Idan Frumkin
Idan Frumkin
Postdoctoral fellow, Department of Biology, MIT
Verified email at
Cited by
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Codon usage of highly expressed genes affects proteome-wide translation efficiency
I Frumkin, MJ Lajoie, CJ Gregg, G Hornung, GM Church, Y Pilpel
Proceedings of the National Academy of Sciences 115 (21), E4940-E4949, 2018
Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes
K Krumpe*, I Frumkin*, et al, (*equal contribution)
Molecular biology of the cell 23 (20), 3927-3935, 2012
tRNA genes rapidly change in evolution to meet novel translational demands
AH Yona*, Z Bloom-Ackermann*, I Frumkin*, et al, (*equal contribution)
Elife 2, e01339, 2013
Mitochondrial 16S rRNA is methylated by tRNA methyltransferase TRMT61B in all vertebrates
D Bar-Yaacov, I Frumkin, Y Yashiro, T Chujo, Y Ishigami, Y Chemla, ...
PLoS biology 14 (9), e1002557, 2016
Gene Architectures that Minimize Cost of Gene Expression
I Frumkin*, D Schirman*, A Rotman*, et al, (*equal contribution)
Molecular Cell 65 (1), 142-153, 2017
A relay race on the evolutionary adaptation spectrum
AH Yona, I Frumkin, Y Pilpel
Cell 163 (3), 549-559, 2015
The yeast ER-intramembrane protease Ypf1 refines nutrient sensing by regulating transporter abundance
D Avci, S Fuchs, B Schrul, A Fukumori, M Breker, I Frumkin, C Chen, ...
Molecular cell 56 (5), 630-640, 2014
Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest
N Aharon-Hefetz, I Frumkin, Y Mayshar, O Dahan, Y Pilpel, R Rak
Elife 9, e58461, 2020
Evolution of intron splicing towards optimized gene expression is based on various Cis- and Trans-molecular mechanisms
I Frumkin, I Yofe, R Bar-Ziv, Y Gurvich, YY Lu, Y Voichek, R Towers, ...
PLoS biology 17 (8), e3000423, 2019
Selection of a de novo gene that can promote survival of Escherichiacoli by modulating protein homeostasis pathways
I Frumkin, MT Laub
Nature Ecology & Evolution 7 (12), 2067-2079, 2023
Does cancer strive to minimize the cost of gene expression?
D Schirman, I Frumkin, Y Pilpel
Oncotarget 9 (46), 27909, 2018
Elucidating evolutionary and regulatory mechanisms of cellular machineries of the central dogma
I Frumkin
Weizmann Institute of Science, 0
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