Ludovic Vallier
Ludovic Vallier
Cambridge University and Wellcome Trust Sanger Institute
Verified email at
Cited by
Cited by
Derivation of pluripotent epiblast stem cells from mammalian embryos
IGM Brons, LE Smithers, MWB Trotter, P Rugg-Gunn, B Sun, ...
Nature 448 (7150), 191-195, 2007
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
W Sungnak, N Huang, C Bécavin, M Berg, R Queen, M Litvinukova, ...
Nature medicine 26 (5), 681-687, 2020
Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells
L Vallier, M Alexander, RA Pedersen
Journal of cell science 118 (19), 4495-4509, 2005
Targeted gene correction of α 1-antitrypsin deficiency in induced pluripotent stem cells
K Yusa, ST Rashid, H Strick-Marchand, I Varela, PQ Liu, DE Paschon, ...
Nature 478 (7369), 391-394, 2011
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells
ST Rashid, S Corbineau, N Hannan, SJ Marciniak, E Miranda, ...
The Journal of clinical investigation 120 (9), 3127-3136, 2010
Senescence impairs successful reprogramming to pluripotent stem cells
A Banito, ST Rashid, JC Acosta, SD Li, CF Pereira, I Geti, S Pinho, ...
Genes & development 23 (18), 2134-2139, 2009
Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development
T Touboul, NRF Hannan, S Corbineau, A Martinez, C Martinet, ...
Hepatology 51 (5), 1754-1765, 2010
The cell-cycle state of stem cells determines cell fate propensity
S Pauklin, L Vallier
Cell 155 (1), 135-147, 2013
Activin/Nodal signalling maintains pluripotency by controlling Nanog expression
L Vallier, S Mendjan, S Brown, Z Chng, A Teo, LE Smithers, MWB Trotter, ...
Oxford University Press for The Company of Biologists Limited 136 (8), 1339-1349, 2009
Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway
L Vallier, D Reynolds, RA Pedersen
Developmental biology 275 (2), 403-421, 2004
Common genetic variation drives molecular heterogeneity in human iPSCs
H Kilpinen, A Goncalves, A Leha, V Afzal, K Alasoo, S Ashford, S Bala, ...
Nature 546 (7658), 370-375, 2017
Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm
JR Smith, L Vallier, G Lupo, M Alexander, WA Harris, RA Pedersen
Developmental biology 313 (1), 107-117, 2008
Pluripotency factors regulate definitive endoderm specification through eomesodermin
AKK Teo, SJ Arnold, MWB Trotter, S Brown, LT Ang, Z Chng, ...
Genes & development 25 (3), 238-250, 2011
Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways
L Vallier, T Touboul, Z Chng, M Brimpari, N Hannan, E Millan, ...
PloS one 4 (6), e6082, 2009
Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury
RP Fordham, S Yui, NRF Hannan, C Soendergaard, A Madgwick, ...
Cell stem cell 13 (6), 734-744, 2013
Production of hepatocyte-like cells from human pluripotent stem cells
NRF Hannan, CP Segeritz, T Touboul, L Vallier
Nature protocols 8 (2), 430-437, 2013
Genome editing reveals a role for OCT4 in human embryogenesis
NME Fogarty, A McCarthy, KE Snijders, BE Powell, N Kubikova, ...
Nature 550 (7674), 67-73, 2017
Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes
M Baxter, S Withey, S Harrison, CP Segeritz, F Zhang, R Atkinson-Dell, ...
Journal of hepatology 62 (3), 581-589, 2015
Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
F Sampaziotis, MC De Brito, P Madrigal, A Bertero, K Saeb-Parsy, ...
Nature biotechnology 33 (8), 845-852, 2015
Genetic background drives transcriptional variation in human induced pluripotent stem cells
F Rouhani, N Kumasaka, MC de Brito, A Bradley, L Vallier, D Gaffney
PLoS genetics 10 (6), e1004432, 2014
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