| Retinopathy induced in mice by targeted disruption of the rhodopsin gene MM Humphries, D Rancourt, GJ Farrar, P Kenna, M Hazel, RA Bush, ... Nature genetics 15 (2), 216-219, 1997 | 640 | 1997 |
| A three-base-pair deletion in the peripherin–RDS gene in one form of retinitis pigmentosa GJ Farrar, P Kenna, SA Jordan, R Kumar-Singh, MM Humphries, ... Nature 354 (6353), 478-480, 1991 | 493 | 1991 |
| NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components SL Doyle, M Campbell, E Ozaki, RG Salomon, A Mori, PF Kenna, ... Nature medicine 18 (5), 791-798, 2012 | 466 | 2012 |
| On the genetics of retinitis pigmentosa and on mutation‐independent approaches to therapeutic intervention GJ Farrar, PF Kenna, P Humphries The EMBO journal, 2002 | 304 | 2002 |
| Autosomal dominant retinitis pigmentosa (ADRP): localization of an ADRP gene to the long arm of chromosome 3 P McWilliam, GJ Farrar, P Kenna, DG Bradley, MM Humphries, EM Sharp, ... Genomics 5 (3), 619-622, 1989 | 282 | 1989 |
| Effective delivery of large genes to the retina by dual AAV vectors I Trapani, P Colella, A Sommella, C Iodice, G Cesi, S de Simone, ... EMBO molecular medicine 6 (2), 194-211, 2014 | 259 | 2014 |
| Localizing multiple X chromosome-linked retinitis pigmentosa loci using multilocus homogeneity tests. J Ott, S Bhattacharya, JD Chen, MJ Denton, J Donald, C Dubay, GJ Farrar, ... Proceedings of the National Academy of Sciences 87 (2), 701-704, 1990 | 233 | 1990 |
| On the molecular genetics of retinitis pigmentosa P Humphries, P Kenna, GJ Farrar Science 256 (5058), 804-808, 1992 | 232 | 1992 |
| RNA interference–mediated suppression and replacement of human rhodopsin in vivo M O’Reilly, A Palfi, N Chadderton, S Millington-Ward, M Ader, T Cronin, ... The American Journal of Human Genetics 81 (1), 127-135, 2007 | 223 | 2007 |
| Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas … A Kennan, A Aherne, A Palfi, M Humphries, A McKee, A Stitt, ... Human molecular genetics 11 (5), 547-558, 2002 | 212 | 2002 |
| Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice U Bartsch, W Oriyakhel, PF Kenna, S Linke, G Richard, B Petrowitz, ... Experimental eye research 86 (4), 691-700, 2008 | 195 | 2008 |
| Suppression and replacement gene therapy for autosomal dominant disease in a murine model of dominant retinitis pigmentosa S Millington-Ward, N Chadderton, M O'reilly, A Palfi, T Goldmann, C Kilty, ... Molecular therapy 19 (4), 642-649, 2011 | 176 | 2011 |
| Improved retinal function in a mouse model of dominant retinitis pigmentosa following AAV-delivered gene therapy N Chadderton, S Millington-Ward, A Palfi, M O'reilly, G Tuohy, ... Molecular Therapy 17 (4), 593-599, 2009 | 176 | 2009 |
| Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa CJ Loscher, K Hokamp, PF Kenna, AC Ivens, P Humphries, A Palfi, ... Genome biology 8, 1-12, 2007 | 173 | 2007 |
| A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement SJ Bowne, MM Humphries, LS Sullivan, PF Kenna, L Tam, AS Kiang, ... European journal of human genetics 19 (10), 1074-1081, 2011 | 167 | 2011 |
| Retinitis pigmentosa and progressive sensorineural hearing loss caused by a C12258A mutation in the mitochondrial MTTS2 gene FC Mansergh, S Millington-Ward, A Kennan, AS Kiang, M Humphries, ... The American Journal of Human Genetics 64 (4), 971-985, 1999 | 149 | 1999 |
| CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression CM Egan, U Nyman, J Skotte, G Streubel, S Turner, DJ O’Connell, ... Developmental cell 26 (3), 223-236, 2013 | 140 | 2013 |
| Modeling and rescue of RP2 retinitis pigmentosa using iPSC-derived retinal organoids A Lane, K Jovanovic, C Shortall, D Ottaviani, AB Panes, N Schwarz, ... Stem cell reports 15 (1), 67-79, 2020 | 131 | 2020 |
| Toward a gene therapy for dominant disease: validation of an RNA interference-based mutation-independent approach AS Kiang, A Palfi, M Ader, PF Kenna, S Millington-Ward, G Clark, ... Molecular Therapy 12 (3), 555-561, 2005 | 124 | 2005 |
| A novel mutation within the rhodopsin gene (Thr‐94‐Ile) causing autosomal dominant congenital stationary night blindness N al‐Jandal, GJ Farrar, AS Kiang, MM Humphries, N Bannon, ... Human mutation 13 (1), 75-81, 1999 | 124 | 1999 |
