Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition AV Colombo, RK Sadler, G Llovera, V Singh, S Roth, S Heindl, ... Elife 10, e59826, 2021 | 173 | 2021 |
BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology F Peters, H Salihoglu, E Rodrigues, E Herzog, T Blume, S Filser, ... Acta Neuropathologica 135, 695-710, 2018 | 87 | 2018 |
Seeding and transgenic overexpression of alpha‐synuclein triggers dendritic spine pathology in the neocortex S Blumenstock, EF Rodrigues, F Peters, L Blazquez‐Llorca, F Schmidt, ... EMBO molecular medicine 9 (5), 716-731, 2017 | 79 | 2017 |
Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer’s disease C Zou, E Montagna, Y Shi, F Peters, L Blazquez-Llorca, S Shi, S Filser, ... Acta Neuropathologica 129, 909-920, 2015 | 58 | 2015 |
Consequences of pharmacological BACE inhibition on synaptic structure and function K Zhu, F Peters, S Filser, J Herms Biological psychiatry 84 (7), 478-487, 2018 | 57 | 2018 |
Longitudinal PET monitoring of amyloidosis and microglial activation in a second-generation amyloid-β mouse model C Sacher, T Blume, L Beyer, F Peters, F Eckenweber, C Sgobio, ... Journal of Nuclear Medicine 60 (12), 1787-1793, 2019 | 50 | 2019 |
Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study T Blume, C Focke, F Peters, M Deussing, NL Albert, S Lindner, ... Journal of neuroinflammation 15, 1-11, 2018 | 48 | 2018 |
Early and longitudinal microglial activation but not amyloid accumulation predicts cognitive outcome in PS2APP mice C Focke, T Blume, B Zott, Y Shi, M Deussing, F Peters, C Schmidt, ... Journal of Nuclear Medicine 60 (4), 548-554, 2019 | 43 | 2019 |
In vivo imaging reveals reduced activity of neuronal circuits in a mouse tauopathy model P Marinković, S Blumenstock, PM Goltstein, V Korzhova, F Peters, ... Brain 142 (4), 1051-1062, 2019 | 41 | 2019 |
Time courses of cortical glucose metabolism and microglial activity across the life span of wild-type mice: a PET study M Brendel, C Focke, T Blume, F Peters, M Deussing, F Probst, A Jaworska, ... Journal of Nuclear Medicine 58 (12), 1984-1990, 2017 | 41 | 2017 |
Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau M Brendel, M Deussing, T Blume, L Kaiser, F Probst, F Overhoff, F Peters, ... Alzheimer's research & therapy 11, 1-11, 2019 | 25 | 2019 |
Tau deletion reduces plaque‐associated BACE 1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease F Peters, H Salihoglu, K Pratsch, E Herzog, M Pigoni, C Sgobio, ... The EMBO journal 38 (23), e102345, 2019 | 23 | 2019 |
Development of a ligand for in vivo imaging of mutant huntingtin in Huntington’s disease D Bertoglio, J Bard, M Hessmann, L Liu, A Gärtner, S De Lombaerde, ... Science translational medicine 14 (630), eabm3682, 2022 | 19 | 2022 |
Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology M Brendel, BH Yousefi, T Blume, M Herz, C Focke, M Deussing, F Peters, ... Frontiers in Aging Neuroscience 10, 174, 2018 | 19 | 2018 |
The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration M Schoof, M Launspach, D Holdhof, L Nguyen, V Engel, S Filser, F Peters, ... Acta Neuropathologica Communications 7, 1-19, 2019 | 17 | 2019 |
Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy S Blumenstock, MF Angelo, F Peters, MM Dorostkar, VC Ruf, M Luckner, ... Acta neuropathologica 138 (6), 971-986, 2019 | 16 | 2019 |
Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation G Biechele, T Blume, M Deussing, B Zott, Y Shi, X Xiang, N Franzmeier, ... Theranostics 11 (18), 8964, 2021 | 13 | 2021 |
Chronic PPARγ stimulation shifts amyloidosis to higher fibrillarity but improves cognition T Blume, M Deussing, G Biechele, F Peters, B Zott, C Schmidt, ... Frontiers in aging neuroscience 14, 854031, 2022 | 7 | 2022 |
Benefits of global mutant huntingtin lowering diminish over time in a Huntington’s disease mouse model DM Marchionini, JP Liu, A Ambesi-Impiombato, K Kerker, K Cirillo, ... JCI insight 7 (20), 2022 | 5 | 2022 |
Microbiota-derived short chain fatty acids promote Aβ plaque deposition AV Colombo, RK Sadler, G Llovera, V Singh, S Roth, S Heindl, ... BioRxiv, 2020.06. 09.141879, 2020 | 4 | 2020 |