Basak Uygun
Basak Uygun
Associate Professor of Surgery at Massachusetts General Hospital, Harvard Medical School, Shriners
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Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix
BE Uygun, A Soto-Gutierrez, H Yagi, ML Izamis, MA Guzzardi, C Shulman, ...
Nature medicine 16 (7), 814-820, 2010
Supercooling enables long-term transplantation survival following 4 days of liver preservation
TA Berendsen, BG Bruinsma, CF Puts, N Saeidi, OB Usta, BE Uygun, ...
Nature medicine 20 (7), 790-793, 2014
Subnormothermic machine perfusion at both 20 C and 30 C recovers ischemic rat livers for successful transplantation
H Tolboom, ML Izamis, N Sharma, JM Milwid, B Uygun, F Berthiaume, ...
Journal of Surgical Research 175 (1), 149-156, 2012
Proteomic analysis of naturally-sourced biological scaffolds
Q Li, BE Uygun, S Geerts, S Ozer, M Scalf, SE Gilpin, HC Ott, ML Yarmush, ...
Biomaterials 75, 37-46, 2016
Effects of immobilized glycosaminoglycans on the proliferation and differentiation of mesenchymal stem cells
BE Uygun, SE Stojsih, HWT Matthew
Tissue Engineering Part A 15 (11), 3499-3512, 2009
Tissue heterogeneity in structure and conductivity contribute to cell survival during irreversible electroporation ablation by “electric field sinks”
A Golberg, BG Bruinsma, BE Uygun, ML Yarmush
Scientific reports 5 (1), 1-7, 2015
Cell delivery: from cell transplantation to organ engineering
A Soto-Gutierrez, H Yagi, BE Uygun, N Navarro-Alvarez, K Uygun, ...
Cell transplantation 19 (6-7), 655-665, 2010
Application of whole-organ tissue engineering in hepatology
BE Uygun, ML Yarmush, K Uygun
Nature reviews Gastroenterology & hepatology 9 (12), 738-744, 2012
Co-delivery of a growth factor and a tissue-protective molecule using elastin biopolymers accelerates wound healing in diabetic mice
J Devalliere, K Dooley, Y Hu, SS Kelangi, BE Uygun, ML Yarmush
Biomaterials 141, 149-160, 2017
Decellularized human liver extracellular matrix (hDLM)‐mediated hepatic differentiation of human induced pluripotent stem cells (hIPSCs)
M Jaramillo, H Yeh, ML Yarmush, BE Uygun
Journal of tissue engineering and regenerative medicine 12 (4), e1962-e1973, 2018
Decellularization and recellularization of whole livers
BE Uygun, G Price, N Saeidi, ML Izamis, T Berendsen, M Yarmush, ...
JoVE (Journal of Visualized Experiments), e2394, 2011
Layer-by-layer heparinization of decellularized liver matrices to reduce thrombogenicity of tissue engineered grafts
BG Bruinsma, Y Kim, TA Berendsen, S Ozer, ML Yarmush, BE Uygun
Journal of clinical and translational research 1 (1), 48, 2015
Perfusion defatting at subnormothermic temperatures in steatotic rat livers
Q Liu, T Berendsen, ML Izamis, B Uygun, ML Yarmush, K Uygun
Transplantation proceedings 45 (9), 3209-3213, 2013
Improving functional re-endothelialization of acellular liver scaffold using REDV cell-binding domain
J Devalliere, Y Chen, K Dooley, ML Yarmush, BE Uygun
Acta biomaterialia 78, 151-164, 2018
A metabolic index of ischemic injury for perfusion-recovery of cadaveric rat livers
S Perk, ML Izamis, H Tolboom, B Uygun, F Berthiaume, ML Yarmush, ...
PLoS One 6 (12), e28518, 2011
Resuscitation of ischemic donor livers with normothermic machine perfusion: a metabolic flux analysis of treatment in rats
ML Izamis, H Tolboom, B Uygun, F Berthiaume, ML Yarmush, K Uygun
PLoS One 8 (7), e69758, 2013
Nuclear receptors control pro-viral and antiviral metabolic responses to hepatitis C virus infection
G Levy, N Habib, MA Guzzardi, D Kitsberg, D Bomze, E Ezra, BE Uygun, ...
Nature chemical biology 12 (12), 1037-1045, 2016
Functional human liver preservation and recovery by means of subnormothermic machine perfusion
BG Bruinsma, JH Avruch, PD Weeder, GV Sridharan, BE Uygun, ...
JoVE (Journal of Visualized Experiments), e52777, 2015
Supercooling as a viable non-freezing cell preservation method of rat hepatocytes
OB Usta, Y Kim, S Ozer, BG Bruinsma, J Lee, E Demir, TA Berendsen, ...
PloS one 8 (7), e69334, 2013
High throughput single cell bioinformatics
KL Roach, KR King, BE Uygun, IS Kohane, ML Yarmush, M Toner
Biotechnology progress 25 (6), 1772-1779, 2009
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