| Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches M Chen, JL Manley Nature reviews Molecular cell biology 10 (11), 741-754, 2009 | 1504 | 2009 |
| DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. JL Manley, A Fire, A Cano, PA Sharp, ML Gefter Proceedings of the National Academy of Sciences 77 (7), 3855-3859, 1980 | 1459 | 1980 |
| HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer CJ David, M Chen, M Assanah, P Canoll, JL Manley Nature 463 (7279), 364-368, 2010 | 1258 | 2010 |
| Alternative polyadenylation of mRNA precursors B Tian, JL Manley Nature reviews Molecular cell biology 18 (1), 18-30, 2017 | 1052 | 2017 |
| Mechanism and regulation of mRNA polyadenylation DF Colgan, JL Manley Genes & development 11 (21), 2755-2766, 1997 | 1048 | 1997 |
| Structural basis for signal transduction by the Toll/interleukin-1 receptor domains Y Xu, X Tao, B Shen, T Horng, R Medzhitov, JL Manley, L Tong Nature 408 (6808), 111-115, 2000 | 1002 | 2000 |
| Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged CJ David, JL Manley Genes & development 24 (21), 2343-2364, 2010 | 948 | 2010 |
| SR proteins and splicing control 1569 JL Manley, R Tacke, BLM Hogan, KL Friedman, JD Diller, BM Ferguson, ... Genes Dev 10, 1569-1579, 1996 | 873 | 1996 |
| Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability X Li, JL Manley Cell 122 (3), 365-378, 2005 | 872 | 2005 |
| Mechanisms and consequences of alternative polyadenylation DC Di Giammartino, K Nishida, JL Manley Molecular cell 43 (6), 853-866, 2011 | 814 | 2011 |
| Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors JD Kohtz, SF Jamison, CL Will, P Zuo, R Lührmann, MA Garcia-Blanco, ... Nature 368 (6467), 119-124, 1994 | 813 | 1994 |
| The RNA polymerase II CTD coordinates transcription and RNA processing JP Hsin, JL Manley Genes & development 26 (19), 2119-2137, 2012 | 790 | 2012 |
| RNA polymerase II and the integration of nuclear events Y Hirose, JL Manley Genes & development 14 (12), 1415-1429, 2000 | 767 | 2000 |
| The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. K Colwill, T Pawson, B Andrews, J Prasad, JL Manley, JC Bell, PI Duncan The EMBO journal 15 (2), 265-275, 1996 | 753 | 1996 |
| A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy T Kashima, JL Manley Nature genetics 34 (4), 460-463, 2003 | 683 | 2003 |
| A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro H Ge, JL Manley Cell 62 (1), 25-34, 1990 | 668 | 1990 |
| Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing RJ Sims, S Millhouse, CF Chen, BA Lewis, H Erdjument-Bromage, ... Molecular cell 28 (4), 665-676, 2007 | 650 | 2007 |
| Molecular architecture of the human pre-mRNA 3′ processing complex Y Shi, DC Di Giammartino, D Taylor, A Sarkeshik, WJ Rice, JR Yates, ... Molecular cell 33 (3), 365-376, 2009 | 618 | 2009 |
| The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila CA Rushlow, K Han, JL Manley, M Levine Cell 59 (6), 1165-1177, 1989 | 588 | 1989 |
| Transcriptional repression of eukaryotic promoters M Levine, JL Manley Cell 59 (3), 405-408, 1989 | 584 | 1989 |
