Onur Dagliyan
Onur Dagliyan
Research Fellow, Harvard Medical School
Verified email at - Homepage
Cited by
Cited by
Engineering extrinsic disorder to control protein activity in living cells
O Dagliyan, M Tarnawski, PH Chu, D Shirvanyants, I Schlichting, ...
Science 354 (6318), 1441-1444, 2016
Rational design of a ligand-controlled protein conformational switch
O Dagliyan, D Shirvanyants, A Karginov, F Ding, SN Chandrasekaran, ...
Proceedings of the National Academy of Sciences (PNAS) 104 (2), 18a-19a, 2013
Optimization based tumor classification from microarray gene expression data
O Dagliyan, F Uney-Yuksektepe, IH Kavakli, M Turkay
PloS one 6 (2), e14579, 2011
Structural and dynamic determinants of protein-peptide recognition
O Dagliyan, EA Proctor, KM D'Auria, F Ding, NV Dokholyan
Structure 19 (12), 1837-1845, 2011
Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network
EL Yap, NL Pettit, CP Davis, MA Nagy, DA Harmin, E Golden, O Dagliyan, ...
Nature 590 (7844), 115-121, 2021
Computational design of chemogenetic and optogenetic split proteins
O Dagliyan, A Krokhotin, I Ozkan-Dagliyan, A Deiters, CJ Der, KM Hahn, ...
Nature communications 9 (1), 4042, 2018
Low-dose vertical inhibition of the RAF-MEK-ERK cascade causes apoptotic death of KRAS mutant cancers
I Ozkan-Dagliyan, JN Diehl, SD George, A Schaefer, B Papke, ...
Cell reports 31 (11), 2020
Knowledge-based design of a biosensor to quantify localized ERK activation in living cells
L Kummer, CW Hsu, O Dagliyan, C MacNevin, M Kaufholz, ...
Chemistry & biology 20 (6), 847-856, 2013
Expression of the transcription factor PU. 1 induces the generation of microglia-like cells in human cortical organoids
B Cakir, Y Tanaka, FR Kiral, Y Xiang, O Dagliyan, J Wang, M Lee, ...
Nature Communications 13 (1), 430, 2022
Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms
PH Chu, D Tsygankov, ME Berginski, O Dagliyan, SM Gomez, TC Elston, ...
Proceedings of the National Academy of Sciences 111 (34), 12420-12425, 2014
Engineering proteins for allosteric control by light or ligands
O Dagliyan, NV Dokholyan, KM Hahn
Nature protocols 14 (6), 1863-1883, 2019
FRET binding antenna reports spatiotemporal dynamics of GDI–Cdc42 GTPase interactions
L Hodgson, D Spiering, M Sabouri-Ghomi, O Dagliyan, ...
Nature chemical biology 12 (10), 802-809, 2016
Computational approaches to understanding protein aggregation in neurodegeneration
RL Redler, D Shirvanyants, O Dagliyan, F Ding, DN Kim, P Kota, ...
Journal of molecular cell biology 6 (2), 104-115, 2014
Profiling cellular morphodynamics by spatiotemporal spectrum decomposition
X Ma, O Dagliyan, KM Hahn, G Danuser
PLoS computational biology 14 (8), e1006321, 2018
Structure based discovery of small molecules to regulate the activity of human insulin degrading enzyme
B Cakir, O Dağliyan, E Dağyildiz, İ Bariş, IH Kavakli, S Kizilel, M Türkay
PLoS One 7 (2), e31787, 2012
Rational design and implementation of a chemically inducible heterotrimerization system
HD Wu, M Kikuchi, O Dagliyan, AK Aragaki, H Nakamura, NV Dokholyan, ...
Nature Methods 17, 928–936, 2020
Rational design and implementation of a chemically inducible hetero-trimerization system
HD Wu, M Kikuchi, O Dagliyan, AK Aragaki, H Nakamura, NV Dokholyan, ...
bioRxiv, 2020
Intrinsic disorder mediates cooperative signal transduction in STIM1
Y Furukawa, S Teraguchi, T Ikegami, O Dagliyan, L Jin, D Hall, ...
Journal of molecular biology 426 (10), 2082-2097, 2014
Classification of Cytochrome P450 Inhibitors with Respect to Binding Free Energy and pIC50 Using Common Molecular Descriptors
O Dagliyan, IH Kavakli, M Turkay
Journal of chemical information and modeling 49 (10), 2403-2411, 2009
Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity
TC Freeman Jr, JL Black, HG Bray, O Dagliyan, YI Wu, A Tripathy, ...
Biochemistry 52 (40), 7082-7090, 2013
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