Chemistry 8, PMC. S13209, 2016 | 101 | 2016 |
| Statistical analysis of predominantly transient protein–protein interfaces S Ansari, V Helms Proteins: Structure, Function, and Bioinformatics 61 (2), 344-355, 2005 | 99 | 2005 |
| A STIM2 splice variant negatively regulates store-operated calcium entry AM Miederer, D Alansary, G Schwär, PH Lee, M Jung, V Helms, ... Nature communications 6 (1), 1-12, 2015 | 98 | 2015 |
| Molecular dynamics simulation of proton transport with quantum mechanically derived proton hopping rates (Q-HOP MD) MA Lill, V Helms The Journal of Chemical Physics 115 (17), 7993-8005, 2001 | 98 | 2001 |
| NWChem: Past, present, and future E Apra, EJ Bylaska, WA De Jong, N Govind, K Kowalski, TP Straatsma, ... The Journal of chemical physics 152 (18), 184102, 2020 | 96 | 2020 |
