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Integrins and signal transduction pathways: the road taken
EA Clark, JS Brugge
Science 268 (5208), 233-239, 1995
Cellular functions regulated by Src family kinases
SM Thomas, JS Brugge
Annual review of cell and developmental biology 13 (1), 513-609, 1997
Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
J Debnath, SK Muthuswamy, JS Brugge
Methods 30 (3), 256-268, 2003
Modelling glandular epithelial cancers in three-dimensional cultures
J Debnath, JS Brugge
Nature Reviews Cancer 5 (9), 675-688, 2005
Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases
M Rozakis-Adcock, J McGlade, G Mbamalu, G Pelicci, R Daly, W Li, ...
Nature 360 (6405), 689-692, 1992
Identification of a transformation-specific antigen induced by an avian sarcoma virus
JS Brugge, RL Erikson
Nature 269 (5626), 346-348, 1977
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
JW Locasale, AR Grassian, T Melman, CA Lyssiotis, KR Mattaini, AJ Bass, ...
Nature genetics 43 (9), 869-874, 2011
A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
XJ Ma, Z Wang, PD Ryan, SJ Isakoff, A Barmettler, A Fuller, B Muir, ...
Cancer cell 5 (6), 607-616, 2004
Sensing the environment: a historical perspective on integrin signal transduction
CK Miranti, JS Brugge
Nature cell biology 4 (4), E83-E90, 2002
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
ZT Schafer, AR Grassian, L Song, Z Jiang, Z Gerhart-Hines, HY Irie, ...
Nature 461 (7260), 109-113, 2009
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
M Overholtzer, J Zhang, GA Smolen, B Muir, W Li, DC Sgroi, CX Deng, ...
Proceedings of the National Academy of Sciences 103 (33), 12405-12410, 2006
Engineering tumors with 3D scaffolds
C Fischbach, R Chen, T Matsumoto, T Schmelzle, JS Brugge, PJ Polverini, ...
Nature methods 4 (10), 855-860, 2007
Signal transduction in cancer
R Sever, JS Brugge
Cold Spring Harbor perspectives in medicine 5 (4), 2015
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini
J Debnath, KR Mills, NL Collins, MJ Reginato, SK Muthuswamy, ...
Cell 111 (1), 29-40, 2002
Mutant p53 drives invasion by promoting integrin recycling
PAJ Muller, PT Caswell, B Doyle, MP Iwanicki, EH Tan, S Karim, ...
Cell 139 (7), 1327-1341, 2009
Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets.
L Lipfert, B Haimovich, MD Schaller, BS Cobb, JT Parsons, JS Brugge
The Journal of cell biology 119 (4), 905-912, 1992
Ras is essential for nerve growth factor-and phorbol ester-induced tyrosine phosphorylation of MAP kinases
SM Thomas, M DeMarco, G D'Arcangelo, S Halegoua, JS Brugge
Cell 68 (6), 1031-1040, 1992
Integrin-mediated signals regulated by members of the rho family of GTPases
EA Clark, WG King, JS Brugge, M Symons, RO Hynes
The Journal of cell biology 142 (2), 573-586, 1998
A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion
M Overholtzer, AA Mailleux, G Mouneimne, G Normand, SJ Schnitt, ...
Cell 131 (5), 966-979, 2007
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
D Mukhopadhyay, L Tsiokas, XM Zhou, D Foster, JS Brugge, ...
Nature 375 (6532), 577-581, 1995
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