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Manuela Hospenthal
Manuela Hospenthal
Group Leader at the Institute of Molecular Biology and Biophysics (IMBB), ETH Zürich, Switzerland
Verified email at mol.biol.ethz.ch - Homepage
Title
Cited by
Cited by
Year
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis
TET Mevissen, MK Hospenthal, PP Geurink, PR Elliott, M Akutsu, ...
Cell 154 (1), 169-184, 2013
5682013
OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin
K Keusekotten, PR Elliott, L Glockner, BK Fiil, RB Damgaard, Y Kulathu, ...
Cell 153 (6), 1312-1326, 2013
4682013
A comprehensive guide to pilus biogenesis in Gram-negative bacteria
MK Hospenthal, TRD Costa, G Waksman
Nature reviews microbiology 15 (6), 365-379, 2017
2492017
Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest)
MK Hospenthal, TET Mevissen, D Komander
Nature protocols 10 (2), 349-361, 2015
2032015
Ubiquitin linkage-specific affimers reveal insights into K6-linked ubiquitin signaling
MA Michel, KN Swatek, MK Hospenthal, D Komander
Molecular cell 68 (1), 233-246. e5, 2017
1882017
Assembly, analysis and architecture of atypical ubiquitin chains
MK Hospenthal, SMV Freund, D Komander
Nature structural & molecular biology 20 (5), 555-565, 2013
1662013
Non-hydrolyzable diubiquitin probes reveal linkage-specific reactivity of deubiquitylating enzymes mediated by S2 pockets
D Flierman, R Ekkebus, PP Geurink, TET Mevissen, MK Hospenthal, ...
Cell chemical biology 23 (4), 472-482, 2016
1072016
Structure of a chaperone-usher pilus reveals the molecular basis of rod uncoiling
MK Hospenthal, A Redzej, K Dodson, M Ukleja, B Frenz, C Rodrigues, ...
Cell 164 (1), 269-278, 2016
682016
The cryoelectron microscopy structure of the type 1 chaperone-usher pilus rod
MK Hospenthal, D Zyla, TRD Costa, A Redzej, C Giese, J Lillington, ...
Structure 25 (12), 1829-1838. e4, 2017
432017
Mechanism of effector capture and delivery by the type IV secretion system from Legionella pneumophila
A Meir, K Macé, N Lukoyanova, D Chetrit, MK Hospenthal, A Redzej, ...
Nature communications 11 (1), 2864, 2020
362020
Structural insights into the architecture and membrane interactions of the conserved COMMD proteins
MD Healy, MK Hospenthal, RJ Hall, M Chandra, M Chilton, V Tillu, ...
Elife 7, e35898, 2018
282018
The remarkable biomechanical properties of the type 1 chaperone-usher pilus: a structural and molecular perspective
MK Hospenthal, G Waksman
Microbiology Spectrum 7 (1), 10.1128/microbiolspec. psib-0010-2018, 2019
252019
Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation
R Schuster, V Anton, T Simġes, S Altin, F den Brave, T Hermanns, ...
Life science alliance 3 (1), 2020
122020
The molecular basis of FimT-mediated DNA uptake during bacterial natural transformation
SAG Braus, FL Short, S Holz, MJM Stedman, AD Gossert, MK Hospenthal
Nature Communications 13 (1), 1065, 2022
102022
Proteins DotY and DotZ modulate the dynamics and localization of the type IVB coupling complex of Legionella pneumophila
K Macé, A Meir, N Lukoyanova, L Liu, D Chetrit, MK Hospenthal, CR Roy, ...
Molecular Microbiology 117 (2), 307-319, 2022
72022
Ubiquitin chain analysis
TET Mevissen, MK Hospenthal, D Komander
US Patent 9,587,265, 2017
22017
Ubiquitin chain analysis
TET MEVISSEN, MK HOSPENTHAL, D Komander
12013
Ubiquitin chain assembly
MK Hospenthal, D Komander
US Patent App. 14/346,169, 2014
2014
Enzymatic assembly, structure and hydrolysis of Lys6-linked ubiquitin chains
MK Hospenthal
University of Cambridge, 2014
2014
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Articles 1–19