| Non‐viral CRISPR/Cas gene editing in vitro and in vivo enabled by synthetic nanoparticle co‐delivery of Cas9 mRNA and sgRNA JB Miller, S Zhang, P Kos, H Xiong, K Zhou, SS Perelman, H Zhu, ... Angewandte Chemie 129 (4), 1079-1083, 2017 | 590 | 2017 |
| Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model K Zhou, LH Nguyen, JB Miller, Y Yan, P Kos, H Xiong, L Li, J Hao, ... Proceedings of the National Academy of Sciences 113 (3), 520-525, 2016 | 169 | 2016 |
| Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes U Lächelt, P Kos, FM Mickler, A Herrmann, EE Salcher, W Rödl, ... Nanomedicine: Nanotechnology, Biology and Medicine 10 (1), 35-44, 2014 | 161 | 2014 |
| Stabilizing effect of tyrosine trimers on pDNA and siRNA polyplexes C Troiber, D Edinger, P Kos, L Schreiner, R Kläger, A Herrmann, ... Biomaterials 34 (5), 1624-1633, 2013 | 128 | 2013 |
| Rapid synthesis of a lipocationic polyester library via ring-opening polymerization of functional valerolactones for efficacious siRNA delivery J Hao, P Kos, K Zhou, JB Miller, L Xue, Y Yan, H Xiong, S Elkassih, ... Journal of the American Chemical Society 137 (29), 9206-9209, 2015 | 104 | 2015 |
| Solid-phase-assisted synthesis of targeting peptide–PEG–oligo (ethane amino) amides for receptor-mediated gene delivery I Martin, C Dohmen, C Mas-Moruno, C Troiber, P Kos, D Schaffert, ... Organic & biomolecular chemistry 10 (16), 3258-3268, 2012 | 100 | 2012 |
| Sequence-defined four-arm oligo (ethanamino) amides for pDNA and siRNA delivery: Impact of building blocks on efficacy EE Salcher, P Kos, T Fröhlich, N Badgujar, M Scheible, E Wagner Journal of controlled release 164 (3), 380-386, 2012 | 94 | 2012 |
| Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer P Kos, U Lächelt, A Herrmann, FM Mickler, M Döblinger, D He, ... Nanoscale 7 (12), 5350-5362, 2015 | 86 | 2015 |
| Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells Y Yan, L Liu, H Xiong, JB Miller, K Zhou, P Kos, KE Huffman, S Elkassih, ... Proceedings of the National Academy of Sciences 113 (39), E5702-E5710, 2016 | 82 | 2016 |
| PEI fluorination reduces toxicity and promotes liver-targeted siRNA delivery L Xue, Y Yan, P Kos, X Chen, DJ Siegwart Drug Delivery and Translational Research 11, 255-260, 2021 | 68 | 2021 |
| Activatable water-soluble probes enhance tumor imaging by responding to dysregulated pH and exhibiting high tumor-to-liver fluorescence emission contrast H Xiong, P Kos, Y Yan, K Zhou, JB Miller, S Elkassih, DJ Siegwart Bioconjugate chemistry 27 (7), 1737-1744, 2016 | 61 | 2016 |
| Combinatorial optimization of sequence-defined oligo (ethanamino) amides for folate receptor-targeted pDNA and siRNA delivery D He, K Müller, A Krhac Levacic, P Kos, U Lächelt, E Wagner Bioconjugate chemistry 27 (3), 647-659, 2016 | 61 | 2016 |
| Doxazosin–carrageenan interactions: A novel approach for studying drug–polymer interactions and relation to controlled drug release M Pavli, S Baumgartner, P Kos, K Kogej International journal of pharmaceutics 421 (1), 110-119, 2011 | 61 | 2011 |
| Degradable redox-responsive disulfide-based nanogel drug carriers via dithiol oxidation polymerization SA Elkassih, P Kos, H Xiong, DJ Siegwart Biomaterials science 7 (2), 607-617, 2019 | 55 | 2019 |
| Comb-like oligoaminoethane carriers: change in topology improves pDNA delivery C Scholz, P Kos, E Wagner Bioconjugate chemistry 25 (2), 251-261, 2014 | 51 | 2014 |
| Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes PM Klein, K Müller, C Gutmann, P Kos, AK Levacic, D Edinger, M Höhn, ... Journal of Controlled Release 205, 109-119, 2015 | 48 | 2015 |
| Dual-targeted polyplexes based on sequence-defined peptide-PEG-oligoamino amides P Kos, U Lächelt, D He, Y Nie, Z Gu, E Wagner Journal of pharmaceutical sciences 104 (2), 464-475, 2015 | 48 | 2015 |
| Development of cationic quaternary ammonium sulfonamide amino lipids for nucleic acid delivery JB Miller, P Kos, V Tieu, K Zhou, DJ Siegwart ACS applied materials & interfaces 10 (3), 2302-2311, 2018 | 44 | 2018 |
| Correlation of length of linear oligo (ethanamino) amides with gene transfer and cytotoxicity C Scholz, P Kos, L Leclercq, X Jin, H Cottet, E Wagner ChemMedChem 9 (9), 2104-2110, 2014 | 44 | 2014 |
| Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly (I: C) nanoplexes U Lächelt, V Wittmann, K Müller, D Edinger, P Kos, M Höhn, ... Molecular pharmaceutics 11 (8), 2631-2639, 2014 | 42 | 2014 |
Ernst WagnerProfessor, Ludwig-Maximilians-Universität (LMU) Münchenכתובת אימייל מאומתת בדומיין cup.uni-muenchen.de
