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Amir Schajnovitz
Amir Schajnovitz
Verified email at harvard.edu
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Year
Distinct bone marrow blood vessels differentially regulate haematopoiesis
T Itkin, S Gur-Cohen, JA Spencer, A Schajnovitz, SK Ramasamy, ...
Nature 532 (7599), 323-328, 2016
7332016
Inhibition of dihydroorotate dehydrogenase overcomes differentiation blockade in acute myeloid leukemia
DB Sykes, YS Kfoury, FE Mercier, MJ Wawer, JM Law, MK Haynes, ...
Cell 167 (1), 171-186. e15, 2016
4742016
Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells
A Dar, A Schajnovitz, K Lapid, A Kalinkovich, T Itkin, A Ludin, WM Kao, ...
Leukemia 25 (8), 1286-1296, 2011
2472011
Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin
R Palchaudhuri, B Saez, J Hoggatt, A Schajnovitz, DB Sykes, TA Tate, ...
Nature biotechnology 34 (7), 738-745, 2016
2392016
Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow
A Ludin, T Itkin, S Gur-Cohen, A Mildner, E Shezen, K Golan, O Kollet, ...
Nature immunology 13 (11), 1072-1082, 2012
2332012
S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release
K Golan, Y Vagima, A Ludin, T Itkin, S Cohen-Gur, A Kalinkovich, O Kollet, ...
Blood, The Journal of the American Society of Hematology 119 (11), 2478-2488, 2012
2222012
CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions
A Schajnovitz, T Itkin, G D'uva, A Kalinkovich, K Golan, A Ludin, D Cohen, ...
Nature immunology 12 (5), 391-398, 2011
1972011
Enhanced c-Met activity promotes G-CSF–induced mobilization of hematopoietic progenitor cells via ROS signaling
M Tesio, K Golan, S Corso, S Giordano, A Schajnovitz, Y Vagima, ...
Blood, The Journal of the American Society of Hematology 117 (2), 419-428, 2011
1432011
CD45 regulates retention, motility, and numbers of hematopoietic progenitors, and affects osteoclast remodeling of metaphyseal trabecules
S Shivtiel, O Kollet, K Lapid, A Schajnovitz, P Goichberg, A Kalinkovich, ...
The Journal of experimental medicine 205 (10), 2381-2395, 2008
1312008
Rapid mobilization reveals a highly engraftable hematopoietic stem cell
J Hoggatt, P Singh, TA Tate, BK Chou, SR Datari, S Fukuda, L Liu, ...
Cell 172 (1), 191-204. e10, 2018
1262018
FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation
T Itkin, A Ludin, B Gradus, S Gur-Cohen, A Kalinkovich, A Schajnovitz, ...
Blood, The Journal of the American Society of Hematology 120 (9), 1843-1855, 2012
1262012
Induction of a timed metabolic collapse to overcome cancer chemoresistance
N Van Gastel, JB Spinelli, A Sharda, A Schajnovitz, N Baryawno, C Rhee, ...
Cell Metabolism 32 (3), 391-403. e6, 2020
1222020
Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning
B Saez, F Ferraro, RZ Yusuf, CM Cook, VWC Yu, A Pardo-Saganta, ...
Blood, The Journal of the American Society of Hematology 124 (19), 2937-2947, 2014
522014
The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow
L Shao, J Chang, W Feng, X Wang, EA Williamson, Y Li, A Schajnovitz, ...
Nature communications 9 (1), 2377, 2018
192018
AMD3100 Signals Via the Nervous System, Inducing Release to the Circulation of Bone Marrow SDF-1, Which Is Crucial for Progenitor Cell Mobilization.
A Dar, A Kalinkovich, N Netzer, R Margalit, A Schajnovitz, F Baleux, ...
Blood, The Journal of the American Society of Hematology 108 (11), 1315-1315, 2006
112006
Correction: Corrigendum: Distinct bone marrow blood vessels differentially regulate haematopoiesis
T Itkin, S Gur-Cohen, JA Spencer, A Schajnovitz, SK Ramasamy, ...
Nature 538 (7624), 274-274, 2016
102016
GqPCR-stimulated dephosphorylation of AKT is induced by an IGBP1-mediated PP2A switch
G Nadel, Z Yao, E Wainstein, I Cohen, I Ben-Ami, A Schajnovitz, ...
Cell communication and signaling 20 (1), 5, 2022
92022
Bone's dark side: mutated osteoblasts implicated in leukemia
A Schajnovitz, DT Scadden
Cell Research 24 (4), 383-384, 2014
82014
The chemotactic lipid S1P regulates hematopoietic progenitor cell egress and mobilization via its major receptor S1P1 and by SDF-1 inhibition in a p38/Akt/mTOR dependent manner
K Golan, Y Vagima, A Ludin, T Itkin, A Kalinkovich, S Cohen-Gur, O Kollet, ...
Blood 116 (21), 553, 2010
52010
Untargeted metabolomics identifies glutamine metabolism as a driver of chemoresistance in acute myeloid Leukemia
N van Gastel, A Schajnovitz, C Vidoudez, T Oki, A Sharda, SA Trauger, ...
Blood 130, 2523, 2017
32017
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