| The EWAS Catalog: a database of epigenome-wide association studies T Battram, P Yousefi, G Crawford, C Prince, MS Babaei, G Sharp, ... Wellcome open research 7, 2022 | 129 | 2022 |
| Insulin directly stimulates VEGF-A production in the glomerular podocyte LJ Hale, J Hurcombe, A Lay, B Santamaría, AM Valverde, MA Saleem, ... American journal of physiology-Renal physiology 305 (2), F182-F188, 2013 | 71 | 2013 |
| TRPC6 binds to and activates calpain, independent of its channel activity, and regulates podocyte cytoskeleton, cell adhesion, and motility LK Farmer, R Rollason, DJ Whitcomb, L Ni, A Goodliff, AC Lay, ... Journal of the American Society of Nephrology 30 (10), 1910-1924, 2019 | 70 | 2019 |
| Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function JA Hurcombe, P Hartley, AC Lay, L Ni, JJ Bedford, JP Leader, S Singh, ... Nature communications 10 (1), 403, 2019 | 56 | 2019 |
| Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor AC Lay, JA Hurcombe, VMS Betin, F Barrington, R Rollason, L Ni, ... Diabetologia 60, 2299-2311, 2017 | 52 | 2017 |
| Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease RD Ramnath, MJ Butler, G Newman, S Desideri, A Russell, AC Lay, ... Kidney International 97 (5), 951-965, 2020 | 50 | 2020 |
| The evolving importance of insulin signaling in podocyte health and disease AC Lay, RJM Coward Frontiers in endocrinology 9, 422323, 2018 | 42 | 2018 |
| IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes B Santamaria, E Marquez, A Lay, RMM Carew, Á González-Rodríguez, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (12), 3224-3234, 2015 | 38 | 2015 |
| Podocyte bioenergetics in the development of diabetic nephropathy: the role of mitochondria I Audzeyenka, A Bierżyńska, AC Lay Endocrinology 163 (1), bqab234, 2022 | 32 | 2022 |
| Recent advances in our understanding of insulin signalling to the podocyte A Lay, RJ Coward Nephrology Dialysis Transplantation 29 (6), 1127-1133, 2014 | 27 | 2014 |
| A role for NPY-NPY2R signaling in albuminuric kidney disease AC Lay, AF Barrington, JA Hurcombe, RD Ramnath, M Graham, PA Lewis, ... Proceedings of the National Academy of Sciences 117 (27), 15862-15873, 2020 | 19 | 2020 |
| IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes AC Lay, LJ Hale, H Stowell-Connolly, RJP Pope, V Nair, W Ju, E Marquez, ... Diabetologia 64, 1690-1702, 2021 | 16 | 2021 |
| Reduced glomerular filtration in diabetes is attributable to loss of density and increased resistance of glomerular endothelial cell fenestrations NC Finch, SS Fawaz, CR Neal, MJ Butler, VK Lee, AJ Salmon, AC Lay, ... Journal of the American Society of Nephrology 33 (6), 1120-1136, 2022 | 13 | 2022 |
| Adeno-associated virus gene therapy prevents progression of kidney disease in genetic models of nephrotic syndrome WY Ding, V Kuzmuk, S Hunter, A Lay, B Hayes, M Beesley, R Rollason, ... Science Translational Medicine 15 (708), eabc8226, 2023 | 10 | 2023 |
| An in vitro approach to understand contribution of kidney cells to human urinary extracellular vesicles K Barreiro, AC Lay, G Leparc, VDT Tran, M Rosler, L Dayalan, F Burdet, ... Journal of Extracellular Vesicles 12 (2), 12304, 2023 | 7 | 2023 |
| Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function JA Hurcombe, AC Lay, L Ni, AF Barrington, JR Woodgett, SE Quaggin, ... FASEB bioAdvances 1 (8), 498, 2019 | 6 | 2019 |
| An information theoretic approach to insulin sensing by human kidney podocytes RJP Pope, KL Garner, M Voliotis, AC Lay, VMS Betin, ... Molecular and Cellular Endocrinology 518, 110976, 2020 | 3 | 2020 |
| Does FFAR4 agonism have therapeutic potential in cardiometabolic disease? AC Lay Endocrinology 162 (10), bqab145, 2021 | 1 | 2021 |
| Contrasting consequences of podocyte IGF1R inhibition JA Hurcombe, F Barrington, M Marchetti, VMS Betin, EE Bowen, AC Lay, ... iScience, 2024 | | 2024 |
| Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets X Xu, C Khunsriraksakul, JM Eales, S Rubin, D Scannali, S Saluja, ... Nature Communications 15 (1), 2359, 2024 | | 2024 |
