| Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis M Nagahashi, S Ramachandran, EY Kim, JC Allegood, OM Rashid, ... Cancer research 72 (3), 726-735, 2012 | 350 | 2012 |
| Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2 K Takabe, RH Kim, JC Allegood, P Mitra, S Ramachandran, M Nagahashi, ... Journal of Biological Chemistry 285 (14), 10477-10486, 2010 | 307 | 2010 |
| Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network M Nagahashi, EY Kim, A Yamada, S Ramachandran, JC Allegood, ... The FASEB Journal 27 (3), 1001, 2013 | 173 | 2013 |
| TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids A Muir, S Ramachandran, FM Roelants, G Timmons, J Thorner Elife 3, e03779, 2014 | 166 | 2014 |
| Voltage-gated sodium channel modulation by σ-receptors in cardiac myocytes and heterologous systems M Johannessen, S Ramachandran, L Riemer, A Ramos-Serrano, ... American Journal of Physiology-Cell Physiology 296 (5), C1049-C1057, 2009 | 121 | 2009 |
| Is tail vein injection a relevant breast cancer lung metastasis model? OM Rashid, M Nagahashi, S Ramachandran, CI Dumur, JC Schaum, ... Journal of thoracic disease 5 (4), 385, 2013 | 119 | 2013 |
| Resection of the primary tumor improves survival in metastatic breast cancer by reducing overall tumor burden OM Rashid, M Nagahashi, S Ramachandran, L Graham, A Yamada, ... Surgery 153 (6), 771-778, 2013 | 110 | 2013 |
| Identification of regions of the σ-1 receptor ligand binding site using a novel photoprobe A Pal, AR Hajipour, D Fontanilla, S Ramachandran, UB Chu, T Mavlyutov, ... Molecular pharmacology 72 (4), 921-933, 2007 | 104 | 2007 |
| The sigma1 receptor interacts with N-alkyl amines and endogenous sphingolipids S Ramachandran, UB Chu, TA Mavlyutov, A Pal, S Pyne, AE Ruoho European journal of pharmacology 609 (1-3), 19-26, 2009 | 95 | 2009 |
| Lymphangiogenesis: a new player in cancer progression M Nagahashi, S Ramachandran, OM Rashid, K Takabe World journal of gastroenterology: WJG 16 (32), 4003, 2010 | 87 | 2010 |
| Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases MS Donoviel, NC Hait, S Ramachandran, M Maceyka, K Takabe, ... The FASEB Journal 29 (12), 5018, 2015 | 82 | 2015 |
| Juxtaposition of the steroid binding domain-like I and II regions constitutes a ligand binding site in the σ-1 receptor A Pal, UB Chu, S Ramachandran, D Grawoig, LW Guo, AR Hajipour, ... Journal of biological chemistry 283 (28), 19646-19656, 2008 | 65 | 2008 |
| An improved syngeneic orthotopic murine model of human breast cancer progression OM Rashid, M Nagahashi, S Ramachandran, C Dumur, J Schaum, ... Breast cancer research and treatment 147, 501-512, 2014 | 63 | 2014 |
| Purification and characterization of the guinea pig sigma-1 receptor functionally expressed in Escherichia coli S Ramachandran, H Lu, U Prabhu, AE Ruoho Protein expression and purification 51 (2), 283-292, 2007 | 61 | 2007 |
| Sphingolipid biosynthesis upregulation by TOR complex 2–Ypk1 signaling during yeast adaptive response to acetic acid stress JF Guerreiro, A Muir, S Ramachandran, J Thorner, I Sá-Correia Biochemical Journal 473 (23), 4311-4325, 2016 | 53 | 2016 |
| Bevacizumab and breast cancer: what does the future hold? CE Stevenson, M Nagahashi, S Ramachandran, A Yamada, HD Bear, ... Future oncology 8 (4), 403-414, 2012 | 47 | 2012 |
| Photoaffinity Labeling of the Sigma-1 Receptor with N-[3-(4-Nitrophenyl)propyl]-N-dodecylamine: Evidence of Receptor Dimers UB Chu, S Ramachandran, AR Hajipour, AE Ruoho Biochemistry 52 (5), 859-868, 2013 | 45 | 2013 |
| Protein kinase Gin4 negatively regulates flippase function and controls plasma membrane asymmetry FM Roelants, BM Su, J von Wulffen, S Ramachandran, E Sartorel, ... Journal of Cell Biology 208 (3), 299-311, 2015 | 39 | 2015 |
| The ligand binding region of the sigma-1 receptor: studies utilizing photoaffinity probes, sphingosine and N-alkylamines A E Ruoho, U B Chu, S Ramachandran, D Fontanilla, T Mavlyutov, ... Current pharmaceutical design 18 (7), 920-929, 2012 | 38 | 2012 |
| Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription S Ramachandran, D Shida, M Nagahashi, X Fang, S Milstien, K Takabe, ... FEBS letters 584 (18), 4077-4082, 2010 | 35 | 2010 |
