| Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis A Sierra, JM Encinas, JJP Deudero, JH Chancey, G Enikolopov, ... Cell stem cell 7 (4), 483-495, 2010 | 1777 | 2010 |
| p53 opens the mitochondrial permeability transition pore to trigger necrosis AV Vaseva, ND Marchenko, K Ji, SE Tsirka, S Holzmann, UM Moll Cell 149 (7), 1536-1548, 2012 | 803 | 2012 |
| Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator SE Tsirka, A Gualandris, DG Amaral, S Strickland Nature 377 (6547), 340-344, 1995 | 798 | 1995 |
| Tissue plasminogen activator (tPA) increase neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice YF Wang, SE Tsirka, S Strickland, PE Stieg, SG Soriano, SA Lipton Nature medicine 4 (2), 228-231, 1998 | 797 | 1998 |
| An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus SE Tsirka, AD Rogove, TH Bugge, JL Degen, S Strickland Journal of Neuroscience 17 (2), 543-552, 1997 | 520 | 1997 |
| Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage J Wang, SE Tsirka Brain 128 (7), 1622-1633, 2005 | 382 | 2005 |
| Microglia actively regulate the number of functional synapses K Ji, G Akgul, LP Wollmuth, SE Tsirka PloS one 8 (2), e56293, 2013 | 329 | 2013 |
| Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) MW Elmes, M Kaczocha, WT Berger, KN Leung, BP Ralph, L Wang, ... Journal of Biological Chemistry 290 (14), 8711-8721, 2015 | 322 | 2015 |
| Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II CJ Siao, SE Tsirka Journal of Neuroscience 22 (9), 3352-3358, 2002 | 273 | 2002 |
| Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator A Gualandris, TE Jones, S Strickland, SE Tsirka Journal of Neuroscience 16 (7), 2220-2225, 1996 | 271 | 1996 |
| Microglia/macrophages promote glioma progression H Zhai, FL Heppner, SE Tsirka Glia 59 (3), 472-485, 2011 | 255 | 2011 |
| Neuronal cell death and tPA SE Tsirka, AD Rogove, S Strickland Nature 384 (6605), 123-124, 1996 | 252 | 1996 |
| The tissue plasminogen activator (tPA/Plasmin) extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate YP Wu, CJ Siao, W Lu, TC Sung, MA Frohman, P Milev, TH Bugge, ... The Journal of cell biology 148 (6), 1295-1304, 2000 | 215 | 2000 |
| Protective role of tuftsin fragment 1‐3 in an animal model of intracerebral hemorrhage J Wang, AD Rogove, AE Tsirka, SE Tsirka Annals of Neurology: Official Journal of the American Neurological …, 2003 | 212 | 2003 |
| Brain edema after intracerebral hemorrhage: mechanisms, treatment options, management strategies, and operative indications R Thiex, SE Tsirka Neurosurgical focus 22 (5), 1-7, 2007 | 196 | 2007 |
| Neurotoxic responses by microglia elicited by excitotoxic injury in the mouse hippocampus AD Rogove, SE Tsirka Current Biology 8 (1), 19-25, 1998 | 192 | 1998 |
| Monocyte chemoattractant protein-1 and the blood–brain barrier Y Yao, SE Tsirka Cellular and molecular life sciences 71, 683-697, 2014 | 187 | 2014 |
| Tuftsin fragment 1–3 is beneficial when delivered after the induction of intracerebral hemorrhage J Wang, SE Tsirka Stroke 36 (3), 613-618, 2005 | 187 | 2005 |
| Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system AD Rogove, CJ Siao, B Keyt, S Strickland, SE Tsirka Journal of cell science 112 (22), 4007-4016, 1999 | 185 | 1999 |
| Cell-culture models of the blood–brain barrier Y He, Y Yao, SE Tsirka, Y Cao Stroke 45 (8), 2514-2526, 2014 | 176 | 2014 |
