RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage RC de Almeida, YFM Ramos, A Mahfouz, W den Hollander, N Lakenberg, ... Annals of the rheumatic diseases 78 (2), 270-277, 2019 | 158 | 2019 |
RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as … M Tuerlings, M van Hoolwerff, E Houtman, EHED Suchiman, N Lakenberg, ... Arthritis & Rheumatology 73 (5), 789-799, 2021 | 44 | 2021 |
Neo-cartilage engineered from primary chondrocytes is epigenetically similar to autologous cartilage, in contrast to using mesenchymal stem cells N Bomer, W den Hollander, H Suchiman, E Houtman, RC Slieker, ... Osteoarthritis and cartilage 24 (8), 1423-1430, 2016 | 36 | 2016 |
Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration R Coutinho de Almeida, A Mahfouz, H Mei, E Houtman, W den Hollander, ... Rheumatology 60 (3), 1166-1175, 2021 | 28 | 2021 |
Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants E Houtman, M Tuerlings, J Riechelman, EHED Suchiman, ... Arthritis Research & Therapy 23, 1-12, 2021 | 21 | 2021 |
Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling NA van Vliet, MM Bos, CS Thesing, L Chaker, M Pietzner, E Houtman, ... BMC medicine 19, 1-13, 2021 | 14 | 2021 |
Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K … E Houtman, RC de Almeida, M Tuerlings, HED Suchiman, D Broekhuis, ... Osteoarthritis and Cartilage 29 (8), 1193-1202, 2021 | 13 | 2021 |
Human osteochondral explants: reliable biomimetic models to investigate disease mechanisms and develop personalized treatments for osteoarthritis E Houtman, M van Hoolwerff, N Lakenberg, EHD Suchiman, ... Rheumatology and Therapy 8, 499-515, 2021 | 13 | 2021 |
WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes M Tuerlings, GMC Janssen, I Boone, M van Hoolwerff, AR Ruiz, ... Osteoarthritis and Cartilage 31 (1), 39-48, 2023 | 6 | 2023 |
van der Linden-van der Zwaag E, Nelissen RGHH, Ramos YFM, Meulenbelt I E Houtman, M van Hoolwerff, N Lakenberg, EHD Suchiman Human osteochondral explants: reliable biomimetic models to investigate …, 2021 | 6 | 2021 |
Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes E Houtman, M Tuerlings, HED Suchiman, N Lakenberg, FMF Cornelis, ... Rheumatology 62 (1), 457-466, 2023 | 2 | 2023 |
Circulating micro RNAs reflecting ongoing osteoarthritis pathophysiology in cartilage as applicable biomarkers YF Ramos, RC De Almeida, A Mahfouz, W Den Hollander, N Lakenberg, ... Osteoarthritis and Cartilage 27, S69, 2019 | 2 | 2019 |
Towards the elucidation of the role of osteoprotegerin in the development of osteoarthritis AR Ruiz, E Houtman, M Van Hoolwerff, N Lakenberg, RG Nelissen, ... Osteoarthritis and Cartilage 26, S87, 2018 | 1 | 2018 |
Thyroid hormone induces ossification and terminal maturation in a preserved OA cartilage biomimetic model NM Korthagen, E Houtman, I Boone, RC de Almeida, ... Arthritis Research & Therapy 26, 2024 | | 2024 |
Modelling Senescence In Osteoarthritis: Combining Irradiation And Mechanical Loading In Human Osteochondral Explants I Boone, JJ van den Berg, MV Eirin, M Tuerlings, E Houtman, M Demaria, ... Osteoarthritis and Cartilage 31, S333-S334, 2023 | | 2023 |
RNA SEQUENCING REVEALS MARKERS AND PATHWAYS OF T3-INDUCED CARTILAGE HYPERTROPHY N Korthagen, E Houtman, I Boone, RC de Almeida, K Sivasubramaniyan, ... TISSUE ENGINEERING PART A 28, S601-S601, 2022 | | 2022 |
RNA SEQUENCING REVEALS NOVEL MARKERS AND PATHWAYS OF T3-INDUCED CARTILAGE HYPERTROPHY NM Korthagen, E Houtman, I Boone, RC de Almeida, ... Osteoarthritis and Cartilage 30, S345, 2022 | | 2022 |
FUNCTIONAL GENOMICS HIGHLIGHTS ROLE FOR OSTEOARTHRITIS SUSCEPTIBILITY GENE WWP2 IN CARTILAGE MATRIX DEPOSITION M Tuerlings, G Janssen, I Boone, M van Hoolwerff, AR Ruiz, E Houtman, ... Osteoarthritis and Cartilage 30, S180, 2022 | | 2022 |
WWP2 osteoarthritis risk allele rs1052429-A confers risk by affecting cartilage matrix deposition via hypoxia associated genes M Tuerlings, GMC Janssen, I Boone, M van Hoolwerff, A Rodriguez Ruiz, ... bioRxiv, 2022.03. 31.486523, 2022 | | 2022 |
Higher thyroid stimulating hormone leads to cardiovascular disease and an unfavorable lipid profile: EVidence from multi-cohort Mendelian randomization and metabolomic profiling NA Van Vliet, MM Bos, CS Thesing, L Chaker, M Pietzner, E Houtman, ... Atherosclerosis 331, e40, 2021 | | 2021 |