עקוב אחר
Vincent Setola
Vincent Setola
West Virginia University School of Medicine
כתובת אימייל מאומתת בדומיין hsc.wvu.edu
כותרת
צוטט על ידי
צוטט על ידי
שנה
Predicting new molecular targets for known drugs
MJ Keiser, V Setola, JJ Irwin, C Laggner, AI Abbas, SJ Hufeisen, ...
Nature 462 (7270), 175-181, 2009
18372009
Automated design of ligands to polypharmacological profiles
J Besnard, GF Ruda, V Setola, K Abecassis, RM Rodriguiz, XP Huang, ...
Nature 492 (7428), 215-220, 2012
8412012
Discovery of a novel member of the histamine receptor family
T Nguyen, DA Shapiro, SR George, V Setola, DK Lee, R Cheng, L Rauser, ...
Molecular pharmacology 59 (3), 427-433, 2001
4932001
Discovery of β-arrestin–biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy
JA Allen, JM Yost, V Setola, X Chen, MF Sassano, M Chen, S Peterson, ...
Proceedings of the National Academy of Sciences 108 (45), 18488-18493, 2011
3802011
3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro
V Setola, SJ Hufeisen, KJ Grande-Allen, I Vesely, RA Glennon, B Blough, ...
Molecular pharmacology 63 (6), 1223-1229, 2003
3652003
Ligand discovery from a dopamine D3 receptor homology model and crystal structure
J Carlsson, RG Coleman, V Setola, JJ Irwin, H Fan, A Schlessinger, A Sali, ...
Nature chemical biology 7 (11), 769-778, 2011
3512011
Serotonin receptors and heart valve disease—it was meant 2B
JD Hutcheson, V Setola, BL Roth, WD Merryman
Pharmacology & therapeutics 132 (2), 146-157, 2011
2542011
Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil
D Zolkowska, R Jain, RB Rothman, JS Partilla, BL Roth, V Setola, ...
Journal of Pharmacology and Experimental Therapeutics 329 (2), 738-746, 2009
2102009
Identifying mechanism-of-action targets for drugs and probes
E Gregori-Puigjané, V Setola, J Hert, BA Crews, JJ Irwin, E Lounkine, ...
Proceedings of the National Academy of Sciences 109 (28), 11178-11183, 2012
2052012
Neurochemical profiles of some novel psychoactive substances
L Iversen, S Gibbons, R Treble, V Setola, XP Huang, BL Roth
European journal of pharmacology 700 (1-3), 147-151, 2013
1882013
The ketamine analogue methoxetamine and 3-and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor
BL Roth, S Gibbons, W Arunotayanun, XP Huang, V Setola, R Treble, ...
PloS one 8 (3), e59334, 2013
1742013
Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy
F Jaffré, P Bonnin, J Callebert, H Debbabi, V Setola, S Doly, L Monassier, ...
Circulation research 104 (1), 113-123, 2009
1682009
Serotonin 5-HT2B receptors are required for 3, 4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro
S Doly, E Valjent, V Setola, J Callebert, D Hervé, JM Launay, L Maroteaux
Journal of Neuroscience 28 (11), 2933-2940, 2008
1562008
Chemical informatics and target identification in a zebrafish phenotypic screen
C Laggner, D Kokel, V Setola, A Tolia, H Lin, JJ Irwin, MJ Keiser, ...
Nature chemical biology 8 (2), 144-146, 2012
1462012
Structure–Functional Selectivity Relationship Studies of β-Arrestin-Biased Dopamine D2 Receptor Agonists
X Chen, MF Sassano, L Zheng, V Setola, M Chen, X Bai, SV Frye, ...
Journal of medicinal chemistry 55 (16), 7141-7153, 2012
1402012
Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine2B receptor agonists: implications for drug safety assessment
XP Huang, V Setola, PN Yadav, JA Allen, SC Rogan, BJ Hanson, ...
Molecular pharmacology 76 (4), 710-722, 2009
1362009
Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice
JPR Jacobsen, WB Siesser, BD Sachs, S Peterson, MJ Cools, V Setola, ...
Molecular psychiatry 17 (7), 694-704, 2012
1352012
Photochemical activation of TRPA1 channels in neurons and animals
D Kokel, CYJ Cheung, R Mills, J Coutinho-Budd, L Huang, V Setola, ...
Nature chemical biology 9 (4), 257-263, 2013
1222013
5-HT2B antagonism arrests non-canonical TGF-β1-induced valvular myofibroblast differentiation
JD Hutcheson, LM Ryzhova, V Setola, WD Merryman
Journal of molecular and cellular cardiology 53 (5), 707-714, 2012
1222012
Design, synthesis, and validation of a β-turn mimetic library targeting protein–protein and peptide–receptor interactions
LR Whitby, Y Ando, V Setola, PK Vogt, BL Roth, DL Boger
Journal of the American Chemical Society 133 (26), 10184-10194, 2011
922011
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מאמרים 1–20