Follow
Diana F. Lázaro
Diana F. Lázaro
Center for Neurodegenerative Disease Research, UPenn
Verified email at pennmedicine.upenn.edu - Homepage
Title
Cited by
Cited by
Year
Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation
DF Lázaro, EF Rodrigues, R Langohr, H Shahpasandzadeh, T Ribeiro, ...
PLoS genetics 10 (11), e1004741, 2014
2022014
Glyoxal as an alternative fixative to formaldehyde in immunostaining and super‐resolution microscopy
KN Richter, NH Revelo, KJ Seitz, MS Helm, D Sarkar, RS Saleeb, E d'Este, ...
The EMBO journal 37 (1), 139-159, 2018
1722018
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons
J Pujols, S Peńa-Díaz, DF Lázaro, F Peccati, F Pinheiro, D González, ...
Proceedings of the National Academy of Sciences 115 (41), 10481-10486, 2018
1192018
Limelight on alpha-synuclein: pathological and mechanistic implications in neurodegeneration
P Wales, R Pinho, DF Lázaro, TF Outeiro
Journal of Parkinson's disease 3 (4), 415-459, 2013
1052013
The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease
RM De Oliveira, H Vicente Miranda, L Francelle, R Pinho, ÉM Szegö, ...
PLoS biology 15 (3), e2000374, 2017
1042017
Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells
R Perfeito, DF Lázaro, TF Outeiro, AC Rego
Molecular and Cellular Neuroscience 62, 51-59, 2014
922014
α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner
G Yin, TL Da Fonseca, SE Eisbach, AM Anduaga, C Breda, ML Orcellet, ...
Neurobiology of disease 70, 149-161, 2014
892014
Secretion and uptake of α-synuclein via extracellular vesicles in cultured cells
G Gustafsson, C Lööv, E Persson, DF Lázaro, S Takeda, J Bergström, ...
Cellular and molecular neurobiology 38 (8), 1539-1550, 2018
572018
C-terminal tyrosine residue modifications modulate the protective phosphorylation of serine 129 of α-synuclein in a yeast model of Parkinson's disease
A Kleinknecht, B Popova, DF Lázaro, R Pinho, O Valerius, TF Outeiro, ...
PLoS genetics 12 (6), e1006098, 2016
572016
Cellular models as tools for the study of the role of alpha-synuclein in Parkinson's disease
DF Lázaro, MAS Pavlou, TF Outeiro
Experimental neurology 298, 162-171, 2017
552017
Synucleinopathies: Where we are and where we need to go
IC Brás, A Dominguez-Meijide, E Gerhardt, D Koss, DF Lázaro, PI Santos, ...
Journal of Neurochemistry 153 (4), 433-454, 2020
522020
Small molecules detected by second-harmonic generation modulate the conformation of monomeric α-synuclein and reduce its aggregation in cells
B Moree, G Yin, DF Lázaro, F Munari, T Strohäker, K Giller, S Becker, ...
Journal of Biological Chemistry 290 (46), 27582-27593, 2015
502015
Alpha-synuclein regulates neuronal levels of manganese and calcium
T Ducic, E Carboni, B Lai, S Chen, B Michalke, DF Lázaro, TF Outeiro, ...
ACS Chemical Neuroscience 6 (10), 1769-1779, 2015
402015
Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function
I Paiva, G Jain, DF Lázaro, KG Jerčić, T Hentrich, C Kerimoglu, R Pinho, ...
Neurobiology of disease 119, 121-135, 2018
382018
The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation
DF Lázaro, MC Dias, A Carija, S Navarro, CS Madaleno, S Tenreiro, ...
Acta neuropathologica communications 4 (1), 1-15, 2016
382016
Glycation potentiates neurodegeneration in models of Huntington’s disease
H Vicente Miranda, MA Gomes, J Branco-Santos, C Breda, DF Lázaro, ...
Scientific Reports 6 (1), 1-12, 2016
292016
Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity
A Carija, F Pinheiro, J Pujols, IC Brás, DF Lázaro, C Santambrogio, ...
Redox biology 22, 101135, 2019
252019
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo
A Dominguez-Meijide, V Parrales, E Vasili, F González-Lizárraga, ...
Neurobiology of Disease 151, 105256, 2021
202021
Treatment with diphenyl–pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death
E Turriani, DF Lázaro, S Ryazanov, A Leonov, A Giese, M Schön, ...
Proceedings of the National Academy of Sciences 114 (25), E4971-E4977, 2017
192017
Protein misfolding and spreading pathology in neurodegenerative diseases
DF Lázaro, A Bellucci, P Brundin, TF Outeiro
Frontiers in Molecular Neuroscience 12, 312, 2020
162020
The system can't perform the operation now. Try again later.
Articles 1–20