Onur Dagliyan
Onur Dagliyan
Research Fellow, Harvard Medical School
כתובת אימייל מאומתת בדומיין hms.harvard.edu
כותרת
צוטט על ידי
צוטט על ידי
שנה
Engineering extrinsic disorder to control protein activity in living cells
O Dagliyan, M Tarnawski, PH Chu, D Shirvanyants, I Schlichting, ...
Science 354 (6318), 1441-1444, 2016
1402016
Optimization based tumor classification from microarray gene expression data
O Dagliyan, F Uney-Yuksektepe, IH Kavakli, M Turkay
PloS one 6 (2), e14579, 2011
1052011
Structural and dynamic determinants of protein-peptide recognition
O Dagliyan, EA Proctor, KM D'Auria, F Ding, NV Dokholyan
Structure 19 (12), 1837-1845, 2011
932011
Rational design of a ligand-controlled protein conformational switch
O Dagliyan, D Shirvanyants, AV Karginov, F Ding, L Fee, ...
Proceedings of the National Academy of Sciences 110 (17), 6800-6804, 2013
922013
Knowledge-based design of a biosensor to quantify localized ERK activation in living cells
L Kummer, CW Hsu, O Dagliyan, C MacNevin, M Kaufholz, ...
Chemistry & biology 20 (6), 847-856, 2013
532013
Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms
PH Chu, D Tsygankov, ME Berginski, O Dagliyan, SM Gomez, TC Elston, ...
Proceedings of the National Academy of Sciences 111 (34), 12420-12425, 2014
442014
Computational design of chemogenetic and optogenetic split proteins
O Dagliyan, A Krokhotin, I Ozkan-Dagliyan, A Deiters, CJ Der, KM Hahn, ...
Nature communications 9 (1), 1-8, 2018
342018
FRET binding antenna reports spatiotemporal dynamics of GDI–Cdc42 GTPase interactions
L Hodgson, D Spiering, M Sabouri-Ghomi, O Dagliyan, ...
Nature chemical biology 12 (10), 802-809, 2016
342016
Computational approaches to understanding protein aggregation in neurodegeneration
RL Redler, D Shirvanyants, O Dagliyan, F Ding, DN Kim, P Kota, ...
Journal of molecular cell biology 6 (2), 104-115, 2014
282014
Structure based discovery of small molecules to regulate the activity of human insulin degrading enzyme
B Çakir, O Dağliyan, E Dağyildiz, İ Bariş, IH Kavakli, S Kizilel, M Türkay
PLoS One 7 (2), e31787, 2012
272012
Classification of Cytochrome P450 Inhibitors with Respect to Binding Free Energy and pIC50 Using Common Molecular Descriptors
O Dagliyan, IH Kavakli, M Turkay
Journal of chemical information and modeling 49 (10), 2403-2411, 2009
272009
Intrinsic disorder mediates cooperative signal transduction in STIM1
Y Furukawa, S Teraguchi, T Ikegami, O Dagliyan, L Jin, D Hall, ...
Journal of molecular biology 426 (10), 2082-2097, 2014
242014
Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity
TC Freeman Jr, JL Black, HG Bray, O Dagliyan, YI Wu, A Tripathy, ...
Biochemistry 52 (40), 7082-7090, 2013
22*2013
Profiling cellular morphodynamics by spatiotemporal spectrum decomposition
X Ma, O Dagliyan, KM Hahn, G Danuser
PLoS computational biology 14 (8), e1006321, 2018
192018
Engineering proteins for allosteric control by light or ligands
O Dagliyan, NV Dokholyan, KM Hahn
Nature protocols 14 (6), 1863-1883, 2019
162019
Engineering Pak1 allosteric switches
O Dagliyan, AV Karginov, S Yagishita, ME Gale, H Wang, ...
ACS synthetic biology 6 (7), 1257-1262, 2017
162017
Gain-of-Function mutation W493R in the epithelial sodium channel allosterically reconfigures intersubunit coupling
M Shobair, O Dagliyan, P Kota, YL Dang, H He, MJ Stutts, NV Dokholyan
Journal of Biological Chemistry 291 (8), 3682-3692, 2016
112016
Controlling protein conformation with light
O Dagliyan, KM Hahn
Current opinion in structural biology 57, 17-22, 2019
82019
Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
I Ozkan-Dagliyan, JN Diehl, SD George, A Schaefer, B Papke, ...
Cell reports 31 (11), 107764, 2020
72020
Rational design and implementation of a chemically inducible heterotrimerization system
HD Wu, M Kikuchi, O Dagliyan, AK Aragaki, H Nakamura, NV Dokholyan, ...
Nature Methods 17, 928–936, 2020
42020
המערכת אינה יכולה לבצע את הפעולה כעת. נסה שוב מאוחר יותר.
מאמרים 1–20