DJ-1 is a redox-dependent molecular chaperone that inhibits α-synuclein aggregate formation S Shendelman, A Jonason, C Martinat, T Leete, A Abeliovich PLoS biology 2 (11), e362, 2004 | 744 | 2004 |
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity JF Staropoli, C McDermott, C Martinat, B Schulman, E Demireva, ... Neuron 37 (5), 735-749, 2003 | 497 | 2003 |
Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes Y Maury, J Côme, RA Piskorowski, N Salah-Mohellibi, V Chevaleyre, ... Nature biotechnology 33 (1), 89-96, 2015 | 381 | 2015 |
Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES-derived cell model of primary Parkinsonism C Martinat, S Shendelman, A Jonason, T Leete, MF Beal, L Yang, T Floss, ... PLoS biology 2 (11), e327, 2004 | 355 | 2004 |
Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype C Martinat, JJ Bacci, T Leete, J Kim, WB Vanti, AH Newman, JH Cha, ... Proceedings of the National Academy of Sciences 103 (8), 2874-2879, 2006 | 268 | 2006 |
Translation of expanded CGG repeats into FMRpolyG is pathogenic and may contribute to fragile X tremor ataxia syndrome C Sellier, RAM Buijsen, F He, S Natla, L Jung, P Tropel, A Gaucherot, ... Neuron 93 (2), 331-347, 2017 | 215 | 2017 |
Erosion of X chromosome inactivation in human pluripotent cells initiates with XACT coating and depends on a specific heterochromatin landscape C Vallot, JF Ouimette, M Makhlouf, O Féraud, J Pontis, J Côme, C Martinat, ... Cell stem cell 16 (5), 533-546, 2015 | 155 | 2015 |
Unique preservation of neural cells in Hutchinson-Gilford progeria syndrome is due to the expression of the neural-specific miR-9 microRNA X Nissan, S Blondel, C Navarro, Y Maury, C Denis, M Girard, C Martinat, ... Cell reports 2 (1), 1-9, 2012 | 135 | 2012 |
Mutant human embryonic stem cells reveal neurite and synapse formation defects in type 1 myotonic dystrophy A Marteyn, Y Maury, MM Gauthier, C Lecuyer, R Vernet, JA Denis, G Pietu, ... Cell stem cell 8 (4), 434-444, 2011 | 123 | 2011 |
Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers P Frick, C Sellier, IRA Mackenzie, CY Cheng, J Tahraoui-Bories, ... Acta neuropathologica communications 6, 1-17, 2018 | 119 | 2018 |
Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy RA Powis, E Karyka, P Boyd, J Côme, RA Jones, Y Zheng, E Szunyogova, ... JCI insight 1 (11), 2016 | 92 | 2016 |
In vitro and in vivo modulation of alternative splicing by the biguanide metformin D Laustriat, J Gide, L Barrault, E Chautard, C Benoit, D Auboeuf, A Boland, ... Molecular Therapy-Nucleic Acids 4, 2015 | 91 | 2015 |
High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes J Charbord, P Poydenot, C Bonnefond, M Feyeux, F Casagrande, ... Stem Cells 31 (9), 1816-1828, 2013 | 83 | 2013 |
Human pluripotent stem cells for disease modelling and drug screening Y Maury, M Gauthier, M Peschanski, C Martinat Bioessays 34 (1), 61-71, 2012 | 81 | 2012 |
Moving towards treatments for spinal muscular atrophy: hopes and limits B Wirth, M Barkats, C Martinat, M Sendtner, TH Gillingwater Expert opinion on emerging drugs 20 (3), 353-356, 2015 | 74 | 2015 |
The future of regenerative medicine: cell therapy using pluripotent stem cells and acellular therapies based on extracellular vesicles M Jarrige, E Frank, E Herardot, S Martineau, A Darle, M Benabides, ... Cells 10 (2), 240, 2021 | 63 | 2021 |
Induced pluripotent stem cells reveal functional differences between drugs currently investigated in patients with hutchinson-gilford progeria syndrome S Blondel, AL Jaskowiak, AL Egesipe, A Le Corf, C Navarro, V Cordette, ... Stem cells translational medicine 3 (4), 510-519, 2014 | 60 | 2014 |
Interaction of Theiler’s virus with intermediate filaments of infected cells P Nédellec, P Vicart, C Laurent-Winter, C Martinat, MC Prévost, M Brahic Journal of virology 72 (12), 9553-9560, 1998 | 60 | 1998 |
mTOR-dependent proliferation defect in human ES-derived neural stem cells affected by myotonic dystrophy type 1 JA Denis, M Gauthier, L Rachdi, S Aubert, K Giraud-Triboult, P Poydenot, ... Journal of Cell Science 126 (8), 1763-1772, 2013 | 56 | 2013 |
Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification V Mouilleau, C Vaslin, R Robert, S Gribaudo, N Nicolas, M Jarrige, ... Development 148 (6), dev194514, 2021 | 43 | 2021 |