Abigail C Lay
Abigail C Lay
Verified email at bristol.ac.uk
Title
Cited by
Cited by
Year
Insulin directly stimulates VEGF-A production in the glomerular podocyte
LJ Hale, J Hurcombe, A Lay, B Santamaría, AM Valverde, MA Saleem, ...
American journal of physiology-Renal physiology 305 (2), F182-F188, 2013
632013
IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes
B Santamaria, E Marquez, A Lay, RMM Carew, Á González-Rodríguez, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (12), 3224-3234, 2015
272015
TRPC6 binds to and activates calpain, independent of its channel activity, and regulates podocyte cytoskeleton, cell adhesion, and motility
LK Farmer, R Rollason, DJ Whitcomb, L Ni, A Goodliff, AC Lay, ...
Journal of the American Society of Nephrology 30 (10), 1910-1924, 2019
262019
Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor
AC Lay, JA Hurcombe, VMS Betin, F Barrington, R Rollason, L Ni, ...
Diabetologia 60 (11), 2299-2311, 2017
262017
Recent advances in our understanding of insulin signalling to the podocyte
A Lay, RJ Coward
Nephrology Dialysis Transplantation 29 (6), 1127-1133, 2014
232014
Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function
JA Hurcombe, P Hartley, AC Lay, L Ni, JJ Bedford, JP Leader, S Singh, ...
Nature communications 10 (1), 1-17, 2019
192019
The evolving importance of insulin signaling in podocyte health and disease
AC Lay, RJM Coward
Frontiers in endocrinology 9, 693, 2018
172018
Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease
RD Ramnath, MJ Butler, G Newman, S Desideri, A Russell, AC Lay, ...
Kidney international 97 (5), 951-965, 2020
132020
A role for NPY-NPY2R signaling in albuminuric kidney disease
AC Lay, AF Barrington, JA Hurcombe, RD Ramnath, M Graham, PA Lewis, ...
Proceedings of the National Academy of Sciences 117 (27), 15862-15873, 2020
42020
Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function
JA Hurcombe, AC Lay, L Ni, AF Barrington, JR Woodgett, SE Quaggin, ...
Faseb Bioadvances 1 (8), 498-510, 2019
42019
IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes
AC Lay, LJ Hale, H Stowell-Connolly, RJP Pope, V Nair, W Ju, E Marquez, ...
Diabetologia, 1-13, 2021
12021
An information theoretic approach to insulin sensing by human kidney podocytes
RJP Pope, KL Garner, M Voliotis, AC Lay, VMS Betin, ...
Molecular and Cellular Endocrinology 518, 110976, 2020
12020
An In Vitro Method to Analyze Glucose Uptake in Podocytes
AC Lay, RJ Coward
Diabetic Nephropathy, 139-143, 2020
2020
Corrigendum to “IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes”[Biochim. Biophys. Acta 1853 (12)(2015) 3224–3234]
B Santamaria, E Marquez, A Lay, RMM Carew, Á González-Rodríguez, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 4 (1863), 786, 2016
2016
FO033PODOCYTE SPECIFIC GLYCOGEN SYNTHASE KINASE 3 IS CRITICAL FOR KIDNEY FUCTION IN DEVELOPMENT AND MATURITY
JA Hurcombe, AC Lay, GI Welsh, PW Mathieson, S Patel, J Woodgett, ...
Nephrology dialysis transplantation 30 (suppl_3), iii17-iii17, 2015
2015
Understanding and modulating insulin responses of the glomerular podocyte
AC Lay
University of Bristol, 2015
2015
Full Review Recent advances in our understanding of insulin signalling to the podocyte
A Lay, RJ Coward
2013
The Evolving Importance of Insulin Signaling in Podocyte Health and
AC Lay, RJM Coward
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Articles 1–18