| Amplification of an Esterase Gene Is Responsible for Insecticide Resistance in a California Culex Mosquito C Mouchès, N Pasteur, JB Bergé, O Hyrien, M Raymond, ... Science 233 (4765), 778-780, 1986 | 463 | 1986 |
| Transition in specification of embryonic metazoan DNA replication origins O Hyrien, C Maric, M Méchali Science 270 (5238), 994-997, 1995 | 389 | 1995 |
| Replication landscape of the human genome N Petryk, M Kahli, Y d'Aubenton-Carafa, Y Jaszczyszyn, Y Shen, M Silvain, ... Nature communications 7 (1), 10208, 2016 | 311 | 2016 |
| Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos. O Hyrien, M Mechali The EMBO journal 12 (12), 4511-4520, 1993 | 261 | 1993 |
| Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes CL Chen, A Rappailles, L Duquenne, M Huvet, G Guilbaud, L Farinelli, ... Genome research 20 (4), 447-457, 2010 | 251 | 2010 |
| Paradoxes of eukaryotic DNA replication: MCM proteins and the random completion problem O Hyrien, K Marheineke, A Goldar Bioessays 25 (2), 116-125, 2003 | 246 | 2003 |
| Characterization of amplification core and esterase B1 gene responsible for insecticide resistance in Culex. C Mouches, Y Pauplin, M Agarwal, L Lemieux, M Herzog, M Abadon, ... Proceedings of the National Academy of Sciences 87 (7), 2574-2578, 1990 | 194 | 1990 |
| Control of replication origin density and firing time in Xenopus egg extracts: role of a caffeine-sensitive, ATR-dependent checkpoint K Marheineke, O Hyrien Journal of Biological Chemistry 279 (27), 28071-28081, 2004 | 186 | 2004 |
| Dual roles of poly (dA: dT) tracts in replication initiation and fork collapse A Tubbs, S Sridharan, N van Wietmarschen, Y Maman, E Callen, ... Cell 174 (5), 1127-1142. e19, 2018 | 183 | 2018 |
| Cdc45 is a critical effector of myc-dependent DNA replication stress SV Srinivasan, D Dominguez-Sola, LC Wang, O Hyrien, J Gautier Cell reports 3 (5), 1629-1639, 2013 | 156 | 2013 |
| Evidence for sequential and increasing activation of replication origins along replication timing gradients in the human genome G Guilbaud, A Rappailles, A Baker, CL Chen, A Arneodo, A Goldar, ... PLoS computational biology 7 (12), e1002322, 2011 | 154 | 2011 |
| Plasmid replication in Xenopus eggs and egg extracts: a 2D gel electrophoretic analysis O Hyrien, M Mechali Nucleic acids research 20 (7), 1463-1469, 1992 | 144 | 1992 |
| The multicopy appearance of a large inverted duplication and the sequence at the inversion joint suggest a new model for gene amplification. O Hyrien, M Debatisse, G Buttin, BR de Saint Vincent The EMBO journal 7 (2), 407-417, 1988 | 140 | 1988 |
| Replication fork density increases during DNA synthesis in X. laevis egg extracts J Herrick, P Stanislawski, O Hyrien, A Bensimon Journal of molecular biology 300 (5), 1133-1142, 2000 | 135 | 2000 |
| Topoisomerase II can unlink replicating DNA by precatenane removal I Lucas, T Germe, M Chevrier-Miller, O Hyrien The EMBO Journal 20 (22), 6509-6519, 2001 | 131 | 2001 |
| A hotspot for novel amplification joints in a mosaic of Alu‐like repeats and palindromic A+ T‐rich DNA. O Hyrien, M Debatisse, G Buttin, BR de Saint Vincent The EMBO journal 6 (8), 2401-2408, 1987 | 125 | 1987 |
| Mechanisms and consequences of replication fork arrest O Hyrien Biochimie 82 (1), 5-17, 2000 | 120 | 2000 |
| Peaks cloaked in the mist: the landscape of mammalian replication origins O Hyrien Journal of Cell Biology 208 (2), 147-160, 2015 | 114 | 2015 |
| Mechanisms ensuring rapid and complete DNA replication despite random initiation in Xenopus early embryos I Lucas, M Chevrier-Miller, JM Sogo, O Hyrien Journal of molecular biology 296 (3), 769-786, 2000 | 114 | 2000 |
| ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells E Despras, F Daboussi, O Hyrien, K Marheineke, PL Kannouche Human molecular genetics 19 (9), 1690-1701, 2010 | 91 | 2010 |
