Modeling the functional effects of allosteric modulators at pharmacological receptors: an extension of the two-state model of receptor activation DA Hall Molecular Pharmacology 58, 1412, 2000 | 239 | 2000 |
Receptors for ADP on human blood platelets SMO Hourani, DA Hall Trends in pharmacological sciences 15 (4), 103-108, 1994 | 178 | 1994 |
Evidence that antipsychotic drugs are inverse agonists at D2 dopamine receptors DA Hall, PG Strange British Journal of Pharmacology 121, 731, 1997 | 137 | 1997 |
Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients P Vijayanand, K Durkin, G Hartmann, J Morjaria, G Seumois, KJ Staples, ... The Journal of Immunology 184 (8), 4568-4574, 2010 | 117 | 2010 |
Signalling by CXC‐chemokine receptors 1 and 2 expressed in CHO cells: a comparison of calcium mobilization, inhibition of adenylyl cyclase and stimulation of GTPγS binding … DA Hall, IJM Beresford, C Browning, H Giles British journal of pharmacology 126 (3), 810-818, 1999 | 103 | 1999 |
Safety and efficacy of an oral CCR 3 antagonist in patients with asthma and eosinophilic bronchitis: a randomized, placebo‐controlled clinical trial H Neighbour, LP Boulet, C Lemiere, R Sehmi, R Leigh, AR Sousa, ... Clinical & Experimental Allergy 44 (4), 508-516, 2014 | 102 | 2014 |
Activation of Microtubule‐Associated Protein Kinase (Erk) and p70 S6 Kinase by D2 Dopamine Receptors GI Welsh, DA Hall, A Warnes, PG Strange, CG Proud Journal of neurochemistry 70 (5), 2139-2146, 1998 | 93 | 1998 |
Pharmacological analysis of dopamine stimulation of [35S]‐GTPγS binding via human D2short and D2long dopamine receptors expressed in recombinant cells B Gardner, DA Hall, PG Strange British journal of pharmacology 118 (6), 1544-1550, 1996 | 88 | 1996 |
CCR4 in human allergen‐induced late responses in the skin and lung KT Nouri‐Aria, D Wilson, JN Francis, LA Jopling, MR Jacobson, ... European journal of immunology 32 (7), 1933-1938, 2002 | 80 | 2002 |
Effects of the P2-purinoceptor antagonist, suramin, on human platelet aggregation induced by adenosine 5'-diphosphate. SM Hourani, H DA, N CJ British Journal of Pharmacology 105, 453, 1992 | 72 | 1992 |
Effects of analogues of adenine nucleotides on increases in intracellular calcium mediated by P2T-purinoceptors on human blood platelets DA Hall, SM Hourani British Journal of Pharmacology 108, 728, 1993 | 71 | 1993 |
Distinct conformations of the chemokine receptor CCR4 with implications for its targeting in allergy JM Viney, DP Andrew, RM Phillips, A Meiser, P Patel, M Lennartz-Walker, ... The Journal of Immunology 192 (7), 3419-3427, 2014 | 55 | 2014 |
Antagonism of angiotensin 1–7 prevents the therapeutic effects of recombinant human ACE2 VB Patel, A Takawale, T Ramprasath, SK Das, R Basu, MB Grant, DA Hall, ... Journal of molecular medicine 93, 1003-1013, 2015 | 54 | 2015 |
Internalization of the chemokine receptor CCR4 can be evoked by orthosteric and allosteric receptor antagonists L Ajram, M Begg, R Slack, J Cryan, D Hall, S Hodgson, A Ford, A Barnes, ... European journal of pharmacology 729, 75-85, 2014 | 53 | 2014 |
Pharmacological characterization of GSK1004723, a novel, long‐acting antagonist at histamine H1 and H3 receptors RJ Slack, LJ Russell, DA Hall, MA Luttmann, AJ Ford, KA Saunders, ... British journal of pharmacology 164 (6), 1627-1641, 2011 | 49 | 2011 |
Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a … A Cahn, S Hodgson, R Wilson, J Robertson, J Watson, M Beerahee, ... BMC Pharmacology and Toxicology 14, 1-11, 2013 | 46 | 2013 |
Agonist Action at D2(short) Dopamine Receptors Determined in Ligand Binding and Functional Assays BR Gardner, DA Hall, PG Strange Journal of neurochemistry 69 (6), 2589-2598, 1997 | 45 | 1997 |
Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data LA Stott, DA Hall, ND Holliday Biochemical pharmacology 101, 1-12, 2016 | 44 | 2016 |
Development of operational models of receptor activation including constitutive receptor activity and their use to determine the efficacy of the chemokine CCL17 at the CC … RJ Slack, DA Hall British Journal of Pharmacology 166 (6), 1774, 2012 | 43 | 2012 |
P2T purinoceptors: ADP receptors on platelets SMO Hourani, DA Hall Ciba Foundation Symposium 198‐P2 Purinoceptors: Localization, Function and …, 2007 | 43 | 2007 |