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Merve Cakir
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583 (7816), 459-468, 2020
43962020
The global phosphorylation landscape of SARS-CoV-2 infection
M Bouhaddou, D Memon, B Meyer, KM White, VV Rezelj, MC Marrero, ...
Cell 182 (3), 685-712. e19, 2020
8722020
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
6202020
Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors
GR Anderson, SE Wardell, M Cakir, C Yip, Y Ahn, M Ali, AP Yllanes, ...
Nature Communications 9 (1), 1677, 2018
1222018
Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity
RS Soderquist, L Crawford, E Liu, M Lu, A Agarwal, GR Anderson, KH Lin, ...
Nature communications 9 (1), 3513, 2018
1102018
A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution
GR Anderson, PS Winter, KH Lin, DP Nussbaum, M Cakir, EM Stein, ...
Cell Reports 20 (4), 999-1015, 2017
952017
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation
GR Anderson, SE Wardell, M Cakir, L Crawford, JC Leeds, DP Nussbaum, ...
Science Translational Medicine 8 (369), 369ra175-369ra175, 2016
612016
The landscape of human cancer proteins targeted by SARS-CoV-2
B Tutuncuoglu, M Cakir, J Batra, M Bouhaddou, M Eckhardt, DE Gordon, ...
Cancer discovery 10 (7), 916-921, 2020
442020
Integrating biological pathways and genomic profiles with ChiBE 2
Ö Babur, U Dogrusoz, M Çakır, BA Aksoy, N Schultz, C Sander, E Demir
BMC genomics 15 (1), 1-9, 2014
322014
Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models
MT Manzari, GR Anderson, KH Lin, RS Soderquist, M Çakir, M Zhang, ...
Science Advances 5 (9), eaaw9162, 2019
132019
Target Discovery for Host-Directed Antiviral Therapies: Application of Proteomics Approaches
M Cakir, K Obernier, A Forget, NJ Krogan
mSystems 6 (5), e00388-21, 2021
102021
A foundational atlas of autism protein interactions reveals molecular convergence
B Wang, R Vartak, Y Zaltsman, ZZC Naing, K Hennick, B Polacco, ...
32023
Label propagation defines signaling networks associated with recurrently mutated cancer genes
M Cakir, S Mukherjee, KC Wood
Scientific reports 9 (1), 1-18, 2019
22019
Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS-Mutant Cancers
DP Nussbaum, CA Martz, AM Waters, A Barrera, JC Rutter, ...
bioRxiv, 2022
12022
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