Yoshitaka Hiruma
Yoshitaka Hiruma
Verified email at nki.nl
Title
Cited by
Cited by
Year
Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling
Y Hiruma, C Sacristan, ST Pachis, A Adamopoulos, T Kuijt, M Ubbink, ...
Science 348 (6240), 1264-1267, 2015
1892015
Design, synthesis, and evaluation of a lanthanide chelating protein probe: CLaNP-5 yields predictable paramagnetic effects independent of environment
PHJ Keizers, A Saragliadis, Y Hiruma, M Overhand, M Ubbink
Journal of the American Chemical Society 130 (44), 14802-14812, 2008
1732008
The structure of the cytochrome P450cam–putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography
Y Hiruma, MAS Hass, Y Kikui, WM Liu, B Ölmez, SP Skinner, A Blok, ...
Journal of molecular biology 425 (22), 4353-4365, 2013
1062013
A solution model of the complex formed by adrenodoxin and adrenodoxin reductase determined by paramagnetic NMR spectroscopy
PHJ Keizers, B Mersinli, W Reinle, J Donauer, Y Hiruma, F Hannemann, ...
Biochemistry 49 (32), 6846-6855, 2010
602010
Validation of a lanthanide tag for the analysis of protein dynamics by paramagnetic NMR spectroscopy
MAS Hass, PHJ Keizers, A Blok, Y Hiruma, M Ubbink
Journal of the American Chemical Society 132 (29), 9952-9953, 2010
472010
Identification of productive and futile encounters in an electron transfer protein complex
W Andrałojć, Y Hiruma, WM Liu, E Ravera, M Nojiri, G Parigi, C Luchinat, ...
Proceedings of the National Academy of Sciences 114 (10), E1840-E1847, 2017
412017
Delicate conformational balance of the redox enzyme cytochrome P450cam
SP Skinner, WM Liu, Y Hiruma, M Timmer, A Blok, MAS Hass, M Ubbink
Proceedings of the National Academy of Sciences 112 (29), 9022-9027, 2015
342015
Endogenous polyamines reduce the toxicity of soluble Aβ peptide aggregates associated with Alzheimer’s disease
J Luo, I Mohammed, SKTS Wärmländer, Y Hiruma, A Gräslund, ...
Biomacromolecules 15 (6), 1985-1991, 2014
282014
The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage
C Wallin, Y Hiruma, SKTS Wärmländer, I Huvent, J Jarvet, ...
Journal of the American Chemical Society 140 (26), 8138-8146, 2018
242018
Structural basis of reversine selectivity in inhibiting Mps1 more potently than aurora B kinase
Y Hiruma, A Koch, S Dharadhar, RP Joosten, A Perrakis
Proteins: Structure, Function, and Bioinformatics 84 (12), 1761-1766, 2016
172016
Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures
Y Hiruma, A Koch, N Hazraty, F Tsakou, RH Medema, RP Joosten, ...
Journal of Biological Chemistry 292 (35), 14496-14504, 2017
132017
Hot‐Spot Residues in the Cytochrome P450cam–Putidaredoxin Binding Interface
Y Hiruma, A Gupta, A Kloosterman, C Olijve, B Ölmez, MAS Hass, ...
ChemBioChem 15 (1), 80-86, 2014
132014
Interactions between N-terminal modules in MPS1 enable spindle checkpoint silencing
ST Pachis, Y Hiruma, EC Tromer, A Perrakis, GJPL Kops
Cell reports 26 (8), 2101-2112. e6, 2019
52019
Modulation of protein–ligand interactions by photocleavage of a cyclic peptide using phosphatidylinositol 3‐kinase SH3 domain as model system
I Takahashi, S Kuroiwa, HE Lindfors, LA Ndamba, Y Hiruma, T Yajima, ...
Journal of peptide science: an official publication of the European Peptide …, 2009
52009
A crystal structure of the human protein kinase Mps1 reveals an ordered conformation of the activation loop
JC Roorda, RP Joosten, A Perrakis, Y Hiruma
Proteins: Structure, Function, and Bioinformatics 87 (4), 348-352, 2019
22019
LAHMA: structure analysis through local annotation of homology-matched amino acids
B van Beusekom, G Damaskos, ML Hekkelman, F Salgado-Polo, ...
Acta Crystallographica Section D: Structural Biology 77 (1), 2021
2021
The MPS1 kinase NTE region has helical propensity and preferred conformations towards the TPR domain
Y Hiruma, MT Matsoukas, W Touw, G Spyroulias, G Kops, M Ubbink, ...
bioRxiv, 2020
2020
The Neuronal Tau Protein Blocks In Vitro Fibrillation of the Amyloid-β (Aβ) Peptide
C Wallin, Y Hiruma, S Warmlander, I Huvent, J Jarvet, JP Abrahams, ...
Biophysical Journal 116 (3), 306a, 2019
2019
MPS1 N-terminal domains interact to regulate kinetochores levels and normal mitotic progression.
ST Pachis, Y Hiruma, M Ubbink, A Perrakis, GJ Kops
MOLECULAR BIOLOGY OF THE CELL 28, 2017
2017
Cover Picture: Hot‐Spot Residues in the Cytochrome P450cam–Putidaredoxin Binding Interface (ChemBioChem 1/2014)
Y Hiruma, A Gupta, A Kloosterman, C Olijve, B Ölmez, MAS Hass, ...
ChemBioChem 15 (1), 1-1, 2014
2014
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Articles 1–20