| Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation LV Sinclair, J Rolf, E Emslie, YB Shi, PM Taylor, DA Cantrell Nature immunology 14 (5), 500-508, 2013 | 873 | 2013 |
| PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells DK Finlay, E Rosenzweig, LV Sinclair, C Feijoo-Carnero, JL Hukelmann, ... Journal of Experimental Medicine 209 (13), 2441-2453, 2012 | 624 | 2012 |
| Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking LV Sinclair, D Finlay, C Feijoo, GH Cornish, A Gray, A Ager, K Okkenhaug, ... Nature immunology 9 (5), 513-521, 2008 | 443 | 2008 |
| Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking LV Sinclair, D Finlay, C Feijoo, GH Cornish, A Gray, A Ager, K Okkenhaug, ... Nature immunology 9 (5), 513-521, 2008 | 443 | 2008 |
| Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy M Swamy, S Pathak, KM Grzes, S Damerow, LV Sinclair, DMF Van Aalten, ... Nature immunology 17 (6), 712-720, 2016 | 317 | 2016 |
| Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy M Swamy, S Pathak, KM Grzes, S Damerow, LV Sinclair, DMF Van Aalten, ... Nature immunology 17 (6), 712-720, 2016 | 317 | 2016 |
| Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism AN Macintyre, D Finlay, G Preston, LV Sinclair, CM Waugh, P Tamas, ... Immunity 34 (2), 224-236, 2011 | 293 | 2011 |
| Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells LJ Pallett, US Gill, A Quaglia, LV Sinclair, M Jover-Cobos, A Schurich, ... Nature medicine 21 (6), 591-600, 2015 | 292 | 2015 |
| Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice RM Loftus, N Assmann, N Kedia-Mehta, KL O’Brien, A Garcia, C Gillespie, ... Nature communications 9 (1), 2341, 2018 | 288 | 2018 |
| The cytotoxic T cell proteome and its shaping by the kinase mTOR JL Hukelmann, KE Anderson, LV Sinclair, KM Grzes, AB Murillo, ... Nature immunology 17 (1), 104-112, 2016 | 235 | 2016 |
| The cytotoxic T cell proteome and its shaping by the kinase mTOR JL Hukelmann, KE Anderson, LV Sinclair, KM Grzes, AB Murillo, ... Nature immunology 17 (1), 104-112, 2016 | 235 | 2016 |
| Differential regulation of T-cell growth by IL-2 and IL-15 GH Cornish, LV Sinclair, DA Cantrell Blood 108 (2), 600-608, 2006 | 202 | 2006 |
| Differential regulation of T-cell growth by IL-2 and IL-15 GH Cornish, LV Sinclair, DA Cantrell Blood 108 (2), 600-608, 2006 | 202 | 2006 |
| Single cell tuning of Myc expression by antigen receptor signal strength and interleukin‐2 in T lymphocytes GC Preston, LV Sinclair, A Kaskar, JL Hukelmann, MN Navarro, I Ferrero, ... The EMBO journal 34 (15), 2008-2024, 2015 | 162 | 2015 |
| Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation JM Marchingo, LV Sinclair, AJM Howden, DA Cantrell Elife 9, e53725, 2020 | 159 | 2020 |
| Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation AJM Howden, JL Hukelmann, A Brenes, L Spinelli, LV Sinclair, ... Nature immunology 20 (11), 1542-1554, 2019 | 159 | 2019 |
| Antigen receptor control of methionine metabolism in T cells LV Sinclair, AJM Howden, A Brenes, L Spinelli, JL Hukelmann, ... Elife 8, e44210, 2019 | 151 | 2019 |
| Single cell analysis of kynurenine and System L amino acid transport in T cells LV Sinclair, D Neyens, G Ramsay, PM Taylor, DA Cantrell Nature communications 9 (1), 1981, 2018 | 144 | 2018 |
| Glucose represses dendritic cell-induced T cell responses SJ Lawless, N Kedia-Mehta, JF Walls, R McGarrigle, O Convery, ... Nature communications 8 (1), 15620, 2017 | 142 | 2017 |
| Phosphoinositide (3, 4, 5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not … C Waugh, L Sinclair, D Finlay, JR Bayascas, D Cantrell Molecular and cellular biology 29 (21), 5952-5962, 2009 | 101 | 2009 |
