| OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis TET Mevissen, MK Hospenthal, PP Geurink, PR Elliott, M Akutsu, ... Cell 154 (1), 169-184, 2013 | 576 | 2013 |
| Chemical synthesis of ubiquitin, ubiquitin‐based probes, and diubiquitin F El Oualid, R Merkx, R Ekkebus, DS Hameed, JJ Smit, A de Jong, ... Angewandte Chemie 122 (52), 10347-10351, 2010 | 326 | 2010 |
| Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design W Rut, Z Lv, M Zmudzinski, S Patchett, D Nayak, SJ Snipas, F El Oualid, ... Science advances 6 (42), eabd4596, 2020 | 324 | 2020 |
| The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types AC Faesen, MPA Luna-Vargas, PP Geurink, M Clerici, R Merkx, ... Chemistry & biology 18 (12), 1550-1561, 2011 | 223 | 2011 |
| From disulfide-to thioether-linked glycoproteins GJ Bernardes, EJ Grayson, S Thompson, JM Chalker, JC Errey, ... ChemInform 39 (29), i, 2008 | 194 | 2008 |
| An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains JDF Licchesi, J Mieszczanek, TET Mevissen, TJ Rutherford, M Akutsu, ... Nature structural & molecular biology 19 (1), 62-71, 2012 | 155 | 2012 |
| Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne TET Mevissen, Y Kulathu, MPC Mulder, PP Geurink, SL Maslen, M Gersch, ... Nature 538 (7625), 402-405, 2016 | 147 | 2016 |
| A cascading activity-based probe sequentially targets E1–E2–E3 ubiquitin enzymes MPC Mulder, K Witting, I Berlin, JN Pruneda, KP Wu, JG Chang, R Merkx, ... Nature chemical biology 12 (7), 523-530, 2016 | 142 | 2016 |
| Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G DD Sahtoe, WJ van Dijk, F El Oualid, R Ekkebus, H Ovaa, TK Sixma Molecular cell 57 (5), 887-900, 2015 | 116 | 2015 |
| Activity profiling and structures of inhibitor-bound SARS-CoV-2-PLpro protease provides a framework for anti-COVID-19 drug design W Rut, Z Lv, M Zmudzinski, S Patchett, D Nayak, SJ Snipas, F El Oualid, ... biorxiv, 2020.04. 29.068890, 2020 | 113 | 2020 |
| A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents PP Geurink, A Jonker, DS Hameed, H Ovaa ChemBioChem 13 (2), 293, 2012 | 101 | 2012 |
| A native chemical ligation handle that enables the synthesis of advanced activity‐based probes: diubiquitin as a case study MPC Mulder, F El Oualid, J ter Beek, H Ovaa ChemBioChem 15 (7), 946-949, 2014 | 91 | 2014 |
| Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes DS Hewings, J Heideker, TP Ma, AP AhYoung, F El Oualid, A Amore, ... Nature Communications 9 (1), 1162, 2018 | 88 | 2018 |
| Naturally occurring isothiocyanates exert anticancer effects by inhibiting deubiquitinating enzymes AP Lawson, MJC Long, RT Coffey, Y Qian, E Weerapana, F El Oualid, ... Cancer research 75 (23), 5130-5142, 2015 | 79 | 2015 |
| Nonhydrolyzable Ubiquitin− Isopeptide Isosteres as Deubiquitinating Enzyme Probes. A Shanmugham, A Fish, MPA Luna-Vargas, AC Faesen, FE Oualid, ... Journal of the American Chemical Society 132 (26), 8834-8835, 2010 | 78 | 2010 |
| Atomic-scale detection of organic molecules coupled to single-walled carbon nanotubes SY Hong, G Tobias, B Ballesteros, F El Oualid, JC Errey, KJ Doores, ... Journal of the American Chemical Society 129 (36), 10966-10967, 2007 | 77 | 2007 |
| Molecular characterization of ubiquitin‐specific protease 18 reveals substrate specificity for interferon‐stimulated gene 15 A Basters, PP Geurink, F El Oualid, L Ketscher, MS Casutt, E Krause, ... The FEBS journal 281 (7), 1918-1928, 2014 | 62 | 2014 |
| Metabolic control of BRISC–SHMT2 assembly regulates immune signalling M Walden, L Tian, RL Ross, UM Sykora, DP Byrne, EL Hesketh, ... Nature 570 (7760), 194-199, 2019 | 60 | 2019 |
| A practical synthesis of gramicidin S and sugar amino acid containing analogues GM Grotenbreg, M Kronemeijer, MSM Timmer, F El Oualid, RM van Well, ... The Journal of Organic Chemistry 69 (23), 7851-7859, 2004 | 60 | 2004 |
| Alkylated sugar amino acids: a new entry toward highly functionalized dipeptide isosters M Raunkjær, F El Oualid, GA van der Marel, HS Overkleeft, M Overhand Organic Letters 6 (18), 3167-3170, 2004 | 54 | 2004 |
