| Genomic instability in laminopathy-based premature aging B Liu, J Wang, KM Chan, WM Tjia, W Deng, X Guan, J Huang, KM Li, ... Nature medicine 11 (7), 780-785, 2005 | 729 | 2005 |
| Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice V Krishnan, MZY Chow, Z Wang, L Zhang, B Liu, X Liu, Z Zhou Proceedings of the National Academy of Sciences 108 (30), 12325-12330, 2011 | 256 | 2011 |
| Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient mice Z Zhou, J Wang, R Cao, H Morita, R Soininen, KM Chan, B Liu, Y Cao, ... Cancer research 64 (14), 4699-4702, 2004 | 252 | 2004 |
| Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria B Liu, S Ghosh, X Yang, H Zheng, X Liu, Z Wang, G Jin, B Zheng, ... Cell metabolism 16 (6), 738-750, 2012 | 217 | 2012 |
| SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis X Tang, L Shi, N Xie, Z Liu, M Qian, F Meng, Q Xu, M Zhou, X Cao, ... Nature communications 8 (1), 318, 2017 | 185 | 2017 |
| Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model B Liu, Z Wang, L Zhang, S Ghosh, H Zheng, Z Zhou Nature communications 4 (1), 1868, 2013 | 150 | 2013 |
| Lamin A is an endogenous SIRT6 activator and promotes SIRT6-mediated DNA repair S Ghosh, B Liu, Y Wang, Q Hao, Z Zhou Cell reports 13 (7), 1396-1406, 2015 | 123 | 2015 |
| Biomarkers of aging Aging Biomarker Consortium, H Bao, J Cao, M Chen, M Chen, W Chen, ... Science China Life Sciences 66 (5), 893-1066, 2023 | 107* | 2023 |
| SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair M Tang, Z Li, C Zhang, X Lu, B Tu, Z Cao, Y Li, Y Chen, L Jiang, H Wang, ... Science advances 5 (3), eaav1118, 2019 | 102 | 2019 |
| Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming Y Wu, Y Li, H Zhang, Y Huang, P Zhao, Y Tang, X Qiu, Y Ying, W Li, S Ni, ... Nature cell biology 17 (6), 715-725, 2015 | 92 | 2015 |
| Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane X Xu, D Wang, C Zheng, B Gao, J Fan, P Cheng, B Liu, L Yang, Z Luo Theranostics 9 (8), 2252, 2019 | 90 | 2019 |
| Chromatin remodeling, DNA damage repair and aging B Liu, R KH Yip, Z Zhou Current genomics 13 (7), 533-547, 2012 | 84 | 2012 |
| MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis KM Chan, HLX Wong, G Jin, B Liu, R Cao, Y Cao, K Lehti, K Tryggvason, ... Developmental cell 22 (6), 1176-1190, 2012 | 82 | 2012 |
| Lamin AC, laminopathies and premature ageing B Liu, Z Zhou Histology and histopathology, 2008 | 82 | 2008 |
| Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer M Tang, X Lu, C Zhang, C Du, L Cao, T Hou, Z Li, B Tu, Z Cao, Y Li, ... Theranostics 7 (5), 1346, 2017 | 72 | 2017 |
| HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration X Tang, G Li, F Su, Y Cai, L Shi, Y Meng, Z Liu, J Sun, M Wang, M Qian, ... Nucleic Acids Research 48 (6), 2912-2923, 2020 | 68 | 2020 |
| A SIRT1-centered circuitry regulates breast cancer stemness and metastasis L Shi, X Tang, M Qian, Z Liu, F Meng, L Fu, Z Wang, WG Zhu, JD Huang, ... Oncogene 37 (49), 6299-6315, 2018 | 68 | 2018 |
| SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease W Li, W Feng, X Su, D Luo, Z Li, Y Zhou, Y Zhu, M Zhang, J Chen, B Liu, ... The Journal of clinical investigation 132 (1), 2022 | 66 | 2022 |
| Vascular endothelium–targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model S Sun, W Qin, X Tang, Y Meng, W Hu, S Zhang, M Qian, Z Liu, X Cao, ... Science advances 6 (8), eaay5556, 2020 | 64 | 2020 |
| Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice F Meng, M Qian, B Peng, L Peng, X Wang, K Zheng, Z Liu, X Tang, ... elife 9, e55828, 2020 | 63 | 2020 |
Zhongjun ZhouThe University of Hong Kong, Faculty of MedicineVerified email at hku.hk
