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Edward Koellhoffer
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Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation
BG Wilson, X Wang, X Shen, ES McKenna, ME Lemieux, YJ Cho, ...
Cancer cell 18 (4), 316-328, 2010
6852010
Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters
MY Tolstorukov, CG Sansam, P Lu, EC Koellhoffer, KC Helming, BH Alver, ...
Proceedings of the National Academy of Sciences 110 (25), 10165-10170, 2013
2052013
Old maids: aging and its impact on microglia function
EC Koellhoffer, LD McCullough, RM Ritzel
International journal of molecular sciences 18 (4), 769, 2017
1982017
The effects of estrogen in ischemic stroke
EC Koellhoffer, LD McCullough
Translational stroke research 4, 390-401, 2013
1822013
Ischemic stroke induces gut permeability and enhances bacterial translocation leading to sepsis in aged mice
J Crapser, R Ritzel, R Verma, VR Venna, F Liu, A Chauhan, E Koellhoffer, ...
Aging (Albany NY) 8 (5), 1049, 2016
1492016
The G-quadruplex DNA stabilizing drug pyridostatin promotes DNA damage and downregulates transcription of Brca1 in neurons
JF Moruno-Manchon, EC Koellhoffer, J Gopakumar, S Hambarde, N Kim, ...
Aging (Albany NY) 9 (9), 1957, 2017
882017
Integrating plant molecular farming and materials research for next-generation vaccines
YH Chung, D Church, EC Koellhoffer, E Osota, S Shukla, EP Rybicki, ...
Nature Reviews Materials 7 (5), 372-388, 2022
812022
Multiparity improves outcomes after cerebral ischemia in female mice despite features of increased metabovascular risk
RM Ritzel, AR Patel, M Spychala, R Verma, J Crapser, EC Koellhoffer, ...
Proceedings of the National Academy of Sciences 114 (28), E5673-E5682, 2017
472017
Epigenetic inactivation of the tumor suppressor BIN1 drives proliferation of SNF5-deficient tumors
ES McKenna, P Tamayo, YJ Cho, EJ Tillman, EL Mora-Blanco, ...
Cell Cycle 11 (10), 1956-1965, 2012
352012
Inhibition of calcium/calmodulin‐dependent protein kinase kinase (Ca MKK) exacerbates impairment of endothelial cell and blood–brain barrier after stroke
P Sun, F Bu, JW Min, Y Munshi, MD Howe, L Liu, EC Koellhoffer, L Qi, ...
European Journal of Neuroscience 49 (1), 27-39, 2019
302019
Transforming growth factor-β promotes basement membrane fibrosis, alters perivascular cerebrospinal fluid distribution, and worsens neurological recovery in the aged brain …
MD Howe, JW Furr, Y Munshi, MA Roy-O’Reilly, ME Maniskas, ...
Geroscience 41, 543-559, 2019
262019
Ras-related C3 botulinum toxin substrate 1 promotes axonal regeneration after stroke in mice
L Liu, H Yuan, Y Yi, EC Koellhoffer, Y Munshi, F Bu, Y Zhang, Z Zhang, ...
Translational stroke research 9, 506-514, 2018
242018
Myeloid-specific TAK1 deletion results in reduced brain monocyte infiltration and improved outcomes after stroke
A Chauhan, J Hudobenko, A Al Mamun, EC Koellhoffer, A Patrizz, ...
Journal of neuroinflammation 15, 1-10, 2018
132018
Inactivated cowpea mosaic virus in combination with OX40 agonist primes potent antitumor immunity in a bilateral melanoma mouse model
EC Koellhoffer, C Mao, V Beiss, L Wang, SN Fiering, CE Boone, ...
Molecular pharmaceutics 19 (2), 592-601, 2022
122022
Cowpea mosaic virus and natural killer cell agonism for in situ cancer vaccination
EC Koellhoffer, NF Steinmetz
Nano letters 22 (13), 5348-5356, 2022
102022
Inactivated cowpea mosaic virus for in situ vaccination: differential efficacy of formalin vs UV-inactivated formulations
E Jung, C Mao, M Bhatia, EC Koellhoffer, SN Fiering, NF Steinmetz
Molecular pharmaceutics 20 (1), 500-507, 2022
62022
Abstract WP122: heterochronic parabiosis reverses the epigenetic imbalance of the aged central nervous system
EC Koellhoffer, D Morales-Scheihing, J d’Aigle, LD McCullough
Stroke 48 (suppl_1), AWP122-AWP122, 2017
32017
Tilting the balance of M1/M2 microglial phenotypes: inhibition of Ezh2 leads to decreased M1 and enhanced M2 phenotype
E Koellhoffer, R Ritzel, J Grenier, L McCullough
Journal of Neuroimmunology 275 (1), 157, 2014
32014
Abstract T P80: Inhibition of Ezh2 leads to decreased M1 and enhanced M2 microglia phenotypes
E Koellhoffer, J Grenier, R Ritzel, L McCullough
Stroke 46 (suppl_1), ATP80-ATP80, 2015
22015
Circulating peripheral factors induce age-related epigenetic changes in microglia which induces a primed phenotype
EC Koellhoffer, J d'Aigle, D Morales-Scheihing, LD McCullough
Stroke 50 (Suppl_1), A23-A23, 2019
12019
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