Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function F Luciano, A Jacquel, P Colosetti, M Herrant, S Cagnol, P Auberger Oncogene 22 (43), 6785-6793, 2003 | 578 | 2003 |
Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia L Willems, N Jacque, A Jacquel, N Neveux, T Trovati Maciel, M Lambert, ... Blood, The Journal of the American Society of Hematology 122 (20), 3521-3532, 2013 | 321 | 2013 |
Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis M Herrant, A Jacquel, S Marchetti, N Belhacene, P Colosetti, F Luciano, ... Oncogene 23 (47), 7863-7873, 2004 | 216 | 2004 |
IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential S Boulakirba, A Pfeifer, R Mhaidly, S Obba, M Goulard, T Schmitt, ... Scientific reports 8 (1), 256, 2018 | 176 | 2018 |
Autophagy is required for CSF-1–induced macrophagic differentiation and acquisition of phagocytic functions A Jacquel, S Obba, L Boyer, M Dufies, G Robert, P Gounon, E Lemichez, ... Blood, The Journal of the American Society of Hematology 119 (19), 4527-4531, 2012 | 164 | 2012 |
Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage A Jacquel, M Herrant, L Legros, N Belhacene, F Luciano, G Pages, ... The FASEB journal 17 (14), 2160-2162, 2003 | 154 | 2003 |
RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation O Fromigue, E Hay, D Modrowski, S Bouvet, A Jacquel, P Auberger, ... Cell Death & Differentiation 13 (11), 1845-1856, 2006 | 131 | 2006 |
Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells M Dufies, A Jacquel, N Belhacene, G Robert, T Cluzeau, F Luciano, ... Oncotarget 2 (11), 874, 2011 | 127 | 2011 |
Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy B Pruvot, A Jacquel, N Droin, P Auberger, D Bouscary, J Tamburini, ... haematologica 96 (4), 612, 2011 | 125 | 2011 |
Imatinib mesylate (STI571) decreases the vascular endothelial growth factor plasma concentration in patients with chronic myeloid leukemia L Legros, C Bourcier, A Jacquel, FX Mahon, JP Cassuto, P Auberger, ... Blood 104 (2), 495-501, 2004 | 120 | 2004 |
Autophagy is an important event for megakaryocytic differentiation of the chronic myelogenous leukemia K562 cell line P Colosetti, A Puissant, G Robert, F Luciano, A Jacquel, P Gounon, ... Autophagy 5 (8), 1092-1098, 2009 | 116 | 2009 |
Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo MK Tulic, E Cavazza, Y Cheli, A Jacquel, C Luci, N Cardot-Leccia, ... Nature communications 10 (1), 2178, 2019 | 114 | 2019 |
DNA damage and the activation of the p53 pathway mediate alterations in metabolic and secretory functions of adipocytes B Vergoni, PJ Cornejo, J Gilleron, M Djedaini, F Ceppo, A Jacquel, ... Diabetes 65 (10), 3062-3074, 2016 | 114 | 2016 |
Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells D Colin, E Limagne, S Jeanningros, A Jacquel, G Lizard, A Athias, ... Cancer prevention research 4 (7), 1095-1106, 2011 | 110 | 2011 |
The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML S Obba, Z Hizir, L Boyer, D Selimoglu-Buet, A Pfeifer, G Michel, ... Autophagy 11 (7), 1114-1129, 2015 | 105 | 2015 |
A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis A Jacquel, M Herrant, V Defamie, N Belhacene, P Colosetti, S Marchetti, ... Oncogene 25 (5), 781-794, 2006 | 100 | 2006 |
Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors S Grosso, A Puissant, M Dufies, P Colosetti, A Jacquel, K Lebrigand, ... Molecular cancer therapeutics 8 (7), 1924-1933, 2009 | 94 | 2009 |
p44 Mitogen-activated protein kinase (extracellular signal-regulated kinase 1)–dependent signaling contributes to epithelial skin carcinogenesis C Bourcier, A Jacquel, J Hess, I Peyrottes, P Angel, P Hofman, ... Cancer research 66 (5), 2700-2707, 2006 | 92 | 2006 |
Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia AS Green, TT Maciel, MA Hospital, C Yin, F Mazed, EC Townsend, ... Science advances 1 (8), e1500221, 2015 | 86 | 2015 |
BCL2L10 is a predictive factor for resistance to azacitidine in MDS and AML patients T Cluzeau, G Robert, N Mounier, JM Karsenti, M Dufies, A Puissant, ... Oncotarget 3 (4), 490, 2012 | 86 | 2012 |