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Programmable RNA recognition and cleavage by CRISPR/Cas9 MR O’Connell, BL Oakes, SH Sternberg, A East-Seletsky, M Kaplan, ... Nature 516 (7530), 263-266, 2014 | 779 | 2014 |
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer HW Cheung, GS Cowley, BA Weir, JS Boehm, S Rusin, JA Scott, A East, ... Proceedings of the National Academy of Sciences 108 (30), 12372-12377, 2011 | 520 | 2011 |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies GS Cowley, BA Weir, F Vazquez, P Tamayo, JA Scott, S Rusin, ... Scientific data 1 (1), 1-12, 2014 | 483 | 2014 |
RNA targeting by functionally orthogonal type VI-A CRISPR-Cas enzymes A East-Seletsky, MR O’Connell, D Burstein, GJ Knott, JA Doudna Molecular cell 66 (3), 373-383. e3, 2017 | 311 | 2017 |
ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing X Chen, Y Shen, W Draper, JD Buenrostro, U Litzenburger, SW Cho, ... Nature methods 13 (12), 1013-1020, 2016 | 256 | 2016 |
Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme GJ Knott, A East-Seletsky, JC Cofsky, JM Holton, E Charles, ... Nature structural & molecular biology 24 (10), 825-833, 2017 | 164 | 2017 |
RNA binding and HEPN-nuclease activation are decoupled in CRISPR-Cas13a A Tambe, A East-Seletsky, GJ Knott, JA Doudna, MR O’Connell Cell Reports 24 (4), 1025-1036, 2018 | 135 | 2018 |
Identification of a Minimal Peptide Tag for in Vivo and in Vitro Loading of Encapsulin C Cassidy-Amstutz, L Oltrogge, CC Going, A Lee, P Teng, D Quintanilla, ... Biochemistry 55 (24), 3461-3468, 2016 | 120 | 2016 |
Methods and compositions for detecting a target RNA JA Doudna, MR O'connell, A East-Seletsky, SC Knight, JHD Cate US Patent 10,337,051, 2019 | 57 | 2019 |
Methods and compositions for detecting a target RNA JA Doudna, MR O'connell, A East-Seletsky, SC Knight, JHD Cate US Patent 10,494,664, 2019 | 46 | 2019 |
Methods and compositions for detecting a target RNA JA Doudna, MR O'connell, A East-Seletsky, SC Knight, JHD Cate US Patent 11,459,600, 2022 | 26 | 2022 |
Methods and compositions for detecting a target RNA JA Doudna, A East-Seletsky, SC Knight, JHD Cate US Patent 11,840,725, 2023 | 12 | 2023 |
Erratum: Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies GS Cowley, BA Weir, F Vazquez, P Tamayo, JA Scott, S Rusin, ... Scientific data 1 (1), 140044, 2014 | 4 | 2014 |
Methods and compositions for detecting a target RNA JA Doudna, MR O'connell, A East-Seletsky, SC Knight, JHD Cate US Patent 11,827,919, 2023 | 1 | 2023 |
Methods and compositions for detecting a target RNA JA Doudna, MR O'connell, A East-Seletsky, SC Knight, JHD Cate US Patent 11,459,599, 2022 | 1 | 2022 |
Methods and compositions for detecting a target rna JA Doudna, MR O'connell, A East-Seletsky, SC Knight, JHD Cate US Patent App. 18/492,550, 2024 | | 2024 |
Menetelmiä ja koostumuksia kohde-rna: n detektoimiseksi J Doudna, M O'connell, A East-Seletsky, S Knight, CJ Doudna | | 2022 |
Fremgangsmåder og sammensætninger til detektering af en mål-RNA JA Doudna, A East-Seletsky, SC Knight, CJH Doudna, MR O'connell | | 2022 |