| Association between mitochondrial dysfunction and severity and outcome of septic shock D Brealey, M Brand, I Hargreaves, S Heales, J Land, R Smolenski, ... The Lancet 360 (9328), 219-223, 2002 | 1730 | 2002 |
| Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit RM Venn, CJ Bradshaw, R Spencer, D Brealey, E Caudwell, C Naughton, ... Anaesthesia 54 (12), 1136-1142, 1999 | 783 | 1999 |
| Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 724 | 2021 |
| Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure D Brealey, S Karyampudi, TS Jacques, M Novelli, R Stidwill, V Taylor, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2004 | 575 | 2004 |
| Levosimendan for the prevention of acute organ dysfunction in sepsis AC Gordon, GD Perkins, M Singer, DF McAuley, RML Orme, ... New England Journal of Medicine 375 (17), 1638-1648, 2016 | 330 | 2016 |
| Preoperative intravenous iron to treat anaemia before major abdominal surgery (PREVENTT): a randomised, double-blind, controlled trial T Richards, RR Baikady, B Clevenger, A Butcher, S Abeysiri, M Chau, ... The Lancet 396 (10259), 1353-1361, 2020 | 264 | 2020 |
| Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study P Sinha, CS Calfee, S Cherian, D Brealey, S Cutler, C King, C Killick, ... The Lancet Respiratory Medicine 8 (12), 1209-1218, 2020 | 217 | 2020 |
| Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study RK Gupta, EM Harrison, A Ho, AB Docherty, SR Knight, M van Smeden, ... The Lancet Respiratory Medicine 9 (4), 349-359, 2021 | 208 | 2021 |
| Rapid diagnosis of infection in the critically ill, a multicenter study of molecular detection in bloodstream infections, pneumonia, and sterile site infections JL Vincent, D Brealey, N Libert, NE Abidi, M O’Dwyer, K Zacharowski, ... Critical care medicine 43 (11), 2283-2291, 2015 | 187 | 2015 |
| Mitochondrial dysfunction in sepsis M Singer, D Brealey Biochemical Society Symposia 66, 149-166, 1999 | 183 | 1999 |
| Mitochondrial dysfunction in sepsis D Brealey, M Singer Current infectious disease reports 5 (5), 365-371, 2003 | 182 | 2003 |
| Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the … CI Bloom, TM Drake, AB Docherty, BJ Lipworth, SL Johnston, ... The Lancet Respiratory Medicine 9 (7), 699-711, 2021 | 164 | 2021 |
| Effect of human recombinant alkaline phosphatase on 7-day creatinine clearance in patients with sepsis-associated acute kidney injury: a randomized clinical trial P Pickkers, RL Mehta, PT Murray, M Joannidis, BA Molitoris, JA Kellum, ... Jama 320 (19), 1998-2009, 2018 | 147 | 2018 |
| Hyperglycemia in critical illness: a review D Brealey, M Singer Journal of diabetes science and technology 3 (6), 1250-1260, 2009 | 146 | 2009 |
| Effect of lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal vs standard care ventilation on 90-day mortality in patients with acute hypoxemic … JJ McNamee, MA Gillies, NA Barrett, GD Perkins, W Tunnicliffe, D Young, ... Jama 326 (11), 1013-1023, 2021 | 144 | 2021 |
| Effect of intravenous interferon β-1a on death and days free from mechanical ventilation among patients with moderate to severe acute respiratory distress syndrome: a … VM Ranieri, V Pettilä, MK Karvonen, J Jalkanen, P Nightingale, D Brealey, ... Jama 323 (8), 725-733, 2020 | 137 | 2020 |
| Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind … T Welte, RP Dellinger, H Ebelt, M Ferrer, SM Opal, M Singer, JL Vincent, ... Intensive care medicine 44, 438-448, 2018 | 124 | 2018 |
| Mitochondrial dysfunction in patients with severe sepsis: an EPR interrogation of individual respiratory chain components DA Svistunenko, N Davies, D Brealey, M Singer, CE Cooper Biochimica Et Biophysica Acta (BBA)-Bioenergetics 1757 (4), 262-272, 2006 | 124 | 2006 |
| Evidence for chemokine synergy during neutrophil migration in ARDS AE Williams, RJ José, PF Mercer, D Brealey, D Parekh, DR Thickett, ... Thorax 72 (1), 66-73, 2017 | 110 | 2017 |
| Effect of intermittent or continuous feed on muscle wasting in critical illness: a phase 2 clinical trial AS McNelly, DE Bear, BA Connolly, G Arbane, L Allum, A Tarbhai, ... Chest 158 (1), 183-194, 2020 | 106 | 2020 |
