| The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized MF Van Delft, AH Wei, KD Mason, CJ Vandenberg, L Chen, PE Czabotar, ... Cancer cell 10 (5), 389-399, 2006 | 1458 | 2006 |
| Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains DL Mallery, CJ Vandenberg, K Hiom The EMBO journal 21 (24), 6755-6762, 2002 | 385 | 2002 |
| DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and Noxa JB Kerr, KJ Hutt, EM Michalak, M Cook, CJ Vandenberg, SH Liew, ... Molecular cell 48 (3), 343-352, 2012 | 261 | 2012 |
| The BRIP1 helicase functions independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair WL Bridge, CJ Vandenberg, RJ Franklin, K Hiom Nature genetics 37 (9), 953-957, 2005 | 236 | 2005 |
| ABT-199, a new Bcl-2–specific BH3 mimetic, has in vivo efficacy against aggressive Myc-driven mouse lymphomas without provoking thrombocytopenia CJ Vandenberg, S Cory Blood, The Journal of the American Society of Hematology 121 (12), 2285-2288, 2013 | 229 | 2013 |
| Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells D Mérino, SL Khaw, SP Glaser, DJ Anderson, LD Belmont, C Wong, ... Blood, The Journal of the American Society of Hematology 119 (24), 5807-5816, 2012 | 224 | 2012 |
| BRCA1-independent ubiquitination of FANCD2 CJ Vandenberg, F Gergely, CY Ong, P Pace, DL Mallery, K Hiom, ... Molecular cell 12 (1), 247-254, 2003 | 180 | 2003 |
| In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas KD Mason, CJ Vandenberg, CL Scott, AH Wei, S Cory, DCS Huang, ... Proceedings of the National Academy of Sciences 105 (46), 17961-17966, 2008 | 175 | 2008 |
| Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells P Sathe, RB Delconte, F Souza-Fonseca-Guimaraes, C Seillet, M Chopin, ... Nature communications 5 (1), 4539, 2014 | 173 | 2014 |
| Apoptosis-promoted tumorigenesis: γ-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death EM Michalak, CJ Vandenberg, ARD Delbridge, L Wu, CL Scott, JM Adams, ... Genes & development 24 (15), 1608-1613, 2010 | 141 | 2010 |
| Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance KJ Campbell, ML Bath, ML Turner, CJ Vandenberg, P Bouillet, D Metcalf, ... Blood, The Journal of the American Society of Hematology 116 (17), 3197-3207, 2010 | 137 | 2010 |
| DNA repair processes are critical mediators of p53-dependent tumor suppression A Janic, LJ Valente, MJ Wakefield, L Di Stefano, L Milla, S Wilcox, H Yang, ... Nature medicine 24 (7), 947-953, 2018 | 130 | 2018 |
| Maximal killing of lymphoma cells by DNA damage–inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim L Happo, MS Cragg, B Phipson, JM Haga, ES Jansen, MJ Herold, ... Blood, The Journal of the American Society of Hematology 116 (24), 5256-5267, 2010 | 118 | 2010 |
| BCL-2 is dispensable for thrombopoiesis and platelet survival MA Debrincat, I Pleines, M Lebois, RM Lane, ML Holmes, J Corbin, ... Cell death & disease 6 (4), e1721-e1721, 2015 | 83 | 2015 |
| Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation AM Jabbour, CP Daunt, BD Green, S Vogel, L Gordon, RS Lee, N Silke, ... Blood, The Journal of the American Society of Hematology 115 (2), 344-352, 2010 | 50 | 2010 |
| Loss of a single Mcl-1 allele inhibits MYC-driven lymphomagenesis by sensitizing pro-B cells to apoptosis S Grabow, ARD Delbridge, BJ Aubrey, CJ Vandenberg, A Strasser Cell reports 14 (10), 2337-2347, 2016 | 49 | 2016 |
| Acquired RAD51C Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma K Nesic, O Kondrashova, RM Hurley, CD McGehee, CJ Vandenberg, ... Cancer research 81 (18), 4709-4722, 2021 | 48 | 2021 |
| Impact of elevated anti-apoptotic MCL-1 and BCL-2 on the development and treatment of MLL-AF9 AML in mice NS Anstee, RA Bilardi, AP Ng, Z Xu, M Robati, CJ Vandenberg, S Cory Cell Death & Differentiation 26 (7), 1316-1331, 2019 | 42 | 2019 |
| Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells CE Teh, JN Gong, D Segal, T Tan, CJ Vandenberg, PL Fedele, MSY Low, ... Cell Death & Differentiation 27 (7), 2217-2233, 2020 | 36 | 2020 |
| Combined loss of PUMA and p21 accelerates c-MYC-driven lymphoma development considerably less than loss of one allele of p53 LJ Valente, S Grabow, CJ Vandenberg, A Strasser, A Janic Oncogene 35 (29), 3866-3871, 2016 | 34 | 2016 |
